Four cases of aggressive MRSA wound infection following head and neck surgery

1997 ◽  
Vol 111 (9) ◽  
pp. 874-876 ◽  
Author(s):  
M. Parton ◽  
N. J. P. Beasley ◽  
G. Harvey ◽  
D. Houghton ◽  
A.S. Jones
Keyword(s):  
Wound Infection ◽  
Head And Neck ◽  
Innominate Artery ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
The Other ◽  
Wound Infections ◽  
Post Mortem ◽  
Mediastinal Abscess ◽  
Fatal Haemorrhage

AbstractFour cases of serious MRSA wound infection following head and neck surgery have been identified. One patient died. At post mortem a mediastinal abscess containing MRSA was found to have eroded into the innominate artery causing fatal haemorrhage. The other three suffered serious wound infections, two requiring further surgery. Once MRSA hadbeen identified they were treated with intravenous teicoplanin and all made a full recovery.

scholarly journals Chemoprophylaxis in Major Head and Neck Surgery

1984 ◽  
Vol 77 (12) ◽  
pp. 1006-1009 ◽  
Author(s):  
C H Raine ◽  
C A Bartzokas ◽  
P M Stell ◽  
A Gallway ◽  
J E Corkill
Keyword(s):  
Head And Neck ◽  
Clavulanic Acid ◽  
Controlled Trial ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
Wound Infections ◽  
Postoperative Sepsis ◽  
Significant Complication

Wound infections are a significant complication following major oncological head and neck surgery. In view of the controversy surrounding the use of chemoprophylaxis a controlled trial was designed. Intravenous Augmentin (amoxycillin and clavulanic acid) was shown to reduce significantly ( P < 0.025) the incidence of postoperative sepsis.

Wound Infection in Head and Neck Surgery: Implications for Perioperative Antibiotic Treatment

1997 ◽  
Vol 76 (11) ◽  
pp. 790-798 ◽  
Author(s):  
Randal S. Weber
Keyword(s):  
Wound Infection ◽  
Head And Neck ◽  
Antibiotic Treatment ◽  
Single Agent ◽  
Cost Effective ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
Beta Lactamase ◽  
Beta Lactam ◽  
Clean Contaminated

Perioperative antibiotic treatment significantly reduces the risk of postoperative wound infection and is cost-effective in clean-contaminated head and neck operations. A clear consensus on the most suitable single agent or combination is, however, lacking. Most surgical wound infections involve both gram-positive and gram-negative aerobes and anaerobes; some organisms may exhibit antibiotic resistance through beta-lactamase production. Comparative trials have indicated that combinations with both aerobic and anaerobic activity provide protection superior to that achieved with single agents active against only aerobic pathogens. Recent results suggest that the beta-lactam/beta-lactamase-inhibitor combination ampi-cillin/sulbactam is cost-effective for perioperative treatment of patients undergoing head and neck surgery.

Postoperative wound infections in head and neck surgery: The current state of antiseptic and antibiotic practices

Oral Oncology ◽  
2021 ◽  
pp. 105361
Author(s):  
Kaleigh A. Stabenau ◽  
Kenneth E. Akakpo ◽  
Jeremy D. Richmon ◽  
Caitlin McMullen ◽  
Andrew J. Holcomb ◽  
...  
Keyword(s):  
Head And Neck ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
Wound Infections ◽  
Postoperative Wound ◽  
Current State

scholarly journals Comparision of Efficacy of Amoxicillin and Ciprofloxacin in Clean Contaminated Ear Surgery During Early Post Operative Period

2018 ◽  
Vol 5 (2) ◽  
pp. 8-10
Author(s):  
Kumud Chapagain ◽  
Rais Pokharel ◽  
Kumud Kumar Kafle ◽  
Bimal Kumar Sinha
Keyword(s):  
Prospective Study ◽  
Wound Infection ◽  
Head And Neck ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
Ear Surgery ◽  
Common Procedure ◽  
Post Operative Period ◽  
Clean Contaminated

Objective: To compare the efficacy of amoxicillin and ciprofloxacin used in clean contaminated ear surgery during the early post operative period.Materials and Methods: It is a longitudinal, prospective study conducted at Department of Otorhinolaryngology and Head and Neck Surgery, TUTH from 1st April 2011 to 30th December 2011.  Patient who underwent clean contaminated ear surgery were followed up on 1st, 3rd and 7th post – operative day (POD) and wounds were inspected for any signs of wound infection.Results: 103 patients who under went various clean contaminated ear surgeries were included in this study. Maximum patients were aged 14-29 years. Ciprofloxacin was prescribed to 80 (77.7%) patients and amoxicillin to 23 (20.3%) patients. Overall wound infection was present on 6.2% (5/80) patients receiving ciprofloxacin and on 4.34% (1/23) patients receiving amoxicillin. The  most common procedure performed was MRM (53%). Wound infection was present in 9% (4/44) of patients undergoing MRM under coverage of ciprofloxacin and on 9% (1/11) patients under coverage of amoxicillin.Conclusion: Though the rate of wound infection was more in patient using ciprofloxacin than amoxicillin but it was not statically significant.Nepalese Journal of ENT Head and Neck Surgery, Vol. 5, No. 2, 2014, page: 8-10

One year review of post-operative wound infection and complications after maxillofacial head and neck surgery

2015 ◽  
Vol 53 (10) ◽  
pp. e66
Author(s):  
A. Rennie ◽  
A. Yuffa ◽  
N. Galligan ◽  
P. Praveen ◽  
T. Martin ◽  
...  
Keyword(s):  
Wound Infection ◽  
Head And Neck ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
One Year ◽  
Operative Wound

Cefotaxime prophylaxis in major non-contaminated head and neck surgery: one-dayvs.seven-day therapy

1993 ◽  
Vol 107 (1) ◽  
pp. 30-32 ◽  
Author(s):  
Erkan Mustafa ◽  
Aslan Tahsin
Keyword(s):  
Antibiotic Prophylaxis ◽  
Wound Infection ◽  
Head And Neck ◽  
Neck Surgery ◽  
Head And Neck Surgery ◽  
Major Surgery ◽  
Double Blind Study ◽  
Antibiotic Administration ◽  
Double Blind ◽  
Perioperative Antibiotic Prophylaxis

AbstractPatients who undergo major surgery of head and neck benefit from perioperative antibiotic prophylaxis. This study was developed to determine if seven days of antibiotic administration would be more effective than one day. A prospective randomized double blind study was designed. Patients were randomly assigned to receive cefotaxime sodium for either 24 hours or seven days. In each case, the drug was administered intramuscularly, beginning one to two hours pre-operatively and continued for the prescribed period. Sixty patients were included in the trial. Of 30 patients assigned to one day of perioperative prophylaxis, wound infection developed in four (13 per cent). Of 30 patients assigned to seven days of perioperative antibiotic prophylaxis, wound infection developed in three (10 per cent) (P>0.05). These data suggest that no beneficial effect from administration of antibiotics for longer than 24 hours post-operatively can be achieved in patients who undergo major head and neck surgery.

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