One-Pot Enzymatic–Chemical Cascade Route for Synthesizing Aromatic α-Hydroxy Ketones

ACS Catalysis ◽  
2021 ◽  
pp. 2808-2818
Author(s):  
Lei Wang ◽  
Wei Song ◽  
Binju Wang ◽  
Yan Zhang ◽  
Xin Xu ◽  
...  
Keyword(s):  
One Pot ◽  
ChemInform ◽  
2009 ◽  
Vol 40 (4) ◽  
Author(s):  
Shao-Bo Yang ◽  
Feng-Feng Gan ◽  
Guo-Ju Chen ◽  
Peng-Fei Xu

2012 ◽  
Vol 9 (1) ◽  
pp. 131-136
Author(s):  
P. Sunil Kumar ◽  
K. M. Lokanatha Rai

A facile method for a mild single pot reductive cleavage of 1,2-oxazines toγ-hydroxy ketones was developed using zinc and aqueous ammonium chloride as the reagent in methanol. The reaction involves the reduction of N-O bond of the oxazine and the hydrolysis of the resulting 1,4-iminoalcohol.


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