scholarly journals P304 Cyclosporine or infliximab as rescue therapy in severe refractory ulcerative colitis: Early and long-term data from a retrospective observational study

2012 ◽  
Vol 6 ◽  
pp. S131
Author(s):  
F. Mocciaro ◽  
S. Renna ◽  
A. Orlando ◽  
G. Rizzuto ◽  
E. Sinagra ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Observational Study ◽  
Rescue Therapy ◽  
Retrospective Observational Study ◽  
Term Data

scholarly journals Cyclosporine or infliximab as rescue therapy in severe refractory ulcerative colitis: Early and long-term data from a retrospective observational study

2012 ◽  
Vol 6 (6) ◽  
pp. 681-686 ◽  
Author(s):  
Filippo Mocciaro ◽  
Sara Renna ◽  
Ambrogio Orlando ◽  
Giulia Rizzuto ◽  
Emanuele Sinagra ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Observational Study ◽  
Rescue Therapy ◽  
Retrospective Observational Study ◽  
Term Data

scholarly journals Tacrolimus or infliximab for severe ulcerative colitis: short-term and long-term data from a retrospective observational study

2015 ◽  
Vol 2 (1) ◽  
pp. e000021 ◽  
Author(s):  
Naoki Minami ◽  
Takuya Yoshino ◽  
Minoru Matsuura ◽  
Yorimitsu Koshikawa ◽  
Satoshi Yamada ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Observational Study ◽  
Retrospective Observational Study ◽  
Short Term ◽  
Severe Ulcerative Colitis ◽  
Term Data

Infliximab or Cyclosporine as Rescue Therapy in Hospitalized Patients with Steroid-Refractory Ulcerative Colitis: A Retrospective Observational Study

2012 ◽  
Vol 18 (2) ◽  
pp. 212-218 ◽  
Author(s):  
Mats Sjöberg ◽  
Andrea Walch ◽  
Mina Meshkat ◽  
Anders Gustavsson ◽  
Gunnar Järnerot ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Observational Study ◽  
Rescue Therapy ◽  
Hospitalized Patients ◽  
Retrospective Observational Study ◽  
Steroid Refractory

Adalimumab effectiveness in Behçet’s disease: short and long-term data from a multicenter retrospective observational study

2016 ◽  
Vol 36 (2) ◽  
pp. 451-455 ◽  
Author(s):  
Antonio Vitale ◽  
Giacomo Emmi ◽  
Giuseppe Lopalco ◽  
Stefano Gentileschi ◽  
Elena Silvestri ◽  
...  
Keyword(s):  
Observational Study ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Retrospective Observational Study ◽  
Behcet's Disease ◽  
Short And Long Term ◽  
Term Data

scholarly journals Long-term postoperative opioid prescription after cholecystectomy or gastric by-pass surgery: a retrospective observational study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Viktoria Larsson ◽  
Cecilia Nordenson ◽  
Pontus Karling
Keyword(s):  
Observational Study ◽  
Postoperative Period ◽  
Medical Records ◽  
Early Postoperative Period ◽  
Retrospective Observational Study ◽  
Opioid Use ◽  
Opioid Prescription ◽  
Post Surgery ◽  
Gastric By Pass

Abstract Objectives Opioids are commonly prescribed post-surgery. We investigated the proportion of patients who were prescribed any opioids 6–12 months after two common surgeries – laparoscopic cholecystectomy and gastric by-pass (GBP) surgery. A secondary aim was to examine risk factors prior to surgery associated with the prescription of any opioids after surgery. Methods We performed a retrospective observational study on data from medical records from patients who underwent cholecystectomy (n=297) or GBP (n=93) in 2018 in the Region of Västerbotten, Sweden. Data on prescriptions for opioids and other drugs were collected from the patients` medical records. Results There were 109 patients (28%) who were prescribed opioids after discharge from surgery but only 20 patients (5%) who still received opioid prescriptions 6–12 months after surgery. All 20 of these patients had also been prescribed opioids within three months before surgery, most commonly for back and joint pain. Only 1 out of 56 patients who were prescribed opioids preoperatively due to gallbladder pain still received prescriptions for opioids 6–12 months after surgery. Although opioid use in the early postoperative period was more common among patients who underwent cholecystectomy, the patients who underwent GBP were more prone to be “long-term” users of opioids. In the patients who were prescribed opioids within three months prior to surgery, 8 out of 13 patients who underwent GBP and 12 of the 96 patients who underwent cholecystectomy were still prescribed opioids 6–12 months after surgery (OR 11.2; 95% CI 3.1–39.9, p=0,0002). Affective disorders were common among “long-term” users of opioids and prior benzodiazepine and amitriptyline use were significantly associated with “long-term” opioid use. Conclusions The proportion of patients that used opioids 6–12 months after cholecystectomy or GBP was low. Patients with preoperative opioid-use experienced a significantly higher risk of “long-term” opioid use when undergoing GBP compared to cholecystectomy. The indication for being prescribed opioids in the “long-term” were mostly unrelated to surgery. No patient who was naïve to opioids prior surgery was prescribed opioids 6–12 months after surgery. Although opioids are commonly prescribed in the preoperative and in the early postoperative period to patients with gallbladder disease, there is a low risk that these prescriptions will lead to long-term opioid use. The reasons for being prescribed opioids in the long-term are often due to causes not related to surgery.

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