Discrimination of the Cognitive Profiles of MCI and Depression using the KBNA

Abstract:Objective:The current study sought to determine if the Kaplan-Baycrest Neurocognitive Assessment (KBNA) was capable of discriminating individuals with subjective memory complaints associated with depression from individuals with mild cognitive impairment (MCI).Methods:Scores on 12 subtests of the KBNA were compared for 27 participants with MCI and 28 participants being treated for depression using Bonferroni correct between-group comparisons for each subtest. KBNA subtest scores were corrected for age and education.Results:Significant between-group differences were obtained on six subtests with large effect sizes (Cohen's d) ranging from 1.19 - 1.58. The six subtests involved encoding and delayed episodic memory for verbal and visual information. Using logistic regression analysis, five subtests of the KBNA were able to correctly classify 96.4% of study participants.Conclusion:The results from this preliminary investigation indicate that the KBNA has the potential to serve as a brief and reliable assessment tool capable of distinguishing individuals with subjective memory complaints associated with depression from individuals with MCI in a clinical setting. Limitations of the current study and future research are discussed.

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Subjective Memory Complaints and Mild Cognitive Impairment

European Psychiatry ◽

10.1016/s0924-9338(09)71326-4 ◽

2009 ◽

Vol 24 (S1) ◽

pp. 1-1 ◽

Cited By ~ 2

Author(s):

M. Simoes ◽

L.C. Castro ◽

O. Ribeiro ◽

T. Salgado ◽

C. Paz

Keyword(s):

Cognitive Impairment ◽

Mild Cognitive Impairment ◽

The Elderly ◽

Future Research ◽

Older Individuals ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Cross Sectional ◽

Memory Complaints ◽

Increased Risk

Background:Subjective Memory Complaints (SMC) are common in clinical practice. the clinical significance of these subjective complaints among older individuals is not well understood.Aim:To study and discuss the association between SMC and MCI, underlining the importance of an adequate clinical assessment of SMC in the elderly.Methods:Review of the literature.Results:There is no consistent definition of SMC in the literature. Some prospective studies showed an association with objective memory impairments, conceptualizing SMC as a Pre-Mild Cognitive Impairment. SMC are also currently considered to be a core feature of Mild Cognitive Impairment (MCI). Cross-sectional studies and longitudinal studies showed conflicting results concerning the association between SMC and MCI.Discussion:The understanding of the predictive value of SMC in cognitive decline is still poorly understood. It is important to define criteria aimed to increase specificity of memory complaints, allowing an earlier identification of populations with higher risk of MCI. Future research on this complex association is important to identify SMC individuals at increased risk of conversion to MCI and dementia.

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Prevalence and correlates of subjective memory complaints in Vietnamese adults

International Psychogeriatrics ◽

10.1017/s104161021700254x ◽

2017 ◽

Vol 30 (7) ◽

pp. 1039-1048 ◽

Cited By ~ 4

Author(s):

Oanh L. Meyer ◽

Amanda Leggett ◽

Siwei Liu ◽

Ngoc H. Nguyen

Keyword(s):

Cognitive Impairment ◽

Depressive Symptoms ◽

Cross Sectional Study ◽

Functional Health ◽

Future Research ◽

Regression Analyses ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Cross Sectional ◽

Memory Complaints

ABSTRACTBackground:Low- and middle-income countries such as Vietnam are home to a majority of the world's population with dementia, yet little is known regarding how individuals in these countries perceive memory problems that might be indicative of cognitive impairment. This study examined the prevalence and correlates of subjective memory complaints (SMCs) in Vietnamese adults in Da Nang, Vietnam.Methods:A stratified sample of 600 adults (aged ≥ 55 years) living in Da Nang, Vietnam, and surrounding areas were recruited to participate in a cross-sectional study. Students and faculty from the National Technical Medical College Number 2 administered questionnaires in participants’ homes regarding socio-demographic characteristics, functional health, social support, cognitive and mental health, and SMCs. Descriptive and stepwise regression analyses examined the prevalence and correlates of SMCs.Results:Approximately 64% of the sample reported at least poor memory and 39% said that memory interfered with their daily life at least somewhat. Multivariate regression analyses (adjusted for all covariates) showed that depressive symptoms, cognitive impairment, self-rated health and pain, and material hardship were associated with SMCs.Conclusions:Prevalence of SMCs as well as depressive symptoms was high in this Vietnamese population. Although future research using more detailed measures of subjective memory and which include longitudinal data are required, the need for physicians to routinely assess Vietnamese patients for depression, SMCs, and cognitive impairment may be warranted.

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Subjective memory complaints predict baseline but not future cognitive function over three years: results from the Western Australia Memory Study

International Psychogeriatrics ◽

10.1017/s1041610218001072 ◽

2018 ◽

Vol 31 (04) ◽

pp. 513-525 ◽

Cited By ~ 4

Author(s):

Hamid R. Sohrabi ◽

Michael Weinborn ◽

Christoph Laske ◽

Kristyn A. Bates ◽

Daniel Christensen ◽

...

Keyword(s):

Cognitive Function ◽

Community Dwelling ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Cognitive Changes ◽

Distinctive Features ◽

Clinical Assessments ◽

Memory Complaints ◽

Study Participants ◽

Single Question

ABSTRACTBackground:This study investigated the characteristics of subjective memory complaints (SMCs) and their association with current and future cognitive functions.Methods:A cohort of 209 community-dwelling individuals without dementia aged 47–90 years old was recruited for this 3-year study. Participants underwent neuropsychological and clinical assessments annually. Participants were divided into SMCs and non-memory complainers (NMCs) using a single question at baseline and a memory complaints questionnaire following baseline, to evaluate differential patterns of complaints. In addition, comprehensive assessment of memory complaints was undertaken to evaluate whether severity and consistency of complaints differentially predicted cognitive function.Results:SMC and NMC individuals were significantly different on various features of SMCs. Greater overall severity (but not consistency) of complaints was significantly associated with current and future cognitive functioning.Conclusions:SMC individuals present distinctive features of memory complaints as compared to NMCs. Further, the severity of complaints was a significant predictor of future cognition. However, SMC did not significantly predict change over time in this sample. These findings warrant further research into the specific features of SMCs that may portend subsequent neuropathological and cognitive changes when screening individuals at increased future risk of dementia.

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“Shall We Dance?” Older Adults’ Perspectives on the Feasibility of a Dance Intervention for Cognitive Function

Journal of Aging and Physical Activity ◽

10.1123/japa.2017-0203 ◽

2018 ◽

Vol 26 (4) ◽

pp. 553-560

Author(s):

Cecilie Thøgersen-Ntoumani ◽

Anthony Papathomas ◽

Jonathan Foster ◽

Eleanor Quested ◽

Nikos Ntoumanis

Keyword(s):

Older Adults ◽

Cognitive Function ◽

Memory Loss ◽

Future Research ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Social Dance ◽

Memory Complaints ◽

Semistructured Interviews ◽

Dance Intervention

We explored perceptions of social dance as a possible intervention to improve cognitive function in older adults with subjective memory complaints. A total of 30 participants (19 females; mean age = 72.6 years; SD = 8.2) took part in the study. This included 21 participants who had self-reported subjective memory complaints and nine spouses who noticed spousal memory loss. Semistructured interviews were conducted, and a thematic analysis was used to analyze the data. Three main themes were constructed: (a) dance seen as a means of promoting social interaction; (b) chronic illness as a barrier and facilitator to participation; and (c) social dance representing nostalgic connections to the past. Overall, the participants were positive about the potential attractiveness of social dance to improve cognitive and social functioning and other aspects of health. In future research, it is important to examine the feasibility of a social dance intervention among older adults with subjective memory complaints.

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An ERP study on facial emotion processing in young people with subjective memory complaints

Scientific Reports ◽

10.1038/s41598-021-90861-9 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Vanesa Perez ◽

Ruth Garrido-Chaves ◽

Mario Perez-Alarcón ◽

Tiago O. Paiva ◽

Matias M. Pulopulos ◽

...

Keyword(s):

Young People ◽

Early Stage ◽

Emotion Processing ◽

Affective State ◽

Event Related Potential ◽

Facial Emotion ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Memory Complaints ◽

Facial Emotion Processing

AbstractSubjective memory complaints (SMCs) are commonly related to aging, but they are also presented by young adults. Their neurophysiological mechanisms are not thoroughly understood, although some aspects related to affective state have been mentioned. Here, we investigated whether facial emotion processing is different in young people with (n = 41) and without (n = 39) SMCs who were exposed to positive, negative, and neutral faces, by recording the event-related potential (ERP) activity. From the ERP activity, the N170 (an index of face processing) and the LPP (an index of motivated attention) components were extracted. Regarding the N170, results showed less amplitude for positive and neutral faces in the participants with SMCs than in those without SMCs. Moreover, women with SMCs displayed longer latencies for neutral faces than women without SMCs. No significant differences were found between the groups in the LPP component. Together, our findings suggest deficits in an early stage of facial emotion processing in young people with SMCs, and they emphasize the importance of further examining affective dimensions.

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Z-score neurofeedback, heart rate variability biofeedback, and brain coaching for older adults with memory concerns

Restorative Neurology and Neuroscience ◽

10.3233/rnn-201053 ◽

2020 ◽

pp. 1-29

Author(s):

Kyle D. Meeuwsen ◽

Kayleah M. Groeneveld ◽

Linda A. Walker ◽

Anna M. Mennenga ◽

Rachel K. Tittle ◽

...

Keyword(s):

Quality Of Life ◽

Boot Camp ◽

Relative Power ◽

Z Score ◽

Subjective Memory Complaints ◽

Subjective Memory ◽

Memory Complaints ◽

Anxiety Depression

Background: The three-month, multidomain Memory Boot Camp program incorporates z-score neurofeedback (NFB), heart rate variability (HRV) biofeedback, and one-on-one coaching to teach memory skills and encourage behavior change in diet, sleep, physical fitness, and stress reduction. Objective: This prospective trial evaluates the Memory Boot Camp program for adults ages 55 to 85 with symptoms of Mild Cognitive Impairment (MCI) and subjective memory complaints. Methods: Participants were evaluated via the Montreal Cognitive Assessment (MoCA), NeuroTrax Global Cognitive Index, measures of anxiety, depression, sleep, quality of life, quantitative electroencephalography (QEEG), and HRV parameters at four timepoints: baseline, pre-program, post-program, and follow-up. The trial included a three-month waiting period between baseline and pre-program, such that each participant acted as their own control, and follow-up took place six months after completion of the program. Results: Participants’ MoCA scores and self-reported measures of anxiety, depression, sleep quality, and quality of life improved after treatment, and these changes were maintained at follow-up. Physiological changes in HRV parameters after treatment were not significant, however, breathing rate and QEEG parameters were improved at post-program and maintained at follow-up. Finally, participants’ improvement in MoCA score over the treatment period was correlated with their improvement in two brain oscillation parameters targeted by the z-score NFB protocol: relative power of delta and relative power of theta. Conclusions: Trial results suggest that the Memory Boot Camp program is a promising treatment strategy for older adults with symptoms of MCI and subjective memory complaints.

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