Adverse effects of drug treatment

Medical Harm ◽  
1998 ◽  
pp. 175-193 ◽  
Keyword(s):  
Adverse Effects ◽  
Drug Treatment

scholarly journals Treatment of epilepsy – towards precision

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1932 ◽  
Author(s):  
John Paul Leach
Keyword(s):  
Genetic Testing ◽  
Adverse Effects ◽  
Drug Treatment ◽  
Antiepileptic Drug ◽  
Precision Medicine ◽  
Treatment Of Epilepsy ◽  
Antiepileptic Drug Treatment

Epilepsy was among the first disease areas to begin to apply principles of precision medicine to its treatment. This review looks at the role of investigation in ensuring the safety and effectiveness of antiepileptic drug treatment. Using sound principles, we can see that the use of genetic testing will advance treatment of epilepsy in reducing harm and adverse effects and enhancing efficacy.

scholarly journals Pharmacodynamic modeling of adverse effects of anti-cancer drug treatment

2016 ◽  
Vol 72 (6) ◽  
pp. 645-653 ◽  
Author(s):  
A. H. M. de Vries Schultink ◽  
A. A. Suleiman ◽  
J. H. M. Schellens ◽  
J. H. Beijnen ◽  
A. D. R. Huitema
Keyword(s):  
Adverse Effects ◽  
Drug Treatment ◽  
Cancer Drug ◽  
Pharmacodynamic Modeling ◽  
Anti Cancer ◽  
Cancer Drug Treatment

Diets and Obesity Drug Treatment

1996 ◽  
Vol 9 (5) ◽  
pp. 330-341
Author(s):  
James T. O'Donnell
Keyword(s):  
Adverse Effects ◽  
Drug Treatment ◽  
Weight Control ◽  
Single Agent ◽  
New Approach ◽  
Appetite Suppression ◽  
Two Agents ◽  
Pharmacologically Active

Weight control and dieting is a subject of great interest to the American public. The use of pharmacologically active agents to help take weight off and keep it off has ranged from following the golden rules of moderation, not eating to excess, and following a regular plan of exercise. Many people are unable or unwilling to maintain these well-known practices and have sought out chemical means of assisting them is losing weight and keeping it off. The sympathomimetics have a powerfully effective appetite suppression, but also have a long list of serious and habituating adverse effects. Many diets have employed specific schedules and types of food to eat or avoid, but there is no diet employing drugs that is completely safe and effective. One new diet, Fen-Phen represents a new approach. Instead of using a single agent, a combination of two agents is used which affects the brain's neurotransmitters. The results have been impressive so far, but the adverse effects of these two agents and their use and possible interaction with other drugs remains a risk.

Antilibidinal Drugs and Mental Retardation: A Review

1989 ◽  
Vol 29 (2) ◽  
pp. 136-146 ◽  
Author(s):  
David J. Clarke
Keyword(s):  
Mental Retardation ◽  
Adverse Effects ◽  
Drug Treatment ◽  
Sexual Behaviour ◽  
Medroxyprogesterone Acetate ◽  
Cyproterone Acetate ◽  
Attitudinal Change ◽  
Inclusion Criteria ◽  
Sexual Drive ◽  
Sexual Counselling

A minority of people with mental retardation have sexual behaviour which is socially unacceptable or which brings them into conflict with the law. Such behaviour may be the result of ignorance about sexual matters, often best managed by counselling or by a behavioural approach. There are a small number of men with mental retardation and aberrant sexual behaviour who benefit from the prescription of an antilibidinal drug. Treatment with an antilibidinal drug alone reduces the intensity of sexual drive but does not alter its direction; concurrent sexual counselling or psychotherapy is often indicated. The various antilibidinal medications available are reviewed, with particular attention to reports which have described the treatment of people with mental retardation. Of the antilibidinals currently used, medroxyprogesterone acetate and cyproterone acetate are those for which there is most evidence of efficacy. Cyproterone acetate is preferable because it has a specific antiandrogenic action and fewer adverse effects. There is a need for controlled studies of antilibidinal drugs, with clearly defined inclusion criteria and adequate measures of both behavioural and attitudinal change.

scholarly journals Identifying Adverse Effects of HIV Drug Treatment and Associated Sentiments Using Twitter

2015 ◽  
Vol 1 (2) ◽  
pp. e7 ◽  
Author(s):  
Cosme Adrover ◽  
Todd Bodnar ◽  
Zhuojie Huang ◽  
Amalio Telenti ◽  
Marcel Salathé
Keyword(s):  
Adverse Effects ◽  
Drug Treatment
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