Orofacial dyskinesia: caused by antidepressants?

1991 ◽  
Vol 3 (1) ◽  
pp. 1-4
Author(s):  
A.R. Van Gool ◽  
R.C. Van Der Mast ◽  
P. Moleman

SummaryA case report is presented of a 72 year old woman, who has been treated for a depression with amitriptyline. During the treatment an orofacial dyskinesia develloped. Data in the literature concerning a possible link between the manifestation of orofacial dyskinesia and treatment with antidepressants were mainly found to be case reports. A closer study of the total in all of 25 case reports reveals that the antidepressant is often at most one of more possible determinants of the movement disorder. Particularly, it was frequently noted that patients were treated with other drugs or that the use of other drugs was not specified. A controverse exists in the literature whether or not a so called spontaneous orofacial dyskinesia is found in high frequency in elderly people. For clinical practice the advice is given that, in case an orofacial dyskinesia arises during antidepressant treatment, attention should be paid to other provoking factors in the first place.

Homeopathy ◽  
2021 ◽  
Author(s):  
Jürgen Pannek ◽  
Susanne Pannek-Rademacher

Abstract Background Homeopathy is frequently and successfully used in daily clinical practice, so there is a need for well-documented case reports that illustrate its effectiveness. For this reason, we present a case in which homeopathy was used to treat an ankle and lower leg for spontaneous acute swelling and redness. Case Report A 54-year-old man presented with recurrence of a swollen left ankle and lower leg, which had previously been treated by conventional medicine. After case taking, a homeopathic treatment with Apis mellifica 200c led to a fast improvement. The patient was free of symptoms within 24 hours and has remained so for 3 years. Conclusion Homeopathic treatment with Apis mellifica led to a fast and long-lasting improvement of an acute ankle swelling and reddening that had recurred after conventional medical therapy of similar symptoms.


2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Quevedo-Florez Leonardo Alexander ◽  
Montenegro-Apraez Alvaro Andrés ◽  
Aguiar-Martinez Leonar Giovanni ◽  
Hernández Juan Carlos ◽  
Cortés-Tascón Juan David

Pneumothorax is the entry of air into the virtual space between the visceral and the parietal pleurae, which can occur spontaneously or to a greater extent in a traumatic way. In daily clinical practice it is frequent to find injuries that generate traumatic pneumothorax that is ipsilateral to the lesion. However, there are case reports of contralateral pneumothorax that occurred in procedures such as insertion of pacemakers, or in cases of pneumonectomy. The following is the case report of a 37-year-old man who was admitted with a sharp wound to the right paravertebral region who developed a left haemopneumothorax due to a tangential course of the injuring agent. Adequate clinical judgment was followed, and several imaging studies were carried out, leading to the diagnosis of traumatic pneumothorax that was contralateral to the described injury.


2017 ◽  
Vol 7 (1) ◽  
pp. 50-55
Author(s):  
Md Abdul Wohab Khan ◽  
Abdus Salam Arif

Case reports represent the oldest and most familiar form of medical communication. It is one of the best ways for the beginners to get familiar with scholarly writing. It is the time-honored vehicle for medical teaching. It is also the foundational 'building block' of scientific inquiry. Unfortunately from late 1970s in scientific community there was a tendency to see the case report as least important and a 'second class' publication. The authors tried to find out how this 'fertile seeds' were cultivated and valued by the scientific community. Articles on case reports were collected consecutively by daisy chaining from web and published journals. Many logical arguments are found in favor of encouraging in writing and publishing case reports. There are also issues to be addressed further. Diversified criteria and stylescan be followed. Uniqueness is not the only principle, any information which someone find useful and beneficial in clinical practice can be presented as case report. Facts in a case report can be considered as one of the weakest evidence and should not be considered as anecdotal information. To make others aware of unusual presentationsor complications;case report is the rapid and effective means of communication.Anwer Khan Modern Medical College Journal Vol. 7, No. 1: Jan 2016, P 50-55


2019 ◽  
Vol 9 (3) ◽  
pp. 57-60
Author(s):  
James Pearce ◽  
Paul Simpson

Clinical case reports play an important role in supporting evidence-based paramedicine. When research on a topic is limited and there is no robust evidence, a case report may be the best available, especially for rare or unusual presentations or in novel clinical practice. Case reports in paramedicine journals are common. However, adherence to the published consensus-based reporting guideline is rare, which may weaken the evidence arising from this body of case report literature. There is a need for greater awareness of the structured reporting guideline for case reports, and for the development of a paramedicine-specific extension. The objectives of this paper are to: describe the current state of case reports in paramedicine; promote the adoption of an internationally accepted, consensus-based reporting guideline; and propose an extension to that guideline, adapted to the unique characteristics of prehospital practice.


2020 ◽  
Vol 33 (2) ◽  
pp. e100112
Author(s):  
Cuizhen Zhu ◽  
Ran Bi ◽  
Yuliang Hu ◽  
Hui Zhou ◽  
Daomin Zhu ◽  
...  

Restless legs syndrome (RLS) is a common sleep-related movement disorder characterised by an uncomfortable urge to move the legs that occurs during periods of inactivity. Although there have been many case reports on antipsychotic-induced RLS, ziprasidone has never been reported as a cause of RLS. We present a case of a female patient with schizophrenia who presented with symptoms of RLS following the administration of high doses of ziprasidone added to quetiapine and valproate. The patient’s symptoms of RLS occurred following the administration and titration of ziprasidone to 160 mg, and were relieved upon reducing the dose to 120 mg/day. Other potential causative medications and differential diagnoses that could have caused similar symptoms were excluded. Clinicians should be aware of the potential for ziprasidone-induced RLS. Dopamine and serotonin interaction could be the mechanism underlying ziprasidone-induced RLS.


2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
A. Justine Landi ◽  
Robert Burkes

Drug-induced thrombocytopenia is a poorly understood, yet common phenomenon widely encountered in clinical practice. We present a case of suspected levofloxacin-induced thrombocytopenia, a rare side effect of a ubiquitous antibiotic, in a patient without similar effect to ciprofloxacin. This report builds upon other isolated case reports of fluoroquinolone-induced thrombocytopenia and demonstrates our algorithmic approach to the issue as well as a literature review pertaining to fluoroquinolone-induced thrombocytopenia.


2007 ◽  
Vol 20 (1) ◽  
pp. 71
Author(s):  
Young Bok Lee ◽  
Jong Taek Park ◽  
Ja Youn Jeon ◽  
Kwang Ho Lee

2019 ◽  
Vol 98 (7) ◽  
pp. 291-296

Introduction: Fournier’s gangrene is a rare but fast deteriorating and serious condition with high mortality. In most cases, it is characterized as necrotizing fasciitis of the perineum and external genitals. Amyand’s hernia is a rare condition where the appendix is contained in the sac of an inguinal hernia. Inflammatory alterations in the appendix account only for 0.1 % of the cases when Amyand’s hernia is verified. Fournier’s gangrene as a complication of a late diagnosis of appendicitis located in the inguinal canal is described in the literature as rare case reports. Case report: The case report of a 70-year-old patient with Fournier’s gangrene resulting from gangrenous appendicitis of Amyand’s hernia. Conclusion: Fournier’s gangrene as a complication of Amyand’s hernia is a rare condition. Only sporadic case reports thereof can be found in the literature. Because of the rarity of this pathology and the lack of randomized controlled studies, it is difficult to determine the optimal treatment according to the principles of evidence-based medicine. An appropriate approach for this condition appears to be the combination of guidelines developed in Amyand’s therapy according to Losanoff and Basson, along with the recommended “gold standard” therapy for Fournier’s gangrene. This means early and highly radical surgical debridement, adequate antibiotic therapy and intensive care.


2019 ◽  
Vol 98 (4) ◽  
pp. 178-180

Cavernous hemangiomas are benign tumours of mesodermal origin. Even though various localizations of hemangioma have been described in the literature, its occurrence in the greater omentum is very rare. Only symptomatic hemangiomas are indicated for surgical treatment. There are case reports presenting resection or surgical removal of the greater omentum with hemangioma because of mechanical syndrome, consumption coagulopathy, bleeding, infection or suspicion of a malignancy. This article presents a case report of a patient operated on for a suspicion of carcinomatosis of the greater omentum. Histological examination found hemangiomatosis in the resected greater omentum.


2020 ◽  
Vol 1 (2) ◽  
pp. 38-44
Author(s):  
Irina V. Vakhlova ◽  
Anastasia D. Kazachina ◽  
Olga A. Beglyanina

Background. In the international clinical practice there have been occasional reports of phenylketonuria (PKU) and cystic fibrosis (CF) found simultaneously in the same patient. Both PKU and CF are the inherited disorders characterized by autosomal recessive type of inheritance. Currently the combination of two or more inherited disorders in one patient is considered to be a clinical rarity.Case description. This is a clinical case of two genetic disorders, CF and PKU, combined in a 5-year old patient who had been followed up since birth. Owing to implementation of neonatal screening for inherited and congenital diseases into clinical practice, during the first month of life the infant was diagnosed with CF (diagnostically significant elevation of immunoreactive trypsin [IRT] at the initial [163.2 ng/mL] and repeat testing on day 21 of life [138.7 ng/mL]) and PKU (phenylalanine [PA] level 15.9 mg/dL). Both disorders have been confirmed by genetic tests, i.e., homozygous DelF508 mutation was found in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and P281L mutation in the phenylalanine hydroxylase (PAH) gene was also present in homozygous state. Child’s parents strictly adhered to dietary and treatment recommendations. By the age of 5 years the child developed symptoms of neurological disorder and disorder of the respiratory system, cognitive impairment and delay in speech development, subclinical epileptiform activity with high risk of epilepsy, and chronic inflammation of the respiratory tract.Conclusion. This case report demonstrates the important role of neonatal screening in early diagnosis and timely start of therapy, and underscores the importance of continuous medication in such genetic disorders as CF and PKU. On the whole, such approach brings about a relative preservation of functioning of the most affected organs and systems. By the age of 5 years the child does not form bronchiectases, shows no signs of chronic hypoxia, nutritional deficiency or pronounced neurologic deficit, and is at low risk for the development of autism spectrum disorder. At the same time, the larger scale and longer-term observations are required in order to make the unequivocal conclusions about the prognosis of these diseases under conditions of modern-day medical follow-up.


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