scholarly journals Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor

2018 ◽  
Vol 140 (26) ◽  
pp. 8228-8235 ◽  
Author(s):  
Matthew T. Eddy ◽  
Zhan-Guo Gao ◽  
Philip Mannes ◽  
Nilkanth Patel ◽  
Kenneth A. Jacobson ◽  
...  
Keyword(s):  
Membrane Proteins ◽  
Adenosine Receptor ◽  
A2a Adenosine Receptor ◽  
Allosteric Coupling

scholarly journals Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor

Cell ◽  
2018 ◽  
Vol 172 (1-2) ◽  
pp. 68-80.e12 ◽  
Author(s):  
Matthew T. Eddy ◽  
Ming-Yue Lee ◽  
Zhan-Guo Gao ◽  
Kate L. White ◽  
Tatiana Didenko ◽  
...  
Keyword(s):  
Adenosine Receptor ◽  
Intracellular Signaling ◽  
Drug Binding ◽  
A2a Adenosine Receptor ◽  
Allosteric Coupling

scholarly journals Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor

2021 ◽  
pp. 184-196
Author(s):  
Matthew T. Eddy ◽  
Ming-Yue Lee ◽  
Zhan-Guo Gao ◽  
Kate L. White ◽  
Tatiana Didenko ◽  
...  
Keyword(s):  
Adenosine Receptor ◽  
Intracellular Signaling ◽  
Drug Binding ◽  
A2a Adenosine Receptor ◽  
Allosteric Coupling

Ligand-Based Virtual Screening Using Tailored Ensembles: A Prioritization Tool for Dual A2A Adenosine Receptor Antagonists / Monoamine Oxidase B Inhibitors

2016 ◽  
Vol 22 (21) ◽  
pp. 3082-3096 ◽  
Author(s):  
Aliuska Morales Helguera ◽  
Yunierkis Perez-Castillo ◽  
M. Natália D.S. Cordeiro ◽  
Eduardo Tejera ◽  
César Paz-y-Miño ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Monoamine Oxidase ◽  
Adenosine Receptor ◽  
Monoamine Oxidase B ◽  
Receptor Antagonists ◽  
A2a Adenosine Receptor

scholarly journals Constitutive activity of the A2A adenosine receptor and compartmentalised cyclic AMP signalling fine-tune noradrenaline release

2012 ◽  
Vol 8 (4) ◽  
pp. 677-692 ◽  
Author(s):  
Edin Ibrisimovic ◽  
Helmut Drobny ◽  
Qiong Yang ◽  
Thomas Höfer ◽  
Stefan Boehm ◽  
...  
Keyword(s):  
Cyclic Amp ◽  
Noradrenaline Release ◽  
Adenosine Receptor ◽  
Constitutive Activity ◽  
A2a Adenosine Receptor ◽  
Fine Tune
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