Oxidative Cleavage-Based Three-Dimensional DNA Biosensor for Ratiometric Detection of Hypochlorous Acid and Myeloperoxidase

Author(s):  
Jing Wang ◽  
Jia-Yi Ma ◽  
Dong-Xia Wang ◽  
Bo Liu ◽  
Xiao Jing ◽  
...  
Small ◽  
2014 ◽  
Vol 10 (17) ◽  
pp. 3560-3567 ◽  
Author(s):  
Yi Zhou ◽  
Wenbo Pei ◽  
Chenyuan Wang ◽  
Jixin Zhu ◽  
Jiansheng Wu ◽  
...  

RSC Advances ◽  
2014 ◽  
Vol 4 (104) ◽  
pp. 59961-59964 ◽  
Author(s):  
Fang Ma ◽  
Mingtai Sun ◽  
Kui Zhang ◽  
Yajun Zhang ◽  
Houjuan Zhu ◽  
...  

2019 ◽  
Vol 11 (32) ◽  
pp. 4157-4164 ◽  
Author(s):  
Chen Jiang ◽  
Yuewei Yao ◽  
Chuilian Kong ◽  
Jiaqi Du ◽  
Jingjing Meng ◽  
...  

An anthracene-based fluorescence probe B-ClO that exhibited excellent selectivity and sensitivity for colorimetric and ratiometric detection of ClO− in 80% aqueous DMF solution has been designed and developed.


2015 ◽  
Vol 3 (24) ◽  
pp. 4805-4813 ◽  
Author(s):  
Rong Tian ◽  
Xiaojun Chen ◽  
Nan Jiang ◽  
Ning Hao ◽  
Lin Xu ◽  
...  

An Hg2+-switched DNA biosensor using a three dimensional ordered macroporous polyaniline–platinum platform and a G-rich sequence recognition probe was developed, with the detection limit of 8.7 × 10−14 M.


2013 ◽  
Vol 702 ◽  
pp. 72-78 ◽  
Author(s):  
Young Jo Kim ◽  
John E. Jones ◽  
Hao Li ◽  
Helen Yampara-Iquise ◽  
Guolu Zheng ◽  
...  

2019 ◽  
Vol 75 (10) ◽  
pp. 1405-1416
Author(s):  
Daniel E. Vicentes ◽  
Ricaurte Rodríguez ◽  
Patricia Ochoa ◽  
Justo Cobo ◽  
Christopher Glidewell

A concise and efficient synthesis of a series of amino-substituted benzimidazole–pyrimidine hybrids has been developed, starting from the readily available N 4-(2-aminophenyl)-6-methoxy-5-nitrosopyrimidine-2,4-diamine. In each of N 5-benzyl-6-methoxy-4-(2-phenyl-1H-benzo[d]imidazol-1-yl)pyrimidine-2,5-diamine, C25H22N6O, (I), 6-methoxy-N 5-(4-methoxybenzyl)-4-[2-(4-methoxyphenyl)-1H-benzo[d]imidazol-1-yl]pyrimidine-2,5-diamine, C27H26N6O3, (III), 6-methoxy-N 5-(4-nitrobenzyl)-4-[2-(4-nitrophenyl)-1H-benzo[d]imidazol-1-yl]pyrimidine-2,5-diamine, C25H20N8O5, (IV), the molecules are linked into three-dimensional framework structures, using different combinations of N—H...N, N—H...O, C—H...O, C—H...N and C—H...π hydrogen bonds in each case. Oxidative cleavage of 6-methoxy-N 5-(4-methylbenzyl)-4-[2-(4-methylphenyl)-1H-benzo[d]imidazol-1-yl]pyrimidine-2,5-diamine, (II), with diiodine gave 6-methoxy-4-[2-(4-methylphenyl)-1H-benzo[d]imidazol-1-yl]pyrimidine-2,5-diamine, which crystallized as a monohydrate, C19H18N6O·H2O, (V), and reaction of (V) with trifluoroacetic acid gave two isomeric products, namely N-{5-amino-6-methoxy-6-[2-(4-methylphenyl)-1H-benzo[d]imidazol-1-yl]pyrimidin-2-yl}-2,2,2-trifluoroacetamide, which crystallized as an ethyl acetate monosolvate, C21H17F3N6O2·C4H8O2, (VI), and N-{2-amino-6-methoxy-4-[2-(4-methylphenyl)-1H-benzo[d]imidazol-1-yl]pyrimidin-5-yl}-2,2,2-trifluoroacetamide, which crystallized as a methanol monosolvate, C21H17F3N6O2·CH4O, (VIIa). For each of (V), (VI) and (VIIa), the supramolecular assembly is two-dimensional, based on different combinations of O—H...N, N—H...O, N—H...N, C—H...O and C—H...π hydrogen bonds in each case. Comparisons are made with some related structures.


2021 ◽  
pp. 106728
Author(s):  
Xiaojia Zhao ◽  
Zicheng Zhu ◽  
Rong Zou ◽  
Lingyun Wang ◽  
Hang Gong ◽  
...  

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