Psychosocial function following temporal lobectomy: influence of seizure control and learned helplessness

Seizure ◽  
1994 ◽  
Vol 3 (3) ◽  
pp. 171-176 ◽  
Author(s):  
Cathy J. Chovaz ◽  
Richard S. McLachlan ◽  
Paul A. Derry ◽  
Anne L. Cummings
Keyword(s):  
Learned Helplessness ◽  
Seizure Control ◽  
Temporal Lobectomy ◽  
Psychosocial Function

Intracarotid amobarbital test of language and memory before temporal lobectomy for seizure control

Neurology ◽  
1973 ◽  
Vol 23 (8) ◽  
pp. 812-812 ◽  
Author(s):  
W. T. Blume ◽  
J. D. Grabow ◽  
F. L. Darley ◽  
A. E. Aronson
Keyword(s):  
Seizure Control ◽  
Temporal Lobectomy ◽  
Intracarotid Amobarbital Test

Seizure and memory outcome following temporal lobe surgery: selective compared with nonselective approaches for hippocampal sclerosis

2006 ◽  
Vol 104 (1) ◽  
pp. 70-78 ◽  
Author(s):  
Eliseu Paglioli ◽  
André Palmini ◽  
Mirna Portuguez ◽  
Eduardo Paglioli ◽  
Ney Azambuja ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Verbal Memory ◽  
Seizure Control ◽  
Hippocampal Sclerosis ◽  
Surgical Techniques ◽  
Mesial Temporal Lobe Epilepsy ◽  
Outcome Data ◽  
Temporal Lobectomy ◽  
Selective Amygdalohippocampectomy

Object The aim of this study was to compare seizure and memory outcome in patients with medically refractory mesial temporal lobe epilepsy due to hippocampal sclerosis (MTLE/HS) treated using an anterior temporal lobectomy (ATL) or a selective amygdalohippocampectomy (SA). Methods Surgical outcome data were prospectively collected for 2 to 11 years in 161 consecutive patients with MTLE/HS. Eighty patients underwent an ATL and 81 an SA. Seizure control achieved with each technique was compared using the Engel classification scheme. Postoperative memory testing was performed in 86 patients (53%). At the last follow up, 72% of the patients who had undergone an ATL (mean follow up 6.7 years) and 71% of those who had undergone an SA (mean follow up 4.5 years) were seizure free (Engle Class IA). Estimated survival in patients in Engel Classes I, IA, and I and II combined did not differ between the two surgical techniques. Preoperatively, 58% of the patients had verbal memory scores one standard deviation (SD) below the normal mean. One third of the patients with preoperative scores in the normal range worsened after surgery, although this outcome was not related to the surgical technique. In contrast, one third of those whose preoperative scores were less than −1 SD experienced improvement after surgery. Nine (18%) of the 50 patients whose left side had been surgically treated improved their verbal memory scores by more than one SD. Seven (78%) of these nine underwent an SA (p = 0.05). Conclusions Both ATL and SA can lead to similar favorable seizure control in patients with MTLE/HS. Preliminary data suggest that postoperative verbal memory scores may improve in patients who undergo selective resection of a sclerotic hippocampus in the dominant temporal lobe.

scholarly journals Seizure Control and Cognitive Outcome after Temporal Lobectomy: A Comparison of Classic Ammon's Horn Sclerosis, Atypical Mesial Temporal Sclerosis, and Tumoral Pathologies

Epilepsia ◽  
2003 ◽  
Vol 44 (3) ◽  
pp. 387-398 ◽  
Author(s):  
Michele K. York ◽  
Gayle M. Rettig ◽  
Robert G. Grossman ◽  
Winifred J. Hamilton ◽  
Dawna D. Armstrong ◽  
...  
Keyword(s):  
Seizure Control ◽  
Cognitive Outcome ◽  
Temporal Lobectomy ◽  
Mesial Temporal Sclerosis ◽  
Ammon's Horn ◽  
Ammon's Horn Sclerosis ◽  
Ammon’S Horn ◽  
Ammon’S Horn Sclerosis

Selective amygdalohippocampectomy via the transsylvian approach

2008 ◽  
Vol 25 (3) ◽  
pp. E5 ◽  
Author(s):  
Badih Adada
Keyword(s):  
Visual Field ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Seizure Control ◽  
Temporal Lobectomy ◽  
Surgical Approaches ◽  
Neuropsychological Outcome ◽  
Transsylvian Approach ◽  
Selective Amygdalohippocampectomy ◽  
Established Treatment

Surgery is an established treatment for temporal lobe epilepsy refractory to medication. Several surgical approaches have been used to treat this condition including temporal lobectomy, transcortical selective amygdalohippocampectomy, subtemporal amygdalohippocampectomy, and transsylvian amygdalohippocampectomy. In this article the author reviews the transsylvian amygdalohyppocampectomy and pertinent anatomy. He also discusses the procedure's results with regard to seizure control, neuropsychological outcome, and visual field preservation.

Predictors of outcome of anterior temporal lobectomy for intractable epilepsy

Neurology ◽  
1998 ◽  
Vol 51 (2) ◽  
pp. 465-471 ◽  
Author(s):  
K. Radhakrishnan ◽  
E. L. So ◽  
P. L. Silbert ◽  
C. R. Jack ◽  
G. D. Cascino ◽  
...  
Keyword(s):  
Seizure Control ◽  
Hippocampal Formation ◽  
Intractable Epilepsy ◽  
Temporal Lobectomy ◽  
Anterior Temporal Lobectomy ◽  
Excellent Outcome ◽  
Epileptiform Discharges ◽  
Interictal Epileptiform Discharges ◽  
Univariate Analyses

Objective: To identify presurgical and postsurgical factors that are independently predictive of the outcome of anterior temporal lobectomy (ATL) for intractable epilepsy.Background: There have been reports of prognostic studied 175 consecutive ATL patients who had at least 2 years of postsurgical follow-up. Significant factors on univariate analyses were subjected to stepwise logistic regression analysis.Results: On univariate analyses, two presurgical conditions were significantly associated with excellent seizure control at last follow-up: (1) unilateral hippocampal formation atrophy as detected on MRI and (2) all scalp interictal epileptiform discharges concordant with the location of ictal onset(p < 0.05). Three postsurgical factors that occurred during the first year were associated with excellent seizure outcome: the absence of interictal epileptiform discharges at 3 months, complete seizure control, and having only nondisabling seizures for those who did not become seizure free. Logistic regression analysis revealed the following to be independently predictive of excellent seizure control: MRI-detected unilateral hippocampal formation atrophy, concordant interictal epileptiform discharges, complete seizure control during the first postsurgical year, and having only nondisabling seizures during the first postsurgical year for those who did not become seizure free.Conclusions: Presurgical identification of unilateral hippocampal formation atrophy, or of interictal epileptiform discharges that are all concordant with the location of ictal onset, predict excellent outcome of ATL. However, the probability of excellent outcome is highest (94%) when both factors are present.

Acute postoperative seizures following anterior temporal lobectomy for intractable partial epilepsy

1998 ◽  
Vol 89 (2) ◽  
pp. 177-182 ◽  
Author(s):  
Bhaskara Rao Malla ◽  
Terence J. O'Brien ◽  
Gregory D. Cascino ◽  
Elson L. So ◽  
Kurupath Radhakrishnan ◽  
...  
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Seizure Control ◽  
Temporal Lobectomy ◽  
Mesial Temporal Sclerosis ◽  
Anterior Temporal Lobectomy ◽  
Content Type ◽  
Excellent Outcome ◽  
Prognostic Importance ◽  
Fine Print

Object. Recurrence of seizures immediately following epilepsy surgery can be emotionally devastating, and raises concerns about the chances of successfully attaining long-term seizure control. The goals of this study were to investigate the frequency of acute postoperative seizures (APOS) occurring in the 1st postoperative week following anterior temporal lobectomy (ATL) to identify potential risk factors and to determine their prognostic significance. Methods. One hundred sixty consecutive patients who underwent an ATL for intractable nonlesional temporal lobe epilepsy were retrospectively studied. Acute postoperative seizures occurred in 32 patients (20%). None of the following factors were shown to be significantly associated with the occurrence of APOS: age at surgery, duration of epilepsy, side of surgery, extent of neocortical resection, electrocorticography findings, presence of mesial temporal sclerosis, and hippocampal volume measurements (p > 0.05). Patients who suffered from APOS overall had a lower rate of favorable outcome with respect to seizure control at the last follow-up examination than patients without APOS (62.5% compared with 83.6%, p < 0.05). The type of APOS was of prognostic importance, with patients whose APOS were similar to their preoperative habitual seizures having a significantly worse outcome than those whose APOS were auras or were focal motor and/or generalized tonic—clonic seizures (excellent outcome: 14.3%, 77.8%, and 75%, respectively, p < 0.05). Only patients who had APOS similar to preoperative habitual seizures were less likely to have an excellent outcome than patients without APOS (14.3% compared with 75%, p < 0.05). Timing of the APOS and identification of a precipitating factor were of no prognostic importance. Conclusions. The findings of this study may be useful in counseling patients who suffer from APOS following ATL for temporal lobe epilepsy.

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