An Infant With Mucolipidosis-II And an Atretic orifice of the Left Coronary Artery

2009 ◽  
Vol 20 (1) ◽  
pp. 97-99 ◽  
Author(s):  
Ana Siles ◽  
Grant A. Mitchell ◽  
Nagib S. Dahdah
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Coronary Artery ◽  
Left Coronary Artery ◽  
Color Doppler ◽  
Type Ii ◽  
Retrograde Flow ◽  
Cardiac Enzymes ◽  
Selective Coronary Angiography ◽  
Mucolipidosis Ii

AbstractA one-month-old boy, with type-II mucolipidosis, presented with congestive heart failure and elevated cardiac enzymes. The atretic nature of the orifice of the left coronary artery was revealed by retrograde flow on color Doppler and selective coronary angiography. Type-II mucolipidosis and atresia of the left coronary artery are rare. To the best of our knowledge, this is the first report of their combined occurence, suggesting a possible causal relationship.

scholarly journals Non-compaction cardiomyopathy with diffuse left coronary artery fistulae as a rare cause of congestive heart failure

2013 ◽  
Vol 34 (1) ◽  
pp. 12-12 ◽  
Author(s):  
Joachim Wilhelm ◽  
Konstantin Heinroth ◽  
Dietrich Stoevesandt ◽  
Karl Werdan ◽  
Alexander Plehn
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Coronary Artery ◽  
Left Coronary Artery

Endurance training restores peritoneal macrophage function in post-MI congestive heart failure rats

2007 ◽  
Vol 102 (5) ◽  
pp. 2033-2039 ◽  
Author(s):  
M. L. Batista ◽  
R. V. T. Santos ◽  
E. M. Oliveira ◽  
M. C. L. Seelaender ◽  
L. F. B. P. Costa Rosa
Keyword(s):  
Heart Failure ◽  
Congestive Heart Failure ◽  
Coronary Artery ◽  
Endurance Training ◽  
Left Coronary Artery ◽  
Citrate Synthase ◽  
Metabolic Effects ◽  
Moderate Intensity ◽  
Sedentary Group ◽  
Tnf Α

Congestive heart failure (CHF) induces a state of immune activation, and peritoneal macrophages (Mφs) may play an important role in the development and progression of one such condition. Moderate endurance training modulates peritoneal Mφ function. We evaluated the effect of endurance training on different stages of the phagocytic process and in the production of interleukin-6 (IL-6), interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) after LPS stimulation. Either ligation of the left coronary artery or Sham operations were performed in adult Wistar rats. After 4 wk, control (Sham operated) and MI (ligation of the left coronary artery) animals were randomly assigned to either a sedentary (Sham-operated sedentary, n = 7 and MI sedentary, n = 10) or a trained group (Sham-operated trained, n = 8 and MI trained, n = 8). Trained rats ran on a treadmill (0% grade at 13–20 m/min) for 60 min/day, 5 days/wk, for 8–10 wk, whereas sedentary rats had only limited activity. Training increased maximal oxygen uptake normalized for body weight (ml·kg−1·min−1), as well as skeletal muscle citrate synthase maximal activity, when compared with sedentary groups. The resident and total cell number, the chemotaxis index, and the production of TNF-α stimulated by LPS were significantly higher in the MI sedentary group when compared with the Sham sedentary group. Moderate endurance training reversed these alterations promoted by post-MI. These results demonstrate that moderate intensity exercise training modulates peritoneal Mφ function and induces beneficial metabolic effects in rats with post-MI CHF.

Right and left coronary artery to left ventricle fistula detected by color Doppler flow mapping

1987 ◽  
Vol 114 (4) ◽  
pp. 890-894 ◽  
Author(s):  
Toshio Nishikimi ◽  
Hisao Oku ◽  
Kazuyoshi Hirota ◽  
Kayoko Murai ◽  
Takahiko Kawarabayashi ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Left Ventricle ◽  
Left Coronary Artery ◽  
Color Doppler ◽  
Flow Mapping ◽  
Doppler Flow ◽  
Color Doppler Flow

scholarly journals Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure

2003 ◽  
Vol 285 (4) ◽  
pp. H1576-H1581 ◽  
Author(s):  
Fraser D. Russell ◽  
Deborah Meyers ◽  
Andrew J. Galbraith ◽  
Nick Bett ◽  
Istvan Toth ◽  
...  
Keyword(s):  
Heart Failure ◽  
Coronary Artery Disease ◽  
Congestive Heart Failure ◽  
Coronary Artery ◽  
Pulmonary Artery ◽  
Femoral Artery ◽  
Aortic Root ◽  
Femoral Vein ◽  
Urotensin Ii ◽  
Artery Disease

Human urotensin-II (hU-II) is the most potent endogenous cardiostimulant identified to date. We therefore determined whether hU-II has a possible pathological role by investigating its levels in patients with congestive heart failure (CHF). Blood samples were obtained from the aortic root, femoral artery, femoral vein, and pulmonary artery from CHF patients undergoing cardiac catheterization and the aortic root from patients undergoing investigative angiography for chest pain who were not in heart failure. Immunoreactive hU-II (hU-II-ir) levels were determined with radioimmunoassay. hU-II-ir was elevated in the aortic root of CHF patients (230.9 ± 68.7 pg/ml, n = 21; P < 0.001) vs. patients with nonfailing hearts (22.7 ± 6.1 pg/ml, n = 18). This increase was attributed to cardiopulmonary production of hU-II-ir because levels were lower in the pulmonary artery (38.2 ± 6.1 pg/ml, n = 21; P < 0.001) than in the aortic root. hU-II-ir was elevated in the aortic root of CHF patients with nonischemic cardiomyopathy (142.1 ± 51.5 pg/ml, n = 10; P < 0.05) vs. patients with nonfailing hearts without coronary artery disease (27.3 ± 12.4 pg/ml, n = 7) and CHF patients with ischemic cardiomyopathy (311.6 ± 120.4 pg/ml, n = 11; P < 0.001) vs. patients with nonfailing hearts and coronary artery disease (19.8 ± 6.6 pg/ml, n = 11). hU-II-ir was significantly higher in the aortic root than in the pulmonary artery and femoral vein, with a nonsignificant trend for higher levels in the aortic root than in the femoral artery. The findings indicated that hU-II-ir is elevated in the aortic root of CHF patients and that hU-II-ir is cleared at least in part from the microcirculation.

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