519 Correlation between endothelial progenitor cells and disease progression in patients with congestive heart failure

2005 ◽  
Vol 4 (1) ◽  
pp. 123-124
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Disease Progression ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Endothelial Progenitor

scholarly journals CD34+and Endothelial Progenitor Cells in Patients With Various Degrees of Congestive Heart Failure

Circulation ◽  
2004 ◽  
Vol 110 (10) ◽  
pp. 1209-1212 ◽  
Author(s):  
Marco Valgimigli ◽  
Gian Matteo Rigolin ◽  
Alessandro Fucili ◽  
Matteo Della Porta ◽  
Olga Soukhomovskaia ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Endothelial Progenitor

Circulating endothelial progenitor cells in congestive heart failure

2007 ◽  
Vol 119 (3) ◽  
pp. 344-348 ◽  
Author(s):  
Mutsuko Nonaka-Sarukawa ◽  
Keiji Yamamoto ◽  
Hirotaka Aoki ◽  
Yoshioki Nishimura ◽  
Hidenori Tomizawa ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Endothelial Progenitor ◽  
Circulating Endothelial Progenitor Cells

scholarly journals 1108-131 Kinetics of circulating endothelial progenitor cells in congestive heart failure

2004 ◽  
Vol 43 (5) ◽  
pp. A202
Author(s):  
Mutsuko Sarukawa ◽  
Keiji Yamamoto ◽  
Noriko Ueda ◽  
Yoshioki Nishimura ◽  
Masaru Ichida ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Endothelial Progenitor ◽  
Circulating Endothelial Progenitor Cells ◽  
Kinetics Of

scholarly journals Circulating endothelial progenitor cells and clinical outcome in patients with congestive heart failure

Heart ◽  
2007 ◽  
Vol 93 (9) ◽  
pp. 1046-1050 ◽  
Author(s):  
Y. Michowitz ◽  
E. Goldstein ◽  
D. Wexler ◽  
D. Sheps ◽  
G. Keren ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Clinical Outcome ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Endothelial Progenitor ◽  
Circulating Endothelial Progenitor Cells

A cardiac rehabilitation program increases the acute respond of endothelial progenitor cells after maximum exercise in patients with chronic heart failure

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
C Kourek ◽  
E Karatzanos ◽  
D Delis ◽  
M Alshamari ◽  
V Linardatou ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Exercise Training ◽  
Cardiac Rehabilitation ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Rehabilitation Program ◽  
Vascular Endothelial ◽  
Endothelial Progenitor ◽  
Maximum Exercise

Abstract Background Chronic heart failure (CHF) remains a leading cause of morbidity and mortality and it is characterized by vascular endothelial dysfunction. During the last decades, endothelial progenitor cells (EPCs) are being used as an index of the endothelium restoration potential, therefore reflecting the vascular endothelial function. Exercise training has been shown to stimulate the mobilization of EPCs at rest in CHF patients. However, the effect of exercise training on the acute respond of EPCs after maximum exercise in CHF patients remains unknown. Purpose The purpose of the study was to assess the effect of a cardiac rehabilitation (CR) program on the acute respond of EPCs after maximum exercise in patients with CHF. Methods Forty-four consecutive patients (35 males) with stable CHF [mean±SD, Age (years): 56±10, BMI (kg/m2): 28.7±5.2, EF (%): 33±8, Peak VO2 (ml/kg/min): 18.4±4.4, Peak work rate (watts): 101±39] enrolled a 36-session CR program based on high-intensity interval exercise training. All patients underwent an initial symptom limited maximal cardiopulmonary exercise testing (CPET) on an ergometer before the CR program and a final maximal CPET after the CR program. Venous blood was drawn before and after each CPET. Five circulating endothelial populations were identified and quantified by flow cytometry; CD34+/CD45-/CD133+, CD34+/CD45-/CD133+/VEGFR2, CD34+/CD133+/VEGFR2, CD34+/CD45-/CD133- and CD34+/CD45-/CD133-/VEGFR2. EPCs values are expressed as cells/million enucleated cells in medians (25th-75th percentiles). Results The acute mobilization of EPCs after the final CPET was higher than after the initial CPET in 4 out of 5 circulating endothelial populations. Most specifically, difference of the acute mobilization of CD34+/CD45-/CD133+ cells [initial CPET: 25 (15–46) vs final CPET: 49 (26–71), p=0.002], CD34+/CD45-/CD133+/VEGFR2 cells [initial CPET: 3 (2–5) vs final CPET: 8 (5–12), p<0.001], CD34+/CD45-/CD133- cells [initial CPET: 129 (52–338) vs final CPET: 250 (129–518), p=0.03] and CD34+/CD45-/CD133-/VEGFR2 cells [initial CPET: 2 (1–4) vs final CPET: 6 (3–9), p<0.001] increased after the final CPET. The acute mobilization of CD34+/CD133+/VEGFR2 cells [initial CPET: 3 (−1–7) vs final CPET: 5 (0–15), p=0.441] did not differ between the 2 CPETS. Conclusion A 36-session cardiac rehabilitation program increases the acute respond of endothelial progenitor cells after maximum cardiopulmonary exercise training in patients with chronic heart failure, therefore indicating the beneficial effect of exercise training on the vascular endothelial function. Funding Acknowledgement Type of funding source: Public grant(s) – EU funding. Main funding source(s): Co-financed by Greece and the European Union (European Social Fund- ESF) through the Operational Programme “Human Resources Development, Education and Lifelong Learning” in the context of the project

Are endothelial progenitor cells a prognostic factor in patients with heart failure?

2012 ◽  
Vol 10 (2) ◽  
pp. 167-175 ◽  
Author(s):  
Ana Carolina Alba ◽  
Diego Hernan Delgado ◽  
Vivek Rao ◽  
Stephen Walter ◽  
Gordon Guyatt ◽  
...  
Keyword(s):  
Heart Failure ◽  
Prognostic Factor ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Endothelial Progenitor ◽  
Patients With Heart Failure

scholarly journals Endothelial progenitor cells mobilization after maximal exercise in patients with chronic heart failure

2020 ◽  
Author(s):  
Christos Kourek ◽  
Eleftherios Karatzanos ◽  
Katherina Psarra ◽  
Argyrios Ntalianis ◽  
Georgios Mitsiou ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Progenitor Cells ◽  
Endothelial Progenitor Cells ◽  
Maximal Exercise ◽  
Endothelial Progenitor
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