scholarly journals 27416 DNA Methylation Age Acceleration and Depressive Symptoms in African American Women with Cardiometabolic Conditions

2021 ◽  
pp. 1-2
Author(s):  
Nicole Perez ◽  
Allison Vorderstrasse ◽  
Gary Yu ◽  
Jacquelyn Taylor
Keyword(s):  
Dna Methylation ◽  
African American ◽  
Depressive Symptoms ◽  
African American Women ◽  
American Women ◽  
Dna Methylation Age

scholarly journals Association of Obesity with DNA Methylation Age Acceleration in African American Mothers from the InterGEN Study

2019 ◽  
Vol 20 (17) ◽  
pp. 4273 ◽  
Author(s):  
Chengchen Li ◽  
Zeyuan Wang ◽  
Theresa Hardy ◽  
Yunfeng Huang ◽  
Qin Hui ◽  
...  
Keyword(s):  
Dna Methylation ◽  
African American ◽  
African American Women ◽  
Biological Aging ◽  
African American Mothers ◽  
American Women ◽  
Related Disease ◽  
Disease Outcomes ◽  
Dna Methylation Age ◽  
High Bmi

African American women are affected by earlier onset of age-associated health deteriorations and obesity disproportionally, but little is known about the mechanism linking body mass index (BMI) and biological aging among this population. DNA methylation age acceleration (DNAm AA), measuring the difference between DNA methylation age and chronological age, is a novel biomarker of the biological aging process, and predicts aging-related disease outcomes. The present study estimated cross-tissue DNA methylation age acceleration using saliva samples from 232 African American mothers. Cross-sectional regression analyses were performed to assess the association of BMI with DNAm AA. The average chronological age and DNA methylation age were 31.67 years, and 28.79 years, respectively. After adjusting for smoking, hypertension diagnosis history, and socioeconomic factors (education, marital status, household income), a 1 kg/m2 increase in BMI is associated with 0.14 years increment of DNAm AA (95% CI: (0.08, 0.21)). The conclusion: in African American women, high BMI is independently associated with saliva-based DNA methylation age acceleration, after adjusting for smoking, hypertension, and socioeconomic status. This finding supports that high BMI accelerates biological aging, and plays a key role in age-related disease outcomes among African American women.

African American Women and Depression: Promoting the Need for Culturally Competent Treatment

2018 ◽  
Author(s):  
Bernice Kennedy ◽  
Chalice Jenkins ◽  
Keyword(s):  
Mental Health ◽  
African American ◽  
Depressive Symptoms ◽  
African American Women ◽  
Mental Health Problems ◽  
American Woman ◽  
Stressful Events ◽  
Mental Illnesses ◽  
Diagnostic Process ◽  
American Women

Abstract Depression is gradually increasing in African American women. These women are experiencing role changes and additional life stressors. Depressed African American women may perceive themselves as being devalued by society with fewer support systems to buffer stressful events. Depressive symptoms may develop into clinical depression and a further decrease in the quality of life for the African American woman. The assumption that all women share similar experiences does not allow for differences to emerge regarding the diagnostic process, measuring tools, and successful treatment strategies for various cultures. The authors developed a Multifaceted Model of Depression in African American Women for improving treatment of African American women with depression and future research needs. Cultural background plays a vital role in how the symptoms of mental illnesses are developed, reported, interpreted, and how women are treated. African Americans who subscribed to the Strong Black Women Archetype (SBWA) are naturally strong, resilient, self-contained, and self-sacrificing. This self-reliance prevents them from reaching out for social support. This, in turn, can contribute to depressive symptoms with negative health outcomes. The African American women are more apt to have less access to routine medical care where early diagnosis and interventions can be done, so their mental health problems (e.g., depression, stress, etc.) are often more developed, complicated, and their social supports more depleted when they do access treatment. When African American women do have access to mental health care, they receive poor quality care compared to Whites.

scholarly journals HIV Prevention Programming for Older African American Women: The Impact of a Faith-Based and Behavioral Science Partnership on Depressive Symptoms

2020 ◽  
Vol 30 (2) ◽  
pp. 287-294
Author(s):  
Megan T. Ebor ◽  
Aurora P. Jackson
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
Hiv Prevention ◽  
African American Women ◽  
Psychological Wellbeing ◽  
American Women ◽  
Faith Based ◽  
Older African American Women ◽  
The One ◽  
The Impact

Objective: The current study sought to test the effect of an HIV prevention interven­tion on depressive symptoms in a sample of older African American women.Design, Setting and Participants: A pretest-posttest randomized control group design was conducted in a mega-church in Los Angeles with a sample of 62 older African American women, aged ≥50 years, 29 of whom were randomly assigned to the experimental condition and 33 to the comparison/control condition.Measures: A measure of psychological wellbeing (CES-D) was utilized to test the effect of the four-session group interven­tion vs the one-session informational group intervention on change in depressive symp­toms from pretest to posttest. Demographic characteristics included: measures of age in years; relationship and employment statuses (coded 1 for yes, 0 for no); and educational attainment.Results: Participation in the study was as­sociated with a significant improvement in the women’s psychological wellbeing from baseline to time 2; ie, decreased depres­sive symptoms. This change was greater for women in the four-session experimental group than for those in the one-session comparison group, due in part to a margin­ally significant interaction between time and experimental conditions.Conclusions: This study demonstrates the utility of faith-based/behavioral-scientist partnerships in HIV programming. Findings contribute to the evidence on interventions that might reduce depressive symptoms and HIV risk among older African American women. Ethn Dis. 2020;30(2):287-294; doi:10.18865/ed.30.2.287

scholarly journals Discriminatory Experiences and Depressive Symptoms among African American Women: Do Skin Tone and Mastery Matter?

Sex Roles ◽  
2009 ◽  
Vol 62 (1-2) ◽  
pp. 48-59 ◽  
Author(s):  
Verna M. Keith ◽  
Karen D. Lincoln ◽  
Robert Joseph Taylor ◽  
James S. Jackson
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
African American Women ◽  
Skin Tone ◽  
American Women

scholarly journals Psychosocial and Sociocultural Correlates of Depressive Symptoms Among Diverse African American Women

2012 ◽  
Vol 104 (11-12) ◽  
pp. 493-504 ◽  
Author(s):  
Kisha B. Holden ◽  
Stephanie P. Hall ◽  
Maryam Robinson ◽  
Sharra Triplett ◽  
Dolapo Babalola ◽  
...  
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
African American Women ◽  
American Women

scholarly journals How Depressive Symptoms among African American Women Relate to Measures of Social Disorder in Her Childhood and Pregnancy Neighborhood

2020 ◽  
Vol 97 (1) ◽  
pp. 26-36
Author(s):  
Alexandra L. Nowak ◽  
Carmen Giurgescu ◽  
Thomas N. Templin ◽  
Rhonda K. Dailey ◽  
Dawn P. Misra
Keyword(s):  
African American ◽  
Depressive Symptoms ◽  
African American Women ◽  
Social Disorder ◽  
American Women
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