Retropharyngeal abscess. A rare presentation of nasopharyngeal carcinoma

1999 ◽  
Vol 113 (1) ◽  
pp. 70-72 ◽  
Author(s):  
Martin Wai Pak ◽  
Ka Lai Chan ◽  
Charles Andrew van Hasselt

AbstractEarly symptoms of nasopharyngeal carcinoma (NPC) can often be deceptive and confusing. Most patients with nasopharyngeal carcinoma present at an advanced stage with metastatic cervical nodes present at the time of diagnosis. A deep neck abscess as the presenting feature has not been reported. We report two cases of nasopharyngeal carcinoma which presented with retropharyngeal abscesses and persistent lymphadenopathy. These two patients illustrate that refractory lymphadenopathy, despite adequate treatment of the associated infection, should prompt a search for underlying disease. The relationship between nasopharyngeal carcinoma and retropharyngeal abscess is discussed.

2007 ◽  
Vol 122 (8) ◽  
pp. 867-870 ◽  
Author(s):  
V E S Tan ◽  
J Jeevanan ◽  
B R Lee

AbstractObjective:We report an extremely rare case of nasopharyngeal carcinoma presenting as a lateral neck abscess complicated by endogenous bacterial endophthalmitis. Endogenous bacterial endophthalmitis complicating a neck abscess has not been reported in the recent English literature. We discuss the possible pathophysiology of neck abscess as a presenting feature of nasopharyngeal carcinoma, and the relationship between the parapharyngeal abscess and endogenous bacterial endophthalmitis.Case report:A middle-aged Chinese man presented with a left neck abscess associated with progressive vision deterioration and proptosis of the left eye. Incidentally, his random blood glucose was found to be elevated. Nasal endoscopy also revealed bilateral bogginess in the fossa of Rosenmuller. A diagnosis of left neck abscess with endogenous endophthalmitis associated with underlying diabetes mellitus was made. A computed tomography scan of the neck showed a left parapharyngeal abscess. Incision and drainage of the abscess together with biopsy of the nasopharynx was performed. Due to the non-salvageable condition of the left eye, evisceration was also performed. Pus culture studies from the neck abscess grew Klebsiella pneumoniae, and nasopharyngeal biopsy revealed undifferentiated carcinoma.Conclusion:Nasopharyngeal carcinoma is endemic in South East Asia and can have multiple, varied presentations. Therefore, in this setting, the clinician should have a high index of suspicion, especially in a patient from the Chinese ethnic group.


2011 ◽  
Vol 145 (2_suppl) ◽  
pp. P153-P153
Author(s):  
Sue Rene Soon ◽  
Heng-Wai Yuen

ORL ◽  
2008 ◽  
Vol 70 (4) ◽  
pp. 249-256 ◽  
Author(s):  
Shih-Wei Yang ◽  
Ming-Hsun Lee ◽  
Yun-Shien Lee ◽  
Shu-Huan Huang ◽  
Tai-An Chen ◽  
...  

1998 ◽  
Vol 8 (6) ◽  
pp. 955-959 ◽  
Author(s):  
H. Ojiri ◽  
S. Tada ◽  
M. Ujita ◽  
M. Ariizumi ◽  
C. Ishii ◽  
...  

2021 ◽  
Vol 41 (2) ◽  
pp. 187-191
Author(s):  
Ramesh Omranipour ◽  
Sadaf Alipour ◽  
Bita Eslami

BACKGROUND: Late occurrence of solitary soft tissue upper extremity metastasis of breast cancer is very rare. We hereby present a case of metastasis to the biceps muscle of the ipsilateral arm, detected by a physiotherapist six years after mastectomy. The aim of this report is to highlight the rarity of this presentation, to emphasize the role of the physiotherapist as a member of the multidisciplinary treatment team and the possibility of curative treatment despite the poor prognosis. CASE DESCRIPTION: A 2 * 3 cm well-defined isolated metastasis of breast cancer was diagnosed in the left arm of a 31-year-old woman 6 years after successful treatment of her primary tumor. Tumor characteristics, diagnostic plan, and treatment options are discussed. CONCLUSION: Due to its scarcity, there is a lack of knowledge about the frequency, interval, characteristics, best diagnostic modality, adequate treatment, and prognosis of isolated breast cancer metastasis to the soft tissue, and these can be found out by proper reporting. As an important member of the multidisciplinary team in the care and treatment of breast cancer patients, physiotherapists should be aware of this type of rare presentation.


2012 ◽  
Vol 66 (4) ◽  
pp. 309
Author(s):  
Chan Ho Park ◽  
Jong Kyu Han ◽  
Young Tong Kim ◽  
Hyeong Cheol Shin ◽  
Hyung Hwan Kim ◽  
...  

2020 ◽  
Author(s):  
Chunying Luo ◽  
Min Liu ◽  
Jianwei Zhang ◽  
Guoqiang Su ◽  
Zhonghua Wei

Abstract Background: Many studies have shown that microRNAs play key functions in nasopharyngeal carcinoma proliferation, invasion and metastasis. However, whether the dysregulated level of miRNAs contributes to the metabolic shift in nasopharyngeal carcinoma is not completely understood.Objectives: This study was conducted to explore the expression and function of miR-206 in nasopharyngeal carcinoma.Methods: miR-206 expression level was examined by real-time PCR. miR-206 inhibitor, mimics, and scrambled control were transiently transfected into nasopharyngeal carcinoma cells and their effects on colony formation, glucose uptake, and lactate secretion were observed in vitro. Moreover, the relationship between the levels of miR-206 and HK2 was examined by luciferase reporter and assay western blot.Results: In our study, we reported downregulation of miR-206 expression leads to metabolic change in nasopharyngeal carcinoma cells. miR-206 controls this function by enhancing HK2 expression. The enhancement of aerobic metabolism activity induced by miR-206 leads to the rapid proliferation of nasopharyngeal carcinoma cells.Conclusions: Our data demonstrated that miR-206 was involved in the regulation of Warburg effect in nasopharyngeal carcinoma by suppressing HK2 expression.


2021 ◽  
Vol 29 (3) ◽  
pp. 120-124
Author(s):  
Fulya ÖZER ◽  
Özlem ALKAN ◽  
Şule AKIN

Sign in / Sign up

Export Citation Format

Share Document