WO8-OR-6 CAROTID INTIMA-MEDIA THICKNESS, CAROTID DISTENSIBILITY AND MITRAL, AORTIC VALVE CALCIFICATION: A USEFUL DIAGNOSTIC PARAMETER OF SYSTEMIC ATHEROSCLEROTIC DISEASE

2007 ◽  
Vol 8 (1) ◽  
pp. 9
Author(s):  
L. Sgorbini ◽  
G. Di Donato
Keyword(s):  
Aortic Valve ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Atherosclerotic Disease ◽  
Diagnostic Parameter ◽  
Aortic Valve Calcification ◽  
Valve Calcification ◽  
Media Thickness ◽  
Carotid Distensibility

scholarly journals Premature Valvular Heart Disease in Homozygous Familial Hypercholesterolemia

Cholesterol ◽  
2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Akl C. Fahed ◽  
Kamel Shibbani ◽  
Rabih R. Andary ◽  
Mariam T. Arabi ◽  
Robert H. Habib ◽  
...  
Keyword(s):  
Heart Disease ◽  
Aortic Valve ◽  
Familial Hypercholesterolemia ◽  
Valvular Heart Disease ◽  
Young Patients ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Lipid Lowering ◽  
Aortic Valve Calcification ◽  
Valve Calcification

Valvular heart disease frequently occurs as a consequence of premature atherosclerosis in individuals with familial hypercholesterolemia (FH). Studies have primarily focused on aortic valve calcification in heterozygous FH, but there is paucity of data on the incidence of valvular disease in homozygous FH. We performed echocardiographic studies in 33 relatively young patients (mean age: 26 years) with homozygous FH (mean LDL of 447 mg/dL, 73% on LDL apheresis) to look for subclinical valvulopathy. Twenty-one patients had evidence of valvulopathy of the aortic or mitral valves, while seven subjects showed notable mitral regurgitation. Older patients were more likely to have aortic valve calcification (>21 versus ≤21 years: 59% versus 12.5%; p = 0.01) despite lower LDL levels at the time of the study (385 versus 513 mg/dL; p = 0.016). Patients with valvulopathy were older and had comparable LDL levels and a lower carotid intima-media thickness. Our data suggests that, in homozygous FH patients, valvulopathy (1) is present across a wide age spectrum and LDL levels and (2) is less likely to be influenced by lipid-lowering treatment. Echocardiographic studies that focused on aortic root thickening and stenosis and regurgitation are thus likely an effective modality for serial follow-up of subclinical valvular heart disease.

scholarly journals 908 Evaluation of carotid intima-media thickness in patients with aortic valve calcifications

2003 ◽  
Vol 4 ◽  
pp. S118
Author(s):  
A KABLAKZIEMBICKA ◽  
T PRZEWLOCKI ◽  
A MURA ◽  
P PODOLEC ◽  
M PASOWICZ ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness

scholarly journals Strain Pattern on Electrocardiogram Is Associated with Increased Carotid Intima-Media Thickness in Patients with Aortic Valve Stenosis

2016 ◽  
Vol 35 ◽  
pp. 197-202
Author(s):  
Meliza Goi Roscani ◽  
Gustavo N. Augusto ◽  
Tainá F.C. Valadão ◽  
Jonas A. Araújo ◽  
Juliana C. Duarte ◽  
...  
Keyword(s):  
Aortic Valve ◽  
Aortic Valve Stenosis ◽  
Intima Media Thickness ◽  
Carotid Intima Media Thickness ◽  
Media Thickness ◽  
Strain Pattern
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