Mechanistic Studies on the Palladium-Catalyzed Cross Dehydrogenative Coupling of P(O)–H Compounds with Terminal Alkynes: Stereochemistry and Reactive Intermediates

2015 ◽  
Vol 34 (20) ◽  
pp. 5095-5098 ◽  
Author(s):  
Jia Yang ◽  
Tieqiao Chen ◽  
Yongbo Zhou ◽  
Shuang-Feng Yin ◽  
Li-Biao Han
Keyword(s):  
Reactive Intermediates ◽  
Terminal Alkynes ◽  
Mechanistic Studies ◽  
Dehydrogenative Coupling ◽  
Palladium Catalyzed

Palladium-catalyzed dehydrogenative coupling of terminal alkynes with secondary phosphine oxides

2015 ◽  
Vol 51 (17) ◽  
pp. 3549-3551 ◽  
Author(s):  
Jia Yang ◽  
Tieqiao Chen ◽  
Yongbo Zhou ◽  
Shuangfeng Yin ◽  
Li-Biao Han
Keyword(s):  
Reaction Mechanism ◽  
Palladium Acetate ◽  
Secondary Phosphine ◽  
Terminal Alkynes ◽  
Phosphine Oxides ◽  
Dehydrogenative Coupling ◽  
Palladium Catalyzed ◽  
High Yields

The palladium-catalyzed dehydrogenative coupling of alkynes with secondary phosphine oxides is developed. Thus, in the presence of a silver additive, palladium acetate could efficiently catalyze the dehydrocoupling of secondary phosphine oxides with a variety of alkynes to produce the corresponding alkynylphosphine oxides in high yields. A reaction mechanism is proposed.

Palladium-Catalyzed Dehydrogenative Coupling Reaction of Terminal Alkynes with Unactivated Alkenes

2017 ◽  
Vol 65 (1) ◽  
pp. 117-121 ◽  
Author(s):  
Akira Yada ◽  
Shoki Nishi ◽  
Yuta Sato ◽  
Sakina Ichinoseki ◽  
Masahiro Murakami
Keyword(s):  
Coupling Reaction ◽  
Terminal Alkynes ◽  
Dehydrogenative Coupling ◽  
Palladium Catalyzed

Mechanistic studies on the palladium-catalyzed cross-dehydrogenative coupling of 4-phenoxy-2-coumarins: experimental and computational insights

2018 ◽  
Vol 47 (17) ◽  
pp. 6049-6053 ◽  
Author(s):  
Aisling M. Prendergast ◽  
Zhihan Zhang ◽  
Zhenyang Lin ◽  
Gerard P. McGlacken
Keyword(s):  
Experimental Studies ◽  
Mechanistic Studies ◽  
Dehydrogenative Coupling ◽  
Palladium Catalyzed

Computational and experimental studies suggest that intramolecular dehydrogenative coupling of 4-phenoxy-2-coumarins proceeds via two concerted metallation-deprotonation (CMD) events.

Iron-mediated cross dehydrogenative coupling (CDC) of terminal alkynes with benzylic ethers and alkanes

2011 ◽  
Vol 55 (1) ◽  
pp. 50-54 ◽  
Author(s):  
Shi-Kai Xiang ◽  
Bo Zhang ◽  
Li-He Zhang ◽  
YuXin Cui ◽  
Ning Jiao
Keyword(s):  
Terminal Alkynes ◽  
Dehydrogenative Coupling
Sign in / Sign up

Export Citation Format

Share Document