Background: Emotional divorce refers to a situation in which the emotional relationship, support, passion, warmth, attention, love, and intimacy between couples (husband & wife) decline or diminish. Such conditions lead to an unaffectionate marital life to the point that the couples are only together under one roof. Accordingly, the present study aimed to explore the role of attachment styles and spiritual intelligence in predicting emotional divorce in women. Methods: This study employed a descriptive-correlational design. The research population included all women filing for divorce who were referred to marriage counseling and couple therapy centers in districts 5 and 6 in Tehran City, Iran, in 2020. In total, 400 women who met the inclusion criteria were selected as the study participants using voluntary response and convenience sampling techniques. The required data were collected by the Emotional Divorce Scale, the Adult Attachment Scale, and the Self-Report Measure of Spiritual Intelligence. The collected data were analyzed using the multiple regression analysis method in SPSS V. 22. Results: The obtained results suggested a significant positive relationship between the anxious-avoidant attachment style and emotional divorce (P<0.01). Furthermore, there was a significant negative relationship between spiritual intelligence and emotional divorce; the higher the spiritual intelligence, the lower the emotional divorce (P=0.02). Accordingly, spiritual intelligence and anxious-avoidant attachment style can predict emotional divorce (Multiple Regressions= -0.58). Conclusion: The present study data suggested that premarital education and counseling before spouse selection help in examining the personality traits of the parties. Moreover, paying attention to the role of health professionals, such as family counselors, psychologists, and psychiatric nurses in providing premarital counseling and education to couples and emphasizing the role of spiritual intelligence and attachment styles may prevent emotional separation and divorce among couples.