Implications for clinical staging of metastatic cutaneous squamous carcinoma of the head and neck based on a multicenter study of treatment outcomes

2005 ◽  
pp. 1
Keyword(s):  
Head And Neck ◽  
Treatment Outcomes ◽  
Multicenter Study ◽  
Squamous Carcinoma ◽  
Clinical Staging

scholarly journals Implications for clinical staging of metastatic cutaneous squamous carcinoma of the head and neck based on a multicenter study of treatment outcomes

Cancer ◽  
2006 ◽  
Vol 106 (5) ◽  
pp. 1078-1083 ◽  
Author(s):  
Jennifer L. Andruchow ◽  
Michael J. Veness ◽  
Gary J. Morgan ◽  
Kan Gao ◽  
Anthony Clifford ◽  
...  
Keyword(s):  
Head And Neck ◽  
Treatment Outcomes ◽  
Multicenter Study ◽  
Squamous Carcinoma ◽  
Clinical Staging

scholarly journals Swedish National Multicenter Study on Head and Neck Cancer of Unknown Primary: Prognostic Factors and Impact of Treatment on Survival

2020 ◽  
Author(s):  
Lars Axelsson ◽  
Erik Holmberg ◽  
Jan Nyman ◽  
Anders Högmo ◽  
Helena Sjödin ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Prognostic Factors ◽  
Head And Neck ◽  
Neck Dissection ◽  
Neck Cancer ◽  
Multicenter Study ◽  
Performance Status ◽  
Cancer Of Unknown Primary ◽  
Unknown Primary ◽  
N Stage

Abstract Introduction Head and neck cancer of unknown primary (HNCUP) is a rare condition whose prognostic factors that are significant for survival vary between studies. No randomized treatment study has been performed thus far, and the optimal treatment is not established. Objective The present study aimed to explore various prognostic factors and compare the two main treatments for HNCUP: neck dissection and (chemo) radiation vs primary (chemo) radiation. Methods A national multicenter study was performed with data from the Swedish Head and Neck Cancer Register (SweHNCR) and from the patients' medical records from 2008 to 2012. Results Two-hundred and sixty HNCUP patients were included. The tumors were HPV-positive in 80%. The overall 5-year survival rate of patients treated with curative intent was 71%. Age (p < 0.001), performance status (p= 0.036), and N stage (p= 0.046) were significant factors for overall survival according to the multivariable analysis. Treatment with neck dissection and (chemo) radiation (122 patients) gave an overall 5-year survival of 73%, and treatment with primary (chemo) radiation (87 patients) gave an overall 5-year survival of 71%, with no significant difference in overall or disease-free survival between the 2 groups. Conclusions Age, performance status, and N stage were significant prognostic factors. Treatment with neck dissection and (chemo) radiation and primary (chemo) radiation gave similar survival outcomes. A randomized treatment study that includes quality of life is needed to establish the optimal treatment.

Head and neck sarcomas: treatment outcomes in a tertiary referral center in Argentina

2021 ◽  
Author(s):  
Alejandro Yanzon ◽  
Natalia Lucia Gomez ◽  
Pedro Picco ◽  
Luis Boccalatte ◽  
Federico Cayol ◽  
...  
Keyword(s):  
Head And Neck ◽  
Treatment Outcomes ◽  
Tertiary Referral ◽  
Tertiary Referral Center ◽  
Referral Center

scholarly journals DNA-Bound Platinum Is the Major Determinant of Cisplatin Sensitivity in Head and Neck Squamous Carcinoma Cells

PLoS ONE ◽  
2013 ◽  
Vol 8 (4) ◽  
pp. e61555 ◽  
Author(s):  
Sanne R. Martens-de Kemp ◽  
Simone U. Dalm ◽  
Fiona M. J. Wijnolts ◽  
Arjen Brink ◽  
Richard J. Honeywell ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Carcinoma ◽  
Carcinoma Cells ◽  
Major Determinant ◽  
Squamous Carcinoma Cells ◽  
Cisplatin Sensitivity

c-myc oncogene copy number in squamous carcinoma of the head and neck

1992 ◽  
Vol 13 (3) ◽  
pp. 168-171 ◽  
Author(s):  
Bruce H. Haughey ◽  
Daniel D. Von Hoff ◽  
Braddford E. Windle ◽  
Geoffrey M. Wahl ◽  
Presley M. Mock
Keyword(s):  
Head And Neck ◽  
Copy Number ◽  
Squamous Carcinoma ◽  
Myc Oncogene

Cisplatin-5-fluorouracil chemotherapy for advanced inoperable squamous carcinoma of the head and neck

1987 ◽  
Vol 9 (6) ◽  
pp. 336-340 ◽  
Author(s):  
Jonas T. Johnson ◽  
David G. Mayernik ◽  
Eugene N. Myers ◽  
Teresa A. Nolan ◽  
Victor L. Schramm ◽  
...  
Keyword(s):  
Head And Neck ◽  
Squamous Carcinoma
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