793 Do ventricular arrhythmias influence mortality in post myocardial infarction patients with heart failure?

2007 ◽  
Vol 6 (1) ◽  
pp. 181-182
Author(s):  
R SANKARANARAYANAN ◽  
M JAMES ◽  
S BURTCHAELL ◽  
R HOLLOWAY
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Ventricular Arrhythmias ◽  
Post Myocardial Infarction ◽  
Patients With Heart Failure

P4453Predictors of sustained ventricular arrhythmias during late phase in patients with reduced left ventricular ejection fraction after myocardial infarction

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
K Saito ◽  
Y Kondo ◽  
H Kitahara ◽  
T Nakayama ◽  
Y Fujimoto ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Left Ventricular Ejection Fraction ◽  
Ejection Fraction ◽  
Ventricular Arrhythmias ◽  
Late Phase ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Ventricular Ejection Fraction ◽  
Patients With Heart Failure

Abstract Background Sustained ventricular arrhythmias (VAs) and death are feared events post myocardial infarction (post-MI). Patients with heart failure post-MI have higher risk of VAs, compared to those without heart failure. Although the risk of sudden cardiac arrest and death post-MI isn't small, previous clinical trials have failed to demonstrate the benefit of early use of implantable cardioverter defibrillators. Moreover, little is known about the relationship between the acute phase and the late phase VAs in patients with heart failure post-MI. Purpose The aim of this study was to determine the predictors of the late phase VAs in patients with heart failure post MI. Methods We retrospectively analyzed our database of MI patients from January 2012 to September 2016. Results A total of consecutive 460 post-MI patients were included in this study (age, 67±12 year-old; male, 336 (73%); STEMI, 281 (61%)). All the patients underwent primary percutaneous coronary intervention. Of those, 90 patients (20%) had depressed left ventricular ejection fraction (LVEF) ≤35%. After a mean follow up period of 30±16 months, 45 patients (50%) had VAs after MI. Among them, 35 patients (78%) had VAs within 48 hours after MI onset, 8 patients (18%) within 7 days 48 hours later, and 21 patients (47%) more than 7 days. Cox-regression analysis showed that VAs within 7 days 48 hours later after MI onset was significantly related to sustained VAs more than 7 days after MI onset (Hazard Ratio, 4.97; 95% Confidence Interval, 1.31–18.9; p=0.019). Conclusions VAs in the sub-acute phase after MI predicted sustained VAs in the late phase in this population. Prompt initiation of aggressive antiarrhythmic therapies, including catheter ablation, after MI should be considered to reduce the mortality.

Levosimendan improves contractilityin vivoandin vitroin a rodent model of post-myocardial infarction heart failure

2014 ◽  
Vol 210 (4) ◽  
pp. 865-874 ◽  
Author(s):  
S. M. Kolseth ◽  
N. P. L. Rolim ◽  
Ø. Salvesen ◽  
D. O. Nordhaug ◽  
A. Wahba ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Heart Failure ◽  
Rodent Model ◽  
Post Myocardial Infarction ◽  
Infarction Heart
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