scholarly journals Antibacterial efficacy of the seed extracts of Melia azedarach against some hospital isolated human pathogenic bacterial strains

2011 ◽  
Vol 1 (6) ◽  
pp. 452-455 ◽  
Author(s):  
Abdul Viqar Khan ◽  
Qamar Uddin Ahmed ◽  
M Ramzan Mir ◽  
Indu Shukla ◽  
Athar Ali Khan
Processes ◽  
2020 ◽  
Vol 8 (1) ◽  
pp. 113 ◽  
Author(s):  
Mervat EL-Hefny ◽  
Mohamed Z. M. Salem ◽  
Said I. Behiry ◽  
Hayssam M. Ali

In the present study, Melia azedarach wood blocks treated with different acetone extract concentrations from Withania somnifera fruits are assessed for their antibacterial and anti-fungal activities. Wood blocks of M. azedarach treated with W. somnifera fruit extract at concentrations of 0, 1, 2, and 3% are evaluated for in vitro antimicrobial activity against five genbank accessioned bacterial strains—Agrobacterium tumefaciens, Dickeya solani, Erwinia amylovora, Pseudomonas cichorii, and Serratia pylumthica—and two fungi, namely, Fusarium culmorum and Rhizoctonia solani. Through HPLC analysis we find that the most abundant quantified phenolic and flavonoid compounds of acetone extract (mg/100 g) are salicylic acid (9.49), vanillic acid (4.78), rutin (4702.58), and myricetin (1386.62). Wood treated with the extract at 2% and 3% show no growth of A. tumefaciens, E. amylovora, and P. cichorii. Use of the extract at 3% causes inhibition of fungal mycelia of F. culmorum and R. solani by 84.07% and 67.03%, respectively. In conclusion, potent antifungal and antibacterial activity against plant pathogens is found when an acetone extract of W. somnifera fruits is applied to wood samples.


2016 ◽  
Vol 1 (1-2) ◽  
pp. 05-09 ◽  
Author(s):  
Samuel L. Oputah ◽  
Kolawole O. Ajanaku ◽  
Raphael C. Mordi ◽  
Joseph A. O. Olugbuyiro ◽  
Shade J. Olorunshola ◽  
...  

Phytochemical and antibacterial properties of ethanolic extract of the seeds of African Star Apple (Chrysophyllum albidum) were investigated. The phytochemical result revealed the presence of saponins, carbohydrates, flavonoids, quinones, cardiac glycosides, fatty acids and terpenoids. The antibacterial activity was studied using agar well diffusion method at different concentrations against six pathogenic bacterial strains, three Gram-positive (Staphylococcus aureus, Micrococcus varians and Bacillus cereus) and three Gram-negative (Escherichia coli, Pseudomonas aeruginosa and Proteus vulgaris). Significant inhibitory activities were exhibited by the ethanolic seed extracts for all test organisms except Bacillus cereus. Zone of inhibition of the crude ethanolic extract was correlated with that of a standard antibiotic Gentamicin, for antibacterial activity. The results indicated a notable inhibition of the bacterial growth.


Plants ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1445
Author(s):  
Sangeeta Chandrashekar ◽  
Raman Vijayakumar ◽  
Ramachandran Chelliah ◽  
Deog-Hwan Oh

The aim of the study was to investigate the antibacterial and anticoagulant activity of Moringa (Moringa oleifera) seed extracts and coagulant protein for their potential application in water treatment. Pathogenic microorganisms were obtained from Ramachandra Hospital, Chennai, India. Bacterial cell aggregation and growth kinetics studies were employed for six bacterial strains with different concentrations of seed extracts and coagulant protein. Moringa seed extract and coagulant protein showed cell aggregation against six bacterial strains, whereas seed extract alone showed growth inhibition of all six bacterial strains for up to 6 h, compared to that of control. Escherichia coli and Salmonella para typhi B did not develop resistance against coagulant protein. The results imply that Moringa oleifera is likely an efficient low-molecular bioactive peptide (with <7.5 kDa plant-based coagulant and antimicrobial peptides, confirmed by applying amino acid sequences), using liquid chromatography–mass spectrometry and HPLC, with the corresponding sequences from Napin-1A peptide posing different degrees of antibacterial activity against different pathogenic organisms.


2020 ◽  
pp. 1-2
Author(s):  
Rim M Harfouch ◽  
◽  
Rawan Fead ◽  
Lubana Hammoud ◽  
◽  
...  

Propolis is a natural material that can be found in bee honey. It has many medical uses due to its antibacterial activity. In this study we aimed to estimate the antibacterial efficacy of three propolis extracts using three different solvents (Ethanol, Methanol and Ethyl Acetate). We experienced the three extracts on four different strains of bacteria (Klebsiella pneumonia, Ecoli, Pseudomonas aruginosa & Staphylococcus aureus). The results indicated that all the studied propolis extractions do not have any efficacy on Klebsiella neither on Ecoli. The methanolic extract has the greatest effect on Staphylococcus aureus as well as on Pseudomonas aruginosa in contrast of ethanolic and ethyle acetatic extracts which has no efficacy on any of the studied bacterial strains.


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