scholarly journals The efficacy of the probiotic feed additive Calsporin® (Bacillus subtilis C-3102) in broilers: combined analysis of four different studies

2012 ◽  
Vol 1 ◽  
Author(s):  
T. Marubashi ◽  
M. I. Gracia ◽  
E. Esteve-Garcia ◽  
M. Piskoríková

SummaryThe efficacy of the probiotic feed additive, Calsporin® (CAL; Bacillus subtilis C-3102), included in broiler diets at 50 mg/kg was evaluated using statistical meta-analysis of data from four different studies conducted using broilers from day-old to market weight at 42 days of age. The body weight, average daily gain, feed intake, feed to gain ratio, mortality and European Production Efficiency Factor (EPEF) data from each experiment were tested for homogeneity between trials before being pooled and analysed in combination to determine whether benefits were consistent independent of trial site and conditions. CAL supplementation significantly improved weight gain (P = 0.0037) between 1 and 21 days of age (3.3%) and feed conversion ratio (P = 0.0492) between 22 and 42 days of age (3.0%). Over the entire experimental period (day 1 to day 42 of age), broilers fed the CAL diets had significantly better (P = 0.0142) feed conversion (2.6%) and higher (P = 0.0062) EPEF (4.6%) compared to the controls. Birds fed diets supplemented with CAL were 1.6% heavier than controls at 42 days of age, a near-significant trend (P = 0.0558). The results demonstrated that CAL in broiler diets, added at an inclusion rate of 50 mg/kg, can be beneficial in terms of broiler performance.

Author(s):  
T. Marubashi ◽  
M. I. Gracia ◽  
B. Vilà ◽  
V. Bontempo ◽  
S. K. Kritas ◽  
...  

SummaryThe efficacy of the probiotic feed product, Calsporin® (Bacillus subtilis C-3102) in weaned piglets was evaluated by statistical analysis of the combined results from four different experiments. The body weight, average daily gain, feed intake, feed conversion ratio and mortality data from these four experiments were tested for homogeneity before being pooled and analysed as a whole, with experiment being included as a blocking factor. Piglets fed diets supplemented with Calsporin® were significantly heavier (3.4%) at 43 days (P < 0.05), their feed intakes decreased by 2.1% and feed efficiency (FCR) improved by 3.2% between 15 and 43 days, although these latter differences were not significant. Over the entire study period (day 1 to 43), significant improvements in daily gain (4.8%) and feed efficiency (6.2%) were observed with Calsporin® supplementation (P < 0.05). The results demonstrated that Calsporin® at 30 mg/kg inclusion in commercial-type diets can improve zootechnical performance in weaned piglets.


PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0247820
Author(s):  
Breanna M. Roque ◽  
Marielena Venegas ◽  
Robert D. Kinley ◽  
Rocky de Nys ◽  
Toni L. Duarte ◽  
...  

The red macroalgae (seaweed) Asparagopsis spp. has shown to reduce ruminant enteric methane (CH4) production up to 99% in vitro. The objective of this study was to determine the effect of Asparagopsis taxiformis on CH4 production (g/day per animal), yield (g CH4/kg dry matter intake (DMI)), and intensity (g CH4/kg ADG); average daily gain (ADG; kg gain/day), feed conversion efficiency (FCE; kg ADG/kg DMI), and carcass and meat quality in growing beef steers. Twenty-one Angus-Hereford beef steers were randomly allocated to one of three treatment groups: 0% (Control), 0.25% (Low), and 0.5% (High) A. taxiformis inclusion based on organic matter intake. Steers were fed 3 diets: high, medium, and low forage total mixed ration (TMR) representing life-stage diets of growing beef steers. The Low and High treatments over 147 days reduced enteric CH4 yield 45 and 68%, respectively. However, there was an interaction between TMR type and the magnitude of CH4 yield reduction. Supplementing low forage TMR reduced CH4 yield 69.8% (P <0.01) for Low and 80% (P <0.01) for High treatments. Hydrogen (H2) yield (g H2/DMI) increased (P <0.01) 336 and 590% compared to Control for the Low and High treatments, respectively. Carbon dioxide (CO2) yield (g CO2/DMI) increased 13.7% between Control and High treatments (P = 0.03). No differences were found in ADG, carcass quality, strip loin proximate analysis and shear force, or consumer taste preferences. DMI tended to decrease 8% (P = 0.08) in the Low treatment and DMI decreased 14% (P <0.01) in the High treatment. Conversely, FCE tended to increase 7% in Low (P = 0.06) and increased 14% in High (P <0.01) treatment compared to Control. The persistent reduction of CH4 by A. taxiformis supplementation suggests that this is a viable feed additive to significantly decrease the carbon footprint of ruminant livestock and potentially increase production efficiency.


2018 ◽  
Vol 28 (4) ◽  
pp. 323-330 ◽  
Author(s):  
HR Tanzim ◽  
GB Das ◽  
M Ahmad ◽  
M Barua ◽  
K Islam

This study was conducted to determine the effect of phytogenic feed additive and prebiotic on vegetable protein base diet in broiler performance.  A total of 90 chicks (Cobb-500) were weighted and randomly assigned to the three treatment groups (To, T1 and T2) and supplemented with either phytogenic feed additives or prebiotic and reared for 28 days. Data on live body weight, body weight gain, feed intake and feed conversion (FC) were taken at weekly interval. Results revealed that significant (P<0.05) increase in live body weight of broilers was evident in both phytogenic feed additive and prebiotic supplemented groups comparing to the control group at 4th weeks of age. No significant (P>0.05) differences were found in live weight gain among the treatment groups on weekly intervals along the whole experimental period. However, significant differences (P<0.05) were evident on cumulative weight gain at 3rd and 4th weeks of age. In case of feed intake at the age of 3rd and 4th weeks, significant (P<0.05) differences were obtained with decreased feed intake in both phytogenic feed additive and prebiotic supplemented groups comparing to the control group. In case of feed conversion (FC), there were significant (P<0.05) differences among the groups on 1st week and 4th week of age. Best FC was accounted for prebiotic supplemented group along the whole experimental period. The survivability rates were 96.67%, 100% and 100% in control group, phytogenic feed additive and prebiotic supplemented group respectively. Results finally showed that vegetable protein when supplemented with phytogenic prebiotic feed additives and prebiotic c an additive beneficial effect on performance of when compared to non-supplemented control diet. So, ration using vegetable protein mixed with phytogenic feed additives or prebiotic can be recommended for broiler.Progressive Agriculture 28 (4): 323-330, 2017


2019 ◽  
Vol 8 (4) ◽  
pp. 9631-9636 ◽  

This study was aimed at studying the biological characteristics of the calves of the Hereford and Simmental breeds, and crosses of these breeds in Siberia. The article discusses the peculiarities of metabolism and utilization of nutrients, growth rate, meat productivity and quality, feed conversion in groups of calves up to 15.5 months of age due to the breed identity in the keeping conditions in light facilities and cold climate. Similarity has been noted in the parameters of gas-and-energy metabolism in Hereford and crossbred calves, including their seasonal dynamics. During the experimental period, a seasonal downward trend was noted in the heart rate of Hereford calves by 11.4 %, and respiration rate — by 33.8 %. In the Simmental peers, these figures decreased by 12 and 37.2 %, respectively, in hybrids — by 6.1 and 29 %. The seasonal decrease in the body temperature in Hereford and crossbred animals by 2.4 – 2.5 %, in Simmentals — by 1.3 %, and increased heat production by Hereford animals and their crosses — by 20.9 and 20.1 % (P<0.01), compared to the Simmental peers, were noted. In terms of the content of hemoglobin, Hereford calves (116.5 ± 3.6 g/l) and Hereford × Simmental hybrids (114.0 ± 5.1 g/l) tended to be superior to Simmental calves (103.5 ± 5.4 g/l). No significant difference in the erythrocytes count in the blood of calves was found between the groups. In all ages, Simmental calves were inferior to their Hereford and crossbred peers in terms of the content of total protein and albumin in the blood serum. By the content of globulins in the blood serum, no differences were found between the groups. The coefficients of nutrients digestibility due to balanced feeding was relatively high in all groups. Hereford × Simmental hybrids were superior to their Simmental counterparts by the organic matter digestibility by 3.0 % (P<0.01). The most significant difference in the live weight was observed between Simmental and crossbred calves (P<0.01). The average daily gain of the hybrids over the entire study period was greater by 25.6 and 15.2 % than that of purebred Simmental and Hereford calves. Accordingly, Hereford × Simmental calves had an advantage over Herefords in terms of the slaughtering weight by 5.4 %, and over Simmentals — by 22.1 %. The energy value of the meat of purebred Herefords and crossbred calves was higher by 8.4 % than in purebred Simmentals. The conclusion has been made about the prospects of using Herefords and their crosses with Simmentals for the sustainable development of beef cattle breeding in the conditions of Siberia.


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 201-201
Author(s):  
Yan Martel-Kennes ◽  
Caroline Decaux ◽  
Carl Julien

Abstract Development of natural alternatives to drugs is necessary for the poultry industry not only for organic production, but also for limiting drug resistance and for complying with upcoming regulations. Two pen trials were conducted to evaluate the effect of Calica+, an activated vegetal oil from cashew nut shell liquid (CNSL), on broiler performance and on coccidiosis in different conditions. The first trial was conducted in Eimeria vaccination conditions with commercial Coccivac-B52. The second one was realized in Eimeria challenge conditions, induced by an oral administration of 200,000 sporulated oocysts of mixed Eimeria species harvested from field isolates. In Eimeria vaccination conditions trial, Calica+ improved average daily gain (ADG) (+4.5%, P &lt; 0.05) during the overall growing period and decreased levels of oocysts per gram of feces (OPG) (−44.1%, P &lt; 0.05), at Eimeria excretion peak (days 17–20), compared to untreated broilers. However, no significant effect of Calica+ on Eimeria intestinal lesions was observed. Overall ADG in Calica+-treated birds was not significantly different compared to nicarbazin-monensin anticoccidial medication (P = 0.8362) but showed higher feed conversion ratio (FCR; +6.0%, P &lt; 0.05). In Eimeria challenge conditions trial, Calica+ feeding treatment improved ADG after infection, during the period from d20 to d36 of age (+4.4%, P &lt; 0.05) compared to untreated birds. Compared with nicarbazin-monensin medication, Calica+-treated birds showed higher FCR (+3.5%, P &lt; 0.05), but comparable ADG (P = 0.3145). Interestingly, birds fed the treatment with Calica+ showed a trend of increased plasmatic levels of IL-1ß compared to untreated broilers (+25.6%, P = 0.0676), suggesting an immune activation as a potential mechanism of action for Calica+. In summary, Calica+ showed beneficial growth performance and anticoccidial effects in these two different trial conditions. This feed additive could be involved in a strategy to reduce the use of anticoccidial medication in broiler production.


2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 472-472
Author(s):  
Benjamin Bass ◽  
Stacie Crowder ◽  
Murali Raghavendra Rao

Abstract Ambitine Feed Additive (AMB), a proprietary blend of phytogenics and acidifiers (PMI, Arden Hills, MN), is formulated to help mitigate late finishing stress in pigs. Several studies using AMB in the late finishing period resulted in improved pig performance. A meta-analytic method used 13 studies (3 studies with ractopamine and 10 studies without) to determine the overall impact of AMB on average daily gain, average daily feed intake, and feed conversion. The combined data were considered a randomized complete block design. Analysis of variance was completed using the GLIMMIX procedure of SAS (9.4; Cary, NC) and least squares means were compared using Fisher’s least significant difference (P &lt; 0.05). In the analysis of 10 studies with no added ractopamine (73 pens/treatment of 5 to 10 pigs/pen and 48 pens/treatment of 17 to 20 pigs/pen), pigs provided AMB had higher average daily gain (0.90 vs 0.86 kg/d; P &lt; 0.05), increased average daily feed intake (2.99 vs 2.94 kg/d; P &lt; 0.05), and improved feed efficiency (0.30 vs 0.29 kg gain/kg feed intake; P &lt; 0.05) compared to pigs fed control diets. Additionally, when pigs were provided AMB in addition to ractopamine (3 studies; 33 pens/treatment of 18 to 22 pigs/pen), average daily gain was increased 4.7% (1.206 vs 1.152 kg/d; P &lt; 0.05) and feed efficiency was improved 5.3% (0.40 vs 0.38 kg gain/kg feed intake; P &lt; 0.05) compared to pigs provided only ractopamine, with no difference in feed intake. Pigs provided AMB in addition to ractopamine had increased hot carcass weight and dressing percentage (P &lt; 0.05) compared to those provided ractopamine alone. In conclusion, providing AMB to pigs in late finishing improved ADG and feed efficiency and the improvement was maintained when ractopamine was included in the diets.


Author(s):  
J.G. Vicente-Martínez ◽  
J.M. Pinos-Rodriguez ◽  
J.C. García-López ◽  
V.R. León-Cabada ◽  
J.M. Martínez-Hernández ◽  
...  

Background: Due to the resistance that various pathogens have developed to the unplanned use of antibiotic growth promoters (AGPs) and the risk to consumers health that this implies, AGPs could be replaced by natural products such as plants, essential oils or extracts. The current study was aimed to investigate the effects of a feed additive based on papaveraceae roots and nanoclays (Sangromix 10x®) on broiler performance. Methods: One hundred and twenty Cobb broilers one d old, were randomly assigned to a diet without additive or with additive at 20 g/t during 49 d. Broilers had free access to concentrate and fresh water and were weighed daily. Feed intake and body weight was measured daily and where used to estimate average daily gain and feed conversion ratio. Result: Broilers that received Sangromix 10x®, had higher final body weight, total gain, average daily gain and better feed conversion value as compared with broilers with no additive. The additive did not affect feed intake. The inclusion of Sangromix 10x® increased final body weight and improved feed conversion value and it can be concluded that is an efficient alternative for broiler production. Nevertheless, further research is required to determine their effect on meat and carcass quality, internal organs and blood biochemistry.


2020 ◽  
Vol 21 (3) ◽  
pp. 74-79
Author(s):  
Ahmed Elbaz ◽  
Said El-sheikh

Objective: To investigate the effect of antibiotics and/or probiotics on broiler performance, some serum metabolites, cecum microflora composition, and ileum histomorphology under the Egyptian conditions. Design: Randomized controlled experimental study. Animals: Two hundred forty 1-day-old Ross (308) chicks were reared till 35 days of age. Procedures: The birds were randomly allocated into four main groups: a control diet without additives (CON); probiotic (Lactobacillus acidophilus) supplemented diet (PRO); antibiotic (Avilamycin) supplemented diet (ANT) and a mix group (AP) that received antibiotic in the diet form 1 to 4 days of age and treated during the rest of the experimental period with probiotics. Results: Chickens fed on probiotic or antibiotic diets had linear improvement in live body weight (LBW) and feed conversion ratio (FCR) compared with the control group, while the best LBW and FCR were in the AP group. An improvement in the nutrient digestibility was observed in the probiotic added groups (PRO and AP). Serum cholesterol and low-density lipoprotein cholesterol contents decreased when antimicrobial (probiotic or antibiotic) supplementations were used, while there was an increase in high-density lipoprotein cholesterol contents, serum total protein, and albumin levels. Among all groups, cecum Clostridium perfringens and Escherichia coli counts decreased; however, there was an increase in Lactobacillus count compared to the control group. In probiotic supplemented groups (PRO and AP), a significant (P<0.05) improvement in ilea architecture. Conclusion and clinical relevance: Using probiotic after initial treatment with an antibiotic in broiler diets had a positive effect on broiler growth performance, gut health (improved cecum microbial populations and ileum histomorphology), and nutrient digestibility.


Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1581
Author(s):  
Artur Rybarczyk ◽  
Elżbieta Bogusławska-Wąs ◽  
Alicja Dłubała

The objective of the study was to determine the effects of probiotic bacteria Bacillus licheniformis and Bacillus subtilis on microbiological properties of feed mixtures and on the digestive tract content as applicable to production traits and carcass characteristics of fatteners. The experiment was performed on 83,838 fatteners from four successive (insertions) productions in two groups. From the seventy eighth day of age till marketing to the slaughter plant, the pigs were supplied with BioPlus YC probiotic (Chr. Hansen) in the amount of 400 g/t. The preparation contained a complex of probiotic bacteria Bacillus licheniformis DSM 5749, and Bacillus subtilis DSM 5750 spores in a 1:1 ratio. From the fourth insertion, after reaching a body weight of approximately 112 kg, 60 fatteners were selected from each group to measure carcass quality and half of them for meat quality evaluation. Moreover, microbiological analyses in feed and colon were performed. The study showed that BioPlus YC probiotics supplementation resulted in a significantly higher count of B. subtilis and B. licheniformis in the feed, a higher count of B. subtilis, B. licheniformis and LAB, as well as a lower count of Enterobacteriaceae, Enterococcus, Clostridium and Bacillus sp. in the mucosa and in the colorectal content of the test pigs. Our work has shown that supplementation with the BioPlus YC probiotic had a positive effect on the production traits of pigs mainly by reducing mortality (2.83%, p = 0.010), lowering feed conversion ratio—FCR (2.59 kg/kg, p = 0.013), better average daily gain—ADG (0.95 kg/day, p = 0.002) and shorter fattening period (77.25 days, p = 0.019) when compared to the control group (4.19%; 2.79 kg/kg; 0.89 kg/day; 92.8 days, respectively). The addition of the specific Bacillus bacteria did not influence carcass and meat characteristics of the test fatteners.


Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1511
Author(s):  
Joseph P. Gulizia ◽  
Kevin M. Downs

Two trials were conducted to determine feed color effects on broiler performance. A completely randomized design was used. Trial 1 included four treatments: control (complete broiler starter diet), red, green, and blue; and Trial 2 included four treatments: control, orange, yellow, and purple. Each trial had 4 treatments with 4 replicates (60 birds/treatment) fed to 240 male Cobb 500 broilers during a 21 d grow out. Data were analyzed using the GLM procedure. In Trial 1, there were no treatment effects on average body weight, body weight gain, and feed consumption (p > 0.05). Adjusted feed conversion for control (1.23) was less than red (1.27; p = 0.001) and green (1.26; p = 0.009), with blue (1.25; p = 0.056) tending to be different during the experimental period. In Trial 2, there were no treatment effects on average body weight, feed consumption, and adjusted feed conversion during this study (p > 0.05). Body weight gain between d 1 to 14 for purple (490.78 g/bird) was more than orange (467 g/bird; p = 0.013) and yellow (461 g/bird; p= 0.004), with control (474 g/bird; p = 0.052) tending to be different. Results indicate that these feed colors had some, albeit limited, influence on broiler performance parameters.


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