Tuning the Self-Assembling of Pyridinium Cationic Lipids for Efficient Gene Delivery into Neuronal Cells

The self-assembling and gene transfer capabilities of monodisperse amphiphilic aminoglucoside–cyclodextrin conjugates depend on the amino disposition at the glycationic head.

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Ionic liquids with thioether motifs as synthetic cationic lipids for gene delivery

Chemical Communications ◽

10.1039/c7cc03235h ◽

2017 ◽

Vol 53 (59) ◽

pp. 8328-8331 ◽

Cited By ~ 5

Author(s):

Jamie C. Gaitor ◽

Lauren M. Paul ◽

Melissa M. Reardon ◽

Taha Hmissa ◽

Samuel Minkowicz ◽

...

Keyword(s):

Ionic Liquids ◽

Gene Delivery ◽

Click Chemistry ◽

Gene Transfection ◽

Cationic Lipids ◽

Efficient Gene

Novel lipidic ionic liquids with imidazolium headgroups (red), thioether linkers (black), and two hydrophobic tails (blue) as efficient gene transfection vectors, synthesized via thiol–yne click chemistry.

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Synthesis of a novel series of cationic lipids that can act as efficient gene delivery vehicles through systematic heterocyclic substitution of cholesterol derivatives

Gene Therapy ◽

10.1038/sj.gt.3301471 ◽

2001 ◽

Vol 8 (11) ◽

pp. 855-863 ◽

Cited By ~ 44

Author(s):

H Gao ◽

K M Hui

Keyword(s):

Gene Delivery ◽

Cationic Lipids ◽

Efficient Gene ◽

Delivery Vehicles ◽

Gene Delivery Vehicles

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Novel Cholesterol-Based Cationic Lipids as Transfecting Agents of DNA for Efficient Gene Delivery

International Journal of Molecular Sciences ◽

10.3390/ijms16035666 ◽

2015 ◽

Vol 16 (12) ◽

pp. 5666-5681 ◽

Cited By ~ 14

Author(s):

Jia Ju ◽

Meng-Lei Huan ◽

Ning Wan ◽

Hai Qiu ◽

Si-Yuan Zhou ◽

...

Keyword(s):

Gene Delivery ◽

Cationic Lipids ◽

Efficient Gene

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Charge-switching amino acids-based cationic lipids for efficient gene delivery

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2015.11.001 ◽

2015 ◽

Vol 25 (24) ◽

pp. 5677-5681 ◽

Cited By ~ 5

Author(s):

Li-Ting Zheng ◽

Wen-Jing Yi ◽

Qiang Liu ◽

Rong-Chuan Su ◽

Zhi-Gang Zhao

Keyword(s):

Amino Acids ◽

Gene Delivery ◽

Cationic Lipids ◽

Efficient Gene

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Dendritic Cationic Lipids with Highly Charged Headgroups for Efficient Gene Delivery

Bioconjugate Chemistry ◽

10.1021/bc050310c ◽

2006 ◽

Vol 17 (4) ◽

pp. 877-888 ◽

Cited By ~ 45

Author(s):

Kai K. Ewert ◽

Heather M. Evans ◽

Nathan F. Bouxsein ◽

Cyrus R. Safinya

Keyword(s):

Gene Delivery ◽

Cationic Lipids ◽

Efficient Gene

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Development of new self-assembled cationic amino liposomes for efficient gene delivery

Biomaterials Science ◽

10.1039/d0bm00331j ◽

2020 ◽

Vol 8 (11) ◽

pp. 3021-3025 ◽

Cited By ~ 2

Author(s):

Yihang Wu ◽

Yue Xiong ◽

Ling Wang ◽

Quanming Zhou ◽

Linxian Li ◽

...

Keyword(s):

Gene Delivery ◽

Transfection Efficiency ◽

Self Assembling ◽

Efficient Gene ◽

Self Assembled ◽

Low Cytotoxicity

A library of lipidoids self-assembling to liposomes exhibits excellent transfection efficiency in HEK 293T cells and mESCs with low cytotoxicity.

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α-Tocopherol-anchored gemini lipids with delocalizable cationic head groups: Effect of spacer length on DNA compaction and transfection properties

Organic & Biomolecular Chemistry ◽

10.1039/d1ob00475a ◽

2021 ◽

Author(s):

Mallikarjun Gosangi ◽

Venkatesh Ravula ◽

Hithavani Rapaka ◽

Srilakshmi V Patri

Keyword(s):

Gene Delivery ◽

Cationic Lipids ◽

Spacer Length ◽

Dna Compaction ◽

Structure Activity ◽

Head Groups ◽

Efficient Gene ◽

Delivery Vehicles ◽

Systematic Structure

Understanding the role of structural units in cationic lipids used for gene delivery is essential in designing efficient gene delivery vehicles. Herein we report a systematic structure-activity investigation on the...

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