Reaction-Based Off–On Near-infrared Fluorescent Probe for Imaging Alkaline Phosphatase Activity in Living Cells and Mice

2017 ◽  
Vol 9 (8) ◽  
pp. 6796-6803 ◽  
Author(s):  
Yi Tan ◽  
Ling Zhang ◽  
Ka Ho Man ◽  
Raoul Peltier ◽  
Ganchao Chen ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Fluorescent Probe ◽  
Alkaline Phosphatase Activity ◽  
Near Infrared ◽  
Living Cells

A turn-on near-infrared fluorescent probe for visualization of endogenous alkaline phosphatase activity in living cells and zebrafish

The Analyst ◽  
2021 ◽  
Author(s):  
Xiao Pang ◽  
Yaqian Li ◽  
Qiujun Lu ◽  
Ziqi Ni ◽  
Zile Zhou ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Fluorescent Probe ◽  
Alkaline Phosphatase Activity ◽  
Near Infrared ◽  
Living Cells ◽  
Turn On ◽  
Living Organisms

Alkaline phosphatase (ALP) is an essential hydrolase and widely distributed in living organisms.

Near-infrared mito-specific fluorescent probe for ratiometric detection and imaging of alkaline phosphatase activity with high sensitivity

2019 ◽  
Vol 7 (3) ◽  
pp. 443-450 ◽  
Author(s):  
Qian Zhang ◽  
Shasha Li ◽  
Caixia Fu ◽  
Yuzhe Xiao ◽  
Peng Zhang ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Fluorescent Probe ◽  
Alkaline Phosphatase Activity ◽  
Near Infrared ◽  
High Sensitivity ◽  
Cyanine Dye ◽  
Intracellular Imaging ◽  
Ratiometric Detection ◽  
Ratiometric Fluorescent Probe

A NIR ratiometric fluorescent probe based on cyanine dye was developed for detecting and intracellular imaging of ALP activity with high sensitivity.

Biocompatible fluorescent probe for detecting mitochondrial alkaline phosphatase activity in live cells

2020 ◽  
Vol 212 ◽  
pp. 112043 ◽  
Author(s):  
Sabina Khatun ◽  
Shayeri Biswas ◽  
Arun Kumar Mahanta ◽  
Manu M. Joseph ◽  
Murukan S. Vidyalekshmi ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Fluorescent Probe ◽  
Alkaline Phosphatase Activity ◽  
Live Cells

An activity-based fluorescent probe and its application for differentiating alkaline phosphatase activity in different cell lines

2020 ◽  
Vol 56 (87) ◽  
pp. 13323-13326
Author(s):  
Yong He ◽  
Junli Yu ◽  
Xiangzi Hu ◽  
Shumei Huang ◽  
Lili Cai ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Fluorescent Probe ◽  
Cell Lines ◽  
Alkaline Phosphatase Activity

An activity-based fluorescent probe with the characteristics of AIE + ESIPT has been reported for differentiating the alkaline phosphatase activity in different cell lines.

Real-time imaging of alkaline phosphatase activity of diabetes in mice via a near-infrared fluorescent probe

2021 ◽  
Author(s):  
Wen-Xin Wang ◽  
Wen-Li Jiang ◽  
Hong Guo ◽  
Yongfei Li ◽  
Chun-Yan Li
Keyword(s):  
Alkaline Phosphatase ◽  
Real Time ◽  
Fluorescent Probe ◽  
Alkaline Phosphatase Activity ◽  
Near Infrared ◽  
Water Soluble ◽  
Alp Activity ◽  
Diabetes In Mice ◽  
Real Time Image ◽  
Time Image

A novel water-soluble near-infrared fluorescent probe named QX-P with simple synthesis is developed for detecting ALP. The probe can not only visualize ALP activity in four cell lines, but also real-time image ALP activity of diabetes in mice.

Photoelectrochemical Analysis of Alkaline Phosphatase Activity in Single Living Cells

The Analyst ◽  
2021 ◽  
Author(s):  
Nina Wang ◽  
Rongrong Pan ◽  
Li-Na Ji ◽  
Dechen Jiang ◽  
Hong-Yuan Chen
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Alkaline Phosphatase Activity ◽  
Living Cells ◽  
Tin Oxides ◽  
Single Living Cells ◽  
Single Living

Conventional photoelectrochemical (PEC) analysis mostly utilizes the photoactive material modified planar indium tin oxides (ITOs) to obtain photocurrent responses for the measurement of analytes in the solution. In this work,...

A novel near-infrared fluorescent probe for detecting intracellular alkaline phosphatase and imaging of living cells

2019 ◽  
Vol 7 (8) ◽  
pp. 1284-1291 ◽  
Author(s):  
Longbin Xu ◽  
Xu He ◽  
Yibing Huang ◽  
Pinyi Ma ◽  
Yanxiao Jiang ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Fluorescent Probe ◽  
Near Infrared ◽  
Living Cells ◽  
Design Synthesis

Design, synthesis and application of a fluorescent probe with a novel near-infrared fluorophore for in vivo imaging of alkaline phosphatase.

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