Prominent Contribution of Hydrogen Peroxide to Intracellular Reactive Oxygen Species Generated upon Exposure to Naphthalene Secondary Organic Aerosols

2020 ◽  
Vol 7 (3) ◽  
pp. 171-177
Author(s):  
Fobang Liu ◽  
Maria G. Saavedra ◽  
Julie A. Champion ◽  
Kathy K. Griendling ◽  
Nga L. Ng
Keyword(s):  
Reactive Oxygen Species ◽  
Hydrogen Peroxide ◽  
Secondary Organic Aerosols ◽  
Organic Aerosols ◽  
Reactive Oxygen ◽  
Intracellular Reactive Oxygen Species ◽  
Oxygen Species

scholarly journals Reactive oxygen species formed in aqueous mixtures of secondary organic aerosols and mineral dust influencing cloud chemistry and public health in the Anthropocene

2017 ◽  
Vol 200 ◽  
pp. 251-270 ◽  
Author(s):  
Haijie Tong ◽  
Pascale S. J. Lakey ◽  
Andrea M. Arangio ◽  
Joanna Socorro ◽  
Christopher J. Kampf ◽  
...  
Keyword(s):  
Public Health ◽  
Reactive Oxygen Species ◽  
Secondary Organic Aerosols ◽  
Mineral Dust ◽  
Organic Aerosols ◽  
Reactive Oxygen ◽  
Oh Radicals ◽  
Oxygen Species ◽  
Aqueous Mixtures ◽  
Cloud Chemistry

Mineral dust and secondary organic aerosols (SOA) account for a major fraction of atmospheric particulate matter, affecting climate, air quality and public health. How mineral dust interacts with SOA to influence cloud chemistry and public health, however, is not well understood. Here, we investigated the formation of reactive oxygen species (ROS), which are key species of atmospheric and physiological chemistry, in aqueous mixtures of SOA and mineral dust by applying electron paramagnetic resonance (EPR) spectrometry in combination with a spin-trapping technique, liquid chromatography-tandem mass spectrometry (LC-MS/MS), and a kinetic model. We found that substantial amounts of ROS including OH, superoxide as well as carbon- and oxygen-centred organic radicals can be formed in aqueous mixtures of isoprene, α-pinene, naphthalene SOA and various kinds of mineral dust (ripidolite, montmorillonite, kaolinite, palygorskite, and Saharan dust). The molar yields of total radicals were ∼0.02–0.5% at 295 K, which showed higher values at 310 K, upon 254 nm UV exposure, and under low pH (<3) conditions. ROS formation can be explained by the decomposition of organic hydroperoxides, which are a prominent fraction of SOA, through interactions with water and Fenton-like reactions with dissolved transition metal ions. Our findings imply that the chemical reactivity and aging of SOA particles can be enhanced upon interaction with mineral dust in deliquesced particles or cloud/fog droplets. SOA decomposition could be comparably important to the classical Fenton reaction of H2O2 with Fe2+ and that SOA can be the main source of OH radicals in aqueous droplets at low concentrations of H2O2 and Fe2+. In the human respiratory tract, the inhalation and deposition of SOA and mineral dust can also lead to the release of ROS, which may contribute to oxidative stress and play an important role in the adverse health effects of atmospheric aerosols in the Anthropocene.

scholarly journals Reactive Oxygen Species Production from Secondary Organic Aerosols: The Importance of Singlet Oxygen

2019 ◽  
Vol 53 (15) ◽  
pp. 8553-8562 ◽  
Author(s):  
Alessandro Manfrin ◽  
Sergey A. Nizkorodov ◽  
Kurtis T. Malecha ◽  
Gordon J. Getzinger ◽  
Kristopher McNeill ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Singlet Oxygen ◽  
Reactive Oxygen Species Production ◽  
Secondary Organic Aerosols ◽  
Organic Aerosols ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Species Production

scholarly journals Reactive Oxygen Species Formed by Secondary Organic Aerosols in Water and Surrogate Lung Fluid

2018 ◽  
Author(s):  
Haijie Tong ◽  
Pascale S. J. Lakey ◽  
Andrea M. Arangio ◽  
Joanna Socorro ◽  
Fangxia Shen ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Secondary Organic Aerosols ◽  
Organic Aerosols ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Lung Fluid

Connecting the Oxidative Potential of Secondary Organic Aerosols with Reactive Oxygen Species in Exposed Lung Cells

2019 ◽  
Vol 53 (23) ◽  
pp. 13949-13958 ◽  
Author(s):  
Pratiti Home Chowdhury ◽  
Quanfu He ◽  
Raanan Carmieli ◽  
Chunlin Li ◽  
Yinon Rudich ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Secondary Organic Aerosols ◽  
Organic Aerosols ◽  
Reactive Oxygen ◽  
Lung Cells ◽  
Oxygen Species ◽  
Oxidative Potential
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