Abstract #803: Cushing Disease Due to Pituitary Macroadenoma: Biochemical Characteristics in a Pediatric Cohort

2015 ◽  
Vol 21 ◽  
pp. 148-149
Author(s):  
Ricardo Correa ◽  
Maria Batsis ◽  
Prashant Chittiboina ◽  
Pooja Raghavan ◽  
Elena Belyavskaya ◽  
...  
Keyword(s):  
Pituitary Macroadenoma ◽  
Cushing Disease ◽  
Biochemical Characteristics

scholarly journals Invasive giant pituitary macroadenoma causing Cushing disease; a case report

2021 ◽  
Vol 11 (1) ◽  
pp. 50
Author(s):  
K. K. K. Gamage ◽  
S. Pathmanathan ◽  
N. P. Somasundaram ◽  
M. R. Sumanatilleke
Keyword(s):  
Case Report ◽  
Pituitary Macroadenoma ◽  
Cushing Disease

Recurrent cavernous sinus thrombosis: a rare complication of Cushing disease

2021 ◽  
Vol 14 (6) ◽  
pp. e243786
Author(s):  
Chin Voon Tong ◽  
Chee Kit Tee
Keyword(s):  
Cavernous Sinus ◽  
Sinus Thrombosis ◽  
Rare Complication ◽  
Pituitary Tumour ◽  
Somatostatin Analogue ◽  
Pituitary Macroadenoma ◽  
Cavernous Sinus Thrombosis ◽  
Pituitary Mass ◽  
Cushing Disease

A 14-year-old girl who presented in 2017 with headache, unilateral right eye ptosis and secondary amenorrhoea had an initial workup consistent with non-functioning pituitary macroadenoma. She underwent debulking of pituitary tumour in October 2017. Postoperatively, she developed recurrent cavernous sinus thrombosis. In view of recurrent thrombosis, she was reinvestigated and was found to have adrenocorticotropic hormone-dependent Cushing. Follow-up MRI 1 year after initial presentation showed that there was structural recurrence of pituitary macroadenoma. She subsequently underwent a petrosal craniotomy for debulking of tumour. Postsurgery she remained biochemically Cushingnoid. MRI 5 months after second surgery showed an enlarging pituitary mass which was deemed inoperable. A multidisciplinary meeting discussion consensus for treatment included radiotherapy and somatostatin analogue, pasireotide. She completed 30 cycles of radiotherapy and MRI post radiotherapy showed reduction in the size of the macroadenoma. Currently, she is waiting for pasereotide initiation.

Clinical case: Silent corticotroph pituitary macroadenoma transforming into Cushing disease.

2014 ◽  
Author(s):  
Anna Lipatenkova ◽  
Larisa Dzeranova ◽  
Ekaterina Pigarova ◽  
Anastasia Ektova
Keyword(s):  
Clinical Case ◽  
Pituitary Macroadenoma ◽  
Cushing Disease

scholarly journals Silent or Subclinical Corticotroph Pituitary Macroadenoma Transforming Into Cushing Disease

Neurosurgery ◽  
2013 ◽  
Vol 72 (1) ◽  
pp. E144-E146 ◽  
Author(s):  
Eugen Melcescu ◽  
Anthony W. Gannon ◽  
Andrew D. Parent ◽  
Jonathan F. Fratkin ◽  
William C. Nicholas ◽  
...  
Keyword(s):  
Pituitary Macroadenoma ◽  
Cushing Disease

Microtubule Dynamics and Organelle Transport in Reticulomyxa

1990 ◽  
Vol 48 (3) ◽  
pp. 194-195
Author(s):  
Yih-Tai Chen ◽  
Ursula Euteneuer ◽  
Ken B. Johnson ◽  
Michael P. Koonce ◽  
Manfred Schliwa
Keyword(s):  
Plasma Membrane ◽  
Light Microscopy ◽  
Cytoplasmic Dynein ◽  
Living Cells ◽  
Microtubule Dynamics ◽  
Model Systems ◽  
Organelle Transport ◽  
Biochemical Characteristics ◽  
Dependent Transport

The application of video techniques to light microscopy and the development of motility assays in reactivated or reconstituted model systems rapidly advanced our understanding of the mechanism of organelle transport and microtubule dynamics in living cells. Two microtubule-based motors have been identified that are good candidates for motors that drive organelle transport: kinesin, a plus end-directed motor, and cytoplasmic dynein, which is minus end-directed. However, the evidence that they do in fact function as organelle motors is still indirect.We are studying microtubule-dependent transport and dynamics in the giant amoeba, Reticulomyxa. This cell extends filamentous strands backed by an extensive array of microtubules along which organelles move bidirectionally at up to 20 μm/sec (Fig. 1). Following removal of the plasma membrane with a mild detergent, organelle transport can be reactivated by the addition of ATP (1). The physiological, pharmacological and biochemical characteristics show the motor to be a cytoplasmic form of dynein (2).

Abstract #856 A Case Series Review of Clinical and Biochemical Characteristics of Pituitary Abcess in Mexican Patients

2018 ◽  
Vol 24 ◽  
pp. 202-203
Author(s):  
Mireya Perez-Guzman ◽  
Alfredo Nava de la Vega ◽  
Arturo Pena Velarde ◽  
Tania Raisha Torres Victoria ◽  
Froylan Martinez-Sanchez ◽  
...  
Keyword(s):  
Case Series ◽  
Biochemical Characteristics ◽  
Mexican Patients
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