scholarly journals LO45: Incidence of delayed intracranial hemorrhage following a mild traumatic brain injury in patients taking anticoagulants or anti-platelets therapies: systematic review and meta-analysis

CJEM ◽  
2018 ◽  
Vol 20 (S1) ◽  
pp. S22-S22
Author(s):  
M. Emond ◽  
A. Laguë ◽  
T. O’Brien ◽  
B. Mitra ◽  
P. Tardif ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ct Scan ◽  
Intracranial Hemorrhage ◽  
Meta Analysis ◽  
Grey Literature ◽  
Experimental Studies ◽  
Discharge Plan ◽  
Mesh Terms ◽  
Traumatic Intracranial Hemorrhage ◽  
Clinically Significant

Introduction: Head injury is a common presentation to all emergency departments. Previous research has shown that such injuries may be complicated by delayed intracranial hemorrhage (D-ICH) after the initial scan is negative. Exposure to anticoagulant or anti-platelet medications (ACAP) may be a risk factor for D-ICH. We have conducted a systematic review and meta-analysis to determine the incidence of delayed traumatic intracranial hemorrhage in patients taking anticoagulants, anti-platelets or both. Methods: The literature search was conducted in March 2017 with an update in April 2017. Keyword and MeSH terms were used to search OVID Medline, Embase and the Cochrane database as well as grey literature sources. All cohort and experimental studies were eligible for selection. Inclusion criteria included pre-injury exposure to oral anticoagulant and / or anti-platelet medication and a negative initial CT scan of the brain (CT1). The primary outcome was delayed intracranial hemorrhage present on repeat CT scan (CT2) within 48 hours of the presentation. Only patients who were rescanned or observed minimally were included. Clinically significant D-ICH were those that required neurosurgery, caused death or necessitated a change in management strategy, such as admission. Results: Fifteen primary studies were ultimately identified, comprising a total of 3801 patients. Of this number, 2111 had a control CT scan. 39 cases of D-ICH were identified, with the incidence of D-ICH calculated to be 1.31% (95% CI [0.56, 2.27]). No more than 12 of these patients had a clinically significant D-ICH representing 0.09% (95% CI [0.00, 0.31]). 10 of them were on warfarin and two on aspirin. There were three deaths recorded and three patients needed neurosurgery. Conclusion: The relatively low incidence suggests that repeat CT should not be mandatory for patients without ICH on first CT. This is further supported by the negligibly low rate of clinically significant D-ICH. Evidence-based assessments should be utilised to indicate the appropriate discharge plan, with further research required to guide the balance between clinical observation and repeat CT.

scholarly journals Women’s decision in family planning use and its determinants in Ethiopia. A systematic review and meta-analysis protocol

2021 ◽  
Author(s):  
Etsay Woldu Anbesu ◽  
Setognal Birara Aychiluhm ◽  
Mussie Alemayehu
Keyword(s):  
Systematic Review ◽  
Decision Making ◽  
Family Planning ◽  
Contraceptive Use ◽  
Meta Analysis ◽  
Statistical Significance ◽  
Grey Literature ◽  
Reproductive Health Services ◽  
Mesh Terms ◽  
Meta Analyses

Abstract Background Low uptake of contraceptive use have much consequence on maternal and child health. Despite this effect, less emphasis was given to women’s decision-making on family planning use in Ethiopia. Though there are studies conducted in different parts of the country on women’s decision-making in family planning use, there are inconsistent findings. Thus, this systematic review and meta-analysis aimed to determine the pooled prevalence of women’s decision-making in family planning use and its determinants in Ethiopia. Methods Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline will be followed to develop the review protocol. All observational studies will be retrieved using Medical Subject Heading (Mesh) terms or keywords from online databases PubMed, CINAHL, Google Scholar, and unpublished grey literature from May 10-11August/2021. The quality of the studies will be critically assessed using Joanna Briggs Institute checklist. Heterogeneity among studies will be examined using I-squared statistics. Funnel plots and Egger’s test will be used to examine publication bias. The Meta-analysis will be performed using STATA version 14 software. Statistical significance will be determined at 95% CI. Discussion Improving women’s autonomy on decision-making on reproductive health services including contraceptive use has a substantial advantage. There are studies on women’s decision-making in family planning use and this systematic review and meta-analysis will help policymakers to develop appropriate interventions.

Systematic Review and Meta-Analysis: Is Pre-Injury Antiplatelet Therapy Associated with Traumatic Intracranial Hemorrhage?

2017 ◽  
Vol 34 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Crispijn L. van den Brand ◽  
Tanya Tolido ◽  
Anna H. Rambach ◽  
Myriam G.M. Hunink ◽  
Peter Patka ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antiplatelet Therapy ◽  
Intracranial Hemorrhage ◽  
Meta Analysis ◽  
Traumatic Intracranial Hemorrhage

scholarly journals Women’s decision in family planning use and its determinants in Ethiopia: A systematic review and meta-analysis protocol

2021 ◽  
Author(s):  
Etsay Woldu Anbesu ◽  
Setognal Birara Aychiluhm ◽  
Mussie Alemayehu
Keyword(s):  
Systematic Review ◽  
Decision Making ◽  
Family Planning ◽  
Contraceptive Use ◽  
Meta Analysis ◽  
Statistical Significance ◽  
Grey Literature ◽  
Reproductive Health Services ◽  
Mesh Terms ◽  
Meta Analyses

Abstract Background Low uptake of contraceptive use have much consequence on maternal and child health. Despite this effect, less emphasis was given to women’s decision-making on family planning use in Ethiopia. Though there are studies conducted in different parts of the country on women’s decision-making in family planning use, there are inconsistent findings. Thus, this systematic review and meta-analysis aimed to determine the pooled prevalence of women’s decision-making in family planning use and its determinants in Ethiopia. Methods Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline will be followed to develop the review protocol. All observational studies will be retrieved using Medical Subject Heading (Mesh) terms or keywords from online databases PubMed, CINAHL, Google Scholar, and unpublished grey literature from May 10-11August/2021. The quality of the studies will be critically assessed using Joanna Briggs Institute checklist. Heterogeneity among studies will be examined using I-squared statistics. Funnel plots and Egger’s test will be used to examine publication bias. The Meta-analysis will be performed using STATA version 14 software. Statistical significance will be determined at 95% CI. Discussion Improving women’s autonomy on decision-making on reproductive health services including contraceptive use has a substantial advantage. There are studies on women’s decision-making in family planning use and this systematic review and meta-analysis will help policymakers to develop appropriate interventions.

scholarly journals The effect of women’s body mass index on pelvic organ prolapse: a systematic review and meta analysis

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Chernet Baye Zenebe ◽  
Wagaye Fentahun Chanie ◽  
Aster Berhe Aregawi ◽  
Tamiru Minwuye Andargie ◽  
Muhabaw Shumye Mihret
Keyword(s):  
Systematic Review ◽  
Body Mass Index ◽  
Body Weight ◽  
Pelvic Organ Prolapse ◽  
Body Mass ◽  
Meta Analysis ◽  
Grey Literature ◽  
Experimental Studies ◽  
Pelvic Organ ◽  
Cross Sectional

Abstract Background Pelvic organ prolapse remains the public health challenge globally. Existing evidences report the effect of woman’s weight on the pelvic organ prolapse inconsistently and this urges the need of pooled body weight effect on the pelvic organ prolapse. Although there was a previous work on this regard, it included papers reported before June 18/2015. Thus, updated and comprehensive evidence in this aspect is essential to devise strategies for interventions. Objective This review aimed at synthesizing evidence regarding the pooled effect of body weight on the pelvic organ prolapsed. Methods For this review, we searched all available articles through databases including PubMed, Web of Sciences, CINAHL, JBI library, Cochran library, PsycInfo and EMBASE as well as grey literature including Mednar, worldwide science, PschEXTRA and Google scholar. We included cohort, case–control, cross-sectional and experimental studies which had been reported between March 30, 2005 to March 30, 2020. In the effect analysis, we utilized random model. The heterogeneity of the studies was determined by I2 statistic and the publication bias was checked by Egger’s regression test. Searching was limited to studies reported in the English language. Results A total of 14 articles with 53,797 study participants were included in this systematic review (SR) and meta analysis (MA). The pooled result of this Meta analyses depict that body mass index (BMI) doesn’t have statistical significant association with pelvic organ prolapse. Conclusion This review point out that women’s body mass index has no significant effect on the development of pelvic organ prolapse. However, the readers should interpret the result with cautions due to the presence of considerable limitations in this work. Trial registration The protocol of this systematic review (SR) and meta analysis (MA) has been registered in PROSPERO databases with the Registration number of CRD42020186951

scholarly journals Mindfulness-Based Interventions to Reduce Burnout in Primary Healthcare Professionals: A Systematic Review and Meta-Analysis

Healthcare ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 1342
Author(s):  
Mafalda Salvado ◽  
Diogo Luís Marques ◽  
Ivan Miguel Pires ◽  
Nádia Mendes Silva
Keyword(s):  
Systematic Review ◽  
Primary Healthcare ◽  
Healthcare Professionals ◽  
Meta Analysis ◽  
Experimental Studies ◽  
Risk Of Bias ◽  
Personal Accomplishment ◽  
High Quality Research ◽  
Mesh Terms ◽  
Mean Differences

Mindfulness-based interventions (MBIs) are reported by experimental studies as practical approaches to reduce burnout in primary healthcare professionals (PHCP). However, to date, no research has synthesized the evidence to determine the overall effects of MBIs for reducing burnout in PHCP. We conducted a systematic review and meta-analysis to analyze the effects of MBIs to reduce burnout in PHCP. We searched articles in the PubMed/MEDLINE, Web of Science, Cochrane, and Scopus databases from inception to September 2021 using MeSH terms: “mindfulness”, “burnout”, and “primary healthcare”. Two reviewers extracted the data and assessed the risk of bias. We used a random-effects meta-analysis to calculate the standardized mean differences (SMD) and mean differences (MD) with 95% confidence intervals (CI) of emotional exhaustion (EE), depersonalization (DP), and personal accomplishment (PA) domains of burnout. Of 61 records, ten were included (n = 417). Overall, the studies were rated as having a high risk of bias and limited quality evidence. MBIs significantly reduced EE (SMD = −0.54, 95%CI: −0.72 to −0.36; MD = −5.89, 95%CI: −7.72 to −4.05), DP (SMD = −0.34, 95%CI: −0.52 to −0.17; MD = −1.96, 95%CI: −2.96 to −0.95), and significantly increased PA (SMD = 0.34, 95%CI: 0.17 to 0.52; MD = 2.05, 95%CI: 1.04 to 3.06). Although further high-quality research is needed, our findings support the implementation of MBIs for reducing burnout in PHCP.

scholarly journals Women’s decision in family planning use and its determinants in Ethiopia. A systematic review and meta-analysis protocol

2021 ◽  
Author(s):  
Etsay Woldu Anbesu ◽  
Setognal Birara Aychiluhm ◽  
Mussie Alemayehu
Keyword(s):  
Systematic Review ◽  
Decision Making ◽  
Family Planning ◽  
Contraceptive Use ◽  
Meta Analysis ◽  
Statistical Significance ◽  
Grey Literature ◽  
Reproductive Health Services ◽  
Mesh Terms ◽  
Pooled Prevalence

Abstract Background: Low uptake of contraceptive use have much consequence. Despite this effect, less emphasis was given to women’s decision-making on family planning use in Ethiopia. Though there are studies conducted in different parts of the country on women’s decision-making in family planning use, there are inconsistent findings. Thus, this systematic review and meta-analysis aimed to determine the pooled prevalence of women’s decision-making in family planning use and its determinants in Ethiopia.Methods: Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline will be followed to develop the review protocol. All observational studies will be retrieved using Medical Subject Heading (Mesh) terms or keywords from online databases PubMed, CINAHL, Google Scholar, and grey literature. The quality of the studies will be critically assessed using Joanna Briggs Institute checklist. Heterogeneity among studies will be examined using I-squared statistics. Funnel plots and Egger’s test will be used to examine Publication bias. The Meta-analysis will be performed using STATA version 14 software. Statistical significance will be determined at 95% CI.Discussion: Improving women’s autonomy on decision-making on reproductive health services including contraceptive use has a substantial advantage. There are studies on women's decision-making in family planning use, however, there are inconsistent findings. Therefore, this review aims to determine the pooled prevalence of women’s decision-making in family planning use and its determinants in Ethiopia. The finding from this systematic review and meta-analysis will help to inform policymakers to develop appropriate interventions to improve women's decision-making in family planning use.

Sign in / Sign up

Export Citation Format

Share Document