Indicators of Potentially Drug-Resistant Bacteria in Severe Nursing Home-Acquired Pneumonia

2006 ◽  
Vol 2006 ◽  
pp. 185
Author(s):  
J.R. Maurer
2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S159-S160
Author(s):  
Oya Özlem Eren-Kutsoylu ◽  
Vildan Avkan-Oguz ◽  
Madina Abdullayeva ◽  
Nil Tekin ◽  
Nur Yapar

2004 ◽  
Vol 39 (4) ◽  
pp. 474-480 ◽  
Author(s):  
A. A. E. Solh ◽  
C. Pietrantoni ◽  
A. Bhat ◽  
M. Bhora ◽  
E. Berbary

2021 ◽  
Vol 6 (3) ◽  
pp. 123
Author(s):  
Aikaterini Moschou ◽  
Petros Ioannou ◽  
Eleni Moraitaki ◽  
Dimitra Stafylaki ◽  
Sofia Maraki ◽  
...  

(1) Background: In an area with a high prevalence of multi-drug resistant Gram-negative bacteria (MDR-GNB), we investigated the colonization of nursing home residents by such organisms. (2) Methods: A point prevalence study was performed in six nursing homes of the Heraklion area on the island of Crete. A rectal swab was taken and cultured from each participant, while additional risk factors such as recent hospitalization or antimicrobial usage were recorded and evaluated. (3) Results: A total of 137 nursing home residents were included in the study. Their mean age was 82.1 years and 19.7% were males. In total, cultures yielded 255 GNB; E. coli, K. pneumoniae and P. aeruginosa were the most common. Among the microorganisms cultured, 17.6% had the extended-spectrum beta-lactamase phenotype, while 18% were MDR. A statistically significant association was found between recent antimicrobial use and colonization by MDR-GNB; (4) Conclusions: Colonization by MDR-GNB was found to be highly prevalent in nursing home residents. Recent antimicrobial use was associated with MDR-GNB carriage.


CHEST Journal ◽  
2004 ◽  
Vol 126 (4) ◽  
pp. 845S ◽  
Author(s):  
Ali A. El Solh ◽  
Celestino Pietrantoni ◽  
Abid Bhat ◽  
Milapchand Bhora ◽  
Eileen Berbary

Author(s):  
E.A. Martis ◽  
G M Doshi ◽  
G V Aggarwal ◽  
P P Shanbhag

With the emergence of newer diseases, resistant forms of infectious diseases and multi-drug resistant bacteria, it has become essential to develop novel and more effective antibiotics. Current antibiotics are obtained from terrestrial life or made synthetically from intermediates. The ocean represents virtually untapped resource from which novel antibiotic compounds can be discovered. It is the marine world that will provide the pharmaceutical industry with the next generation of antibiotics. Marine antibiotics are antibiotics obtained from marine organisms. Scientists have reported the discovery of various antibiotics from marine bacteria (aplasmomycin, himalomycins, and pelagiomycins), sponges (Ara C, variabillin, strobilin, ircinin-1, aeroplysin, 3,5-dibromo-4-hydroxyphenylacetamide), coelenterates (asperidol and eunicin), mollusks (laurinterol and pachydictyol), tunicates (geranylhydroquinone and cystadytins), algae (cycloeudesmol, aeroplysinin-1(+), prepacifenol and tetrabromoheptanone), worms (tholepin and 3,5-dibromo-4-hydroxybezaldehyde), and actinomycetes (marinomycins C and D). This indicates that the marine environment, representing approximately half of the global diversity, is an enormous resource for new antibiotics and this source needs to be explored for the discovery of new generation antibiotics. The present article provides an overview of various antibiotics obtained from marine sources.


Author(s):  
Daniel Berman

How can we prevent the rise of resistance to antibiotics? In this video, Daniel Berman,  Nesta Challenges, discusses the global threat of AMR and how prizes like the Longitude Prize can foster the development of rapid diagnostic tests for bacterial infections, helping to contribute towards reducing the global threat of drug resistant bacteria. Daniel outlines how accelerating the development of rapid point-of-care tests will ensure that bacterial infections are treated with the most appropriate antibiotic, at the right time and in the right healthcare setting.


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