Targeting Tn-Antigen-Positive Human Tumors with a Recombinant Human Macrophage Galactose C-Type Lectin

2021 ◽  
Author(s):  
François Bulteau ◽  
Michel Thépaut ◽  
Maxime Henry ◽  
Amandine Hurbin ◽  
Laetitia Vanwonterghem ◽  
...  
Keyword(s):  
Human Tumors ◽  
Human Macrophage ◽  
Tn Antigen

scholarly journals Calorimetric Analysis of the Interplay between Synthetic Tn Antigen-Presenting MUC1 Glycopeptides and Human Macrophage Galactose-Type Lectin

Biochemistry ◽  
2021 ◽  
Vol 60 (7) ◽  
pp. 547-558
Author(s):  
Donella M. Beckwith ◽  
Forrest G. FitzGerald ◽  
Maria C. Rodriguez Benavente ◽  
Elizabeth R. Mercer ◽  
Anna-Kristin Ludwig ◽  
...  
Keyword(s):  
Human Macrophage ◽  
Tn Antigen ◽  
Calorimetric Analysis ◽  
Antigen Presenting

EXPERIMENTAL STUDY OF THE EFFICACY OF L-LYSINE-A-OXIDASE TRICHODERMA CF. AUREOVIRIDE RIFAI ON MODELS OF XENOGRAFTS OF HUMAN TUMORS IN ATHYMIC MICE AND EVALUATION OF SYNERGISM WITH CISPLATIN OR TOPOISOMERASE INHIBITORS

2017 ◽  
Vol 63 (3) ◽  
pp. 497-505
Author(s):  
Vadim Pokrovskiy ◽  
Yelena Lukasheva ◽  
Nikolay Chernov ◽  
Yelena Treshchalina
Keyword(s):  
Experimental Study ◽  
Life Expectancy ◽  
Therapeutic Benefit ◽  
Human Tumors ◽  
Lymphocytic Leukemia ◽  
Antitumor Drugs ◽  
Athymic Mice ◽  
Lewis Lung ◽  
Topoisomerase Inhibitors ◽  
Inhibition Of Growth

The effectiveness of L-lysine-alpha oxidase Trichoderma cf. Aureoviride Rifai BKMF-4268D (LO) on models of subcutaneous xenografts of human tumors in athymic mice as well as the effectiveness of combination therapy with known antitumor drugs: cisplatin, irinotecan, etoposide on models of P388 lymphocytic leukemia, Lewis lung (LLC) and B16 melanoma was evaluated. The intraperitoneal injection of LO in a discrete regime at doses of 150-75-75-75-75 E/kg demonstrated inhibition of growth of all studied xenografts of human tumors in athymic mice. The combination of irinotecan+LO on the LLC model gave a significant summative therapeutic benefit with an increase in mouse life expectancy up to 35%. Cisplatin and LO realized a significant (p

Erythropoietin Directly Affects Human Macrophage Functionality

2018 ◽  
Vol 19 (11) ◽  
pp. 902-909 ◽  
Author(s):  
Olga V. Melashchenko ◽  
Maxim E. Meniailo ◽  
Vladimir V. Malashchenko ◽  
Natalya D. Gazatova ◽  
Andrei G. Goncharov ◽  
...  
Keyword(s):  
Human Macrophage

Gelatin‐Hyaluronan Click‐Crosslinked Cryogels Elucidate Human Macrophage Invasion Behavior

2021 ◽  
pp. 2008400
Author(s):  
Laura C. Bahlmann ◽  
Alexander E. G. Baker ◽  
Chang Xue ◽  
Sophie Liu ◽  
Moritz Meier‐Merziger ◽  
...  
Keyword(s):  
Human Macrophage ◽  
Invasion Behavior
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