287. Phase I Clinical Trial and U.S. Regulatory Experience with Designer T Cells in Cancer

Molecular Therapy ◽

10.1016/s1525-0016(16)38645-2 ◽

2009 ◽

Vol 17 ◽

pp. S112-S113

Keyword(s):

Clinical Trial ◽

T Cells ◽

Phase I ◽

Phase I Clinical Trial

Download Full-text

Local delivery of CAR T cells targeting fibroblast activation protein is safe in patients with pleural mesothelioma: first report of FAPME, a phase I clinical trial

Annals of Oncology ◽

10.1016/j.annonc.2020.10.474 ◽

2021 ◽

Vol 32 (1) ◽

pp. 120-121

Author(s):

S. Hiltbrunner ◽

C. Britschgi ◽

P. Schuberth ◽

L. Bankel ◽

T.D.L. Nguyen-Kim ◽

...

Keyword(s):

Clinical Trial ◽

T Cells ◽

Phase I ◽

Local Delivery ◽

Fibroblast Activation Protein ◽

Phase I Clinical Trial ◽

Pleural Mesothelioma ◽

First Report ◽

Car T Cells ◽

Download Full-text

Clinical scale facs-sorting and expansion of regulatory t cells (TREGS) for phase i clinical trial

Cytotherapy ◽

10.1016/s1465324921006150 ◽

2021 ◽

Vol 23 (5) ◽

pp. S196

Author(s):

A. Ekwe ◽

R. Au ◽

B. McEnroe ◽

M. Tan ◽

A. Saldan ◽

...

Keyword(s):

Clinical Trial ◽

T Cells ◽

Regulatory T Cells ◽

Phase I ◽

Phase I Clinical Trial ◽

Clinical Scale ◽

Download Full-text

Automated Manufacturing of CD20.19 Bi-Specific Chimeric Antigen Receptor T (CAR-T) Cells at an Academic Center for a Phase I Clinical Trial in Relapsed, Refractory NHL

Biology of Blood and Marrow Transplantation ◽

10.1016/j.bbmt.2018.12.143 ◽

2019 ◽

Vol 25 (3) ◽

pp. S62 ◽

Author(s):

Fenlu Zhu ◽

Nirav N Shah ◽

Dina Schneider ◽

Huiqing Xu ◽

Katherine Chaney ◽

...

Keyword(s):

Clinical Trial ◽

T Cells ◽

Phase I ◽

Chimeric Antigen Receptor ◽

Antigen Receptor ◽

Phase I Clinical Trial ◽

Automated Manufacturing ◽

Car T Cells ◽

Academic Center ◽

Download Full-text

475. Phase I Clinical Trial of Autologous CD19-Targeted 19-28z CAR T Cells in Adult Patients With Relapsed or Refractory B-ALL

Molecular Therapy ◽

10.1016/s1525-0016(16)34084-9 ◽

2015 ◽

Vol 23 ◽

pp. S188-S189 ◽

Author(s):

Jae H. Park ◽

Isabelle Riviere ◽

Xiuyan Wang ◽

Yvette Bernal ◽

Elizabeth Halton ◽

...

Keyword(s):

Clinical Trial ◽

T Cells ◽

Phase I ◽

Adult Patients ◽

Phase I Clinical Trial ◽

Car T Cells ◽

Download Full-text

A Phase I Clinical Trial With CAR-37 T Cells for the Treatment of Patients With Relapsed or Refractory CD37+ Hematologic Malignancies

Case Medical Research ◽

10.31525/ct1-nct04136275 ◽

2019 ◽

Author(s):

Keyword(s):

Clinical Trial ◽

T Cells ◽

Phase I ◽

Hematologic Malignancies ◽

Phase I Clinical Trial

Download Full-text

An oral administration of a recombinant anti-TNF fusion protein is biologically active in the gut promoting regulatory T cells: Results of a phase I clinical trial using a novel oral anti-TNF alpha-based therapy

Journal of Immunological Methods ◽

10.1016/j.jim.2017.03.023 ◽

2017 ◽

Vol 446 ◽

pp. 21-29 ◽

Author(s):

Einat Almon ◽

Tawfik Khoury ◽

Ariel Drori ◽

Svetlana Gingis-Velitski ◽

Sari Alon ◽

...

Keyword(s):

Clinical Trial ◽

T Cells ◽

Regulatory T Cells ◽

Fusion Protein ◽

Oral Administration ◽

Phase I ◽

Phase I Clinical Trial ◽

Biologically Active ◽

Download Full-text

Increase of CD4+CD25+ regulatory T cells in the peripheral blood of patients with metastatic carcinoma: a Phase I clinical trial using cyclophosphamide and immunotherapy to eliminate CD4+CD25+ T lymphocytes

Clinical & Experimental Immunology ◽

10.1111/j.1365-2249.2007.03521.x ◽

2007 ◽

Vol 150 (3) ◽

pp. 523-530 ◽

Author(s):

S. Audia ◽

A. Nicolas ◽

D. Cathelin ◽

N. Larmonier ◽

C. Ferrand ◽

...

Keyword(s):

Clinical Trial ◽

T Cells ◽

T Lymphocytes ◽

Regulatory T Cells ◽

Phase I ◽

Peripheral Blood ◽

Metastatic Carcinoma ◽

Phase I Clinical Trial

Download Full-text

World-First Phase I Clinical Trial for CRISPR-Cas9 PD-1-Edited T-Cells in Advanced Nonsmall Cell Lung Cancer

Global Medical Genetics ◽

10.1055/s-0040-1721451 ◽

2020 ◽

Vol 07 (03) ◽

pp. 073-074

Author(s):

Qian Liu

Keyword(s):

Lung Cancer ◽

Clinical Trial ◽

T Cells ◽

Phase I ◽

Cell Lung Cancer ◽

Nonsmall Cell Lung Cancer ◽

Phase I Clinical Trial

Download Full-text

Results of a Phase I Clinical Trial of Adoptive Immunotherapy for High Grade Gliomas Using Ex- Vivo Activated, Vaccine-Draining Lymph Node (LN) T Cells

Neurosurgery ◽

10.1097/00006123-199709000-00108 ◽

1997 ◽

Vol 41 (3) ◽

pp. 733-733 ◽

Author(s):

Gene H. Barnett ◽

David W. Miller ◽

Bruce Cohen ◽

Gregory E. Plautz ◽

Suyu Shu

Keyword(s):

Clinical Trial ◽

T Cells ◽

Phase I ◽

Adoptive Immunotherapy ◽

Ex Vivo ◽

Phase I Clinical Trial ◽

Draining Lymph Node ◽

High Grade Gliomas

Download Full-text

Abstract CT044: AST-008, a TLR9 agonist spherical nucleic acid, activated NK cells, T cells, and cytokines in healthy subjects in a Phase I clinical trial

10.1158/1538-7445.am2019-ct044 ◽

2019 ◽

Author(s):

Weston L. Daniel ◽

Ulrike Lorch ◽

Simon Coates ◽

Alice S. Bexon ◽

Scott Mix

Keyword(s):

Clinical Trial ◽

T Cells ◽

Nucleic Acid ◽

Phase I ◽

Nk Cells ◽

Healthy Subjects ◽

Phase I Clinical Trial ◽

Tlr9 Agonist ◽

Spherical Nucleic Acid

Download Full-text