Enzymatic Polymerization of Poly(glycerol-1,8-octanediol-sebacate): Versatile Poly(glycerol sebacate) Analogues that Form Monocomponent Biodegradable Fiber Scaffolds

2020 ◽  
Vol 21 (8) ◽  
pp. 3197-3206 ◽  
Author(s):  
Kening Lang ◽  
Somdatta Bhattacharya ◽  
Zhuoyuan Ning ◽  
Regina J. Sánchez-Leija ◽  
Michael T. K. Bramson ◽  
...  
2002 ◽  
Vol 6 (2) ◽  
pp. 209-222 ◽  
Author(s):  
Shiro Kobayashi ◽  
Hiroshi Uyama

2021 ◽  
pp. 118234
Author(s):  
Azin Adibi ◽  
James Kim ◽  
Jorge Mok ◽  
Christian Lenges ◽  
Leonardo Simon ◽  
...  

2020 ◽  
Vol 8 (1) ◽  
pp. 4
Author(s):  
Devan L. Puhl ◽  
Jessica L. Funnell ◽  
Derek W. Nelson ◽  
Manoj K. Gottipati ◽  
Ryan J. Gilbert

Electrospinning is a fabrication technique used to produce nano- or micro- diameter fibers to generate biocompatible, biodegradable scaffolds for tissue engineering applications. Electrospun fiber scaffolds are advantageous for neural regeneration because they mimic the structure of the nervous system extracellular matrix and provide contact guidance for regenerating axons. Glia are non-neuronal regulatory cells that maintain homeostasis in the healthy nervous system and regulate regeneration in the injured nervous system. Electrospun fiber scaffolds offer a wide range of characteristics, such as fiber alignment, diameter, surface nanotopography, and surface chemistry that can be engineered to achieve a desired glial cell response to injury. Further, electrospun fibers can be loaded with drugs, nucleic acids, or proteins to provide the local, sustained release of such therapeutics to alter glial cell phenotype to better support regeneration. This review provides the first comprehensive overview of how electrospun fiber alignment, diameter, surface nanotopography, surface functionalization, and therapeutic delivery affect Schwann cells in the peripheral nervous system and astrocytes, oligodendrocytes, and microglia in the central nervous system both in vitro and in vivo. The information presented can be used to design and optimize electrospun fiber scaffolds to target glial cell response to mitigate nervous system injury and improve regeneration.


Author(s):  
Ting Yang ◽  
Xuejun Cui ◽  
Yanbing Kao ◽  
Hongyan Wang ◽  
Jihong Wen

1999 ◽  
Vol 144 (1) ◽  
pp. 237-246 ◽  
Author(s):  
Shiro Kobayashi ◽  
Hiroshi Uyama

2017 ◽  
Vol 232 ◽  
pp. 25-30 ◽  
Author(s):  
Madis Harjo ◽  
Arko Kesküla ◽  
Kaur Leemets ◽  
Mahdi Safaei Khorram ◽  
Rando Saar ◽  
...  

2006 ◽  
Vol 50 (1) ◽  
pp. 31-32 ◽  
Author(s):  
Masayasu Kuwahara ◽  
Yoshiyuki Suto ◽  
Satoshi Minezaki ◽  
Rina Kitagata ◽  
Jun-ichi Nagashima ◽  
...  

Langmuir ◽  
2009 ◽  
Vol 25 (19) ◽  
pp. 11390-11405 ◽  
Author(s):  
Zengwei Guo ◽  
Heinz Rüegger ◽  
Reinhard Kissner ◽  
Takashi Ishikawa ◽  
Martin Willeke ◽  
...  

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