scholarly journals Lung microbiota predict chronic rejection in healthy lung transplant recipients: a prospective cohort study

2021 ◽  
Author(s):  
Michael P Combs ◽  
David S Wheeler ◽  
Jenna E Luth ◽  
Nicole R Falkowski ◽  
Natalie M Walker ◽  
...  
Keyword(s):  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Chronic Rejection ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
Lung Transplant Recipients ◽  
Healthy Lung

scholarly journals The Prediction and Prognosis of Fungal Infection in Lung Transplant Recipients—A Retrospective Cohort Study in South Korea

2021 ◽  
Vol 7 (8) ◽  
pp. 639
Author(s):  
Yae-Jee Baek ◽  
Yun-Suk Cho ◽  
Moo-Hyun Kim ◽  
Jong-Hoon Hyun ◽  
Yu-Jin Sohn ◽  
...  
Keyword(s):  
Cohort Study ◽  
South Korea ◽  
Fungal Infection ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Lung Transplant ◽  
Fungal Infections ◽  
Transplant Recipients ◽  
Tertiary Center ◽  
Lung Transplant Recipients

(1) Background: Lung transplant recipients (LTRs) are at substantial risk of invasive fungal disease (IFD), although no consensus has been reached on the use of antifungal agents (AFAs) after lung transplantation (LTx). This study aimed to assess the risk factors and prognosis of fungal infection after LTx in a single tertiary center in South Korea. (2) Methods: The study population included all patients who underwent LTx between January 2012 and July 2019 at a tertiary hospital. It was a retrospective cohort study. Culture, bronchoscopy, and laboratory findings were reviewed during episodes of infection. (3) Results: Fungus-positive respiratory samples were predominant in the first 90 days and the overall cumulative incidence of Candida spp. was approximately three times higher than that of Aspergillus spp. In the setting of itraconazole administration for 6 months post-LTx, C. glabrata accounted for 36.5% of all Candida-positive respiratory samples. Underlying connective tissue disease-associated interstitial lung disease, use of AFAs before LTx, a longer length of hospital stay after LTx, and old age were associated with developing a fungal infection after LTx. IFD and fungal infection treatment failure significantly increased overall mortality. Host factors, antifungal drug resistance, and misdiagnosis of non-Aspergillus molds could attribute to the breakthrough fungal infections. (4) Conclusions: Careful bronchoscopy, prompt fungus culture, and appropriate use of antifungal therapies are recommended during the first year after LTx.

Management of Urological Malignancy in Heart and Lung Transplant Recipients: An Irish National Cohort Study

2021 ◽  
Vol 19 (10) ◽  
pp. 1069-1075
Author(s):  
Robert A. Keenan ◽  
Usman Haroon ◽  
Paul Ryan ◽  
Bronagh Harrington ◽  
Andrew Jones ◽  
...  
Keyword(s):  
Cohort Study ◽  
Lung Transplant ◽  
Transplant Recipients ◽  
National Cohort ◽  
Lung Transplant Recipients

The Psychosocial Assessment of Candidates for Transplantation: A Cohort Study of its Association With Survival Among Lung Transplant Recipients

2016 ◽  
Vol 57 (5) ◽  
pp. 489-497 ◽  
Author(s):  
Mario J. Hitschfeld ◽  
Terry D. Schneekloth ◽  
Cassie C. Kennedy ◽  
Teresa A. Rummans ◽  
Shehzad K. Niazi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Lung Transplant ◽  
Psychosocial Assessment ◽  
Transplant Recipients ◽  
Lung Transplant Recipients
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