NSC-mediated tumor selective therapy – towards glioma clinical trials

2008 ◽  
Vol 6 (9) ◽  
pp. 30
Author(s):  
K.S. Aboody ◽  
J. Najbauer ◽  
M.K. Danks ◽  
S.U. Kim ◽  
M.Z. Metz ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Selective Therapy ◽  
Tumor Selective

Development of Prodrugs for Enzyme-Mediated, Tumor-Selective Therapy

2005 ◽  
Vol 5 (2) ◽  
pp. 107-113 ◽  
Author(s):  
K. Yoon ◽  
Philip Potter ◽  
Mary Danks
Keyword(s):  
Selective Therapy ◽  
Tumor Selective

Design of tailor-made prodrugs for tumor-selective therapy

1995 ◽  
Vol 121 (S1) ◽  
pp. A51-A51
Author(s):  
K. -H. Glüsenkamp ◽  
C. Mengede ◽  
W. Drosdziok ◽  
R. Johnen ◽  
C. Krüsemann ◽  
...  
Keyword(s):  
Selective Therapy ◽  
Tumor Selective

Cell membrane camouflaged cerium oxide nanocubes for targeting enhanced tumor-selective therapy

2021 ◽  
Author(s):  
Zongjun Liu ◽  
Peng Wan ◽  
Mingxin Yang ◽  
Fang Han ◽  
Tianran Wang ◽  
...  
Keyword(s):  
Cell Membrane ◽  
Cerium Oxide ◽  
Selective Therapy ◽  
Tumor Selective

Anticancer therapies with profound efficacy but negligible toxicity is a fundamental pursuit, which has been made humanly possible so far through either targeting or tumor-selective therapeutic (TST) approach. Herein, we...

Localization of Gallium-67 in Peritoneal Cells by Electron Microscopic Autoradiography

1973 ◽  
Vol 31 ◽  
pp. 404-405
Author(s):  
D. C. Swartzendruber ◽  
Norma L. Idoyaga-Vargas
Keyword(s):  
Clinical Trials ◽  
Soft Tissue ◽  
Tumor Tissue ◽  
Soft Tissue Tumors ◽  
Clinical Usefulness ◽  
Electron Microscopic ◽  
Normal Cells ◽  
Electron Microscopic Autoradiography ◽  
Peritoneal Cells ◽  
Gallium 67

The radionuclide gallium-67 (67Ga) localizes preferentially but not specifically in many human and experimental soft-tissue tumors. Because of this localization, 67Ga is used in clinical trials to detect humar. cancers by external scintiscanning methods. However, the fact that 67Ga does not localize specifically in tumors requires for its eventual clinical usefulness a fuller understanding of the mechanisms that control its deposition in both malignant and normal cells. We have previously reported that 67Ga localizes in lysosomal-like bodies, notably, although not exclusively, in macrophages of the spocytaneous AKR thymoma. Further studies on the uptake of 67Ga by macrophages are needed to determine whether there are factors related to malignancy that might alter the localization of 67Ga in these cells and thus provide clues to discovering the mechanism of 67Ga localization in tumor tissue.

Rome I versus Rome II; Overlap in patients enrolled in tegaserod phase III clinical trials for irritable bowel syndrome (IBS)

2001 ◽  
Vol 120 (5) ◽  
pp. A284-A284
Author(s):  
B NAULT ◽  
S SUE ◽  
J HEGGLAND ◽  
S GOHARI ◽  
G LIGOZIO ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Irritable Bowel Syndrome ◽  
Phase Iii ◽  
Phase Iii Clinical Trials ◽  
Irritable Bowel ◽  
Rome I
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