Differences Between Golden Hamsters (Mesocricetus auratus) and Norway Rats (Rattus norvegicus) in Preference for the Sole Diet That They Are Eating.

2005 ◽  
Vol 119 (1) ◽  
pp. 8-13 ◽  
Author(s):  
Bennett G. Galef ◽  
Elaine E. Whiskin
2017 ◽  
Vol 47 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Claudia Dantas COMANDOLLI-WYREPKOWSKI ◽  
Iryna GRAFOVA ◽  
Maricleide de Farias NAIFF ◽  
Maurizio AVELLA ◽  
Gennaro GENTILE ◽  
...  

ABSTRACT Current treatment of cutaneous leishmaniasis (CL) relies mainly on pentavalent antimonials salts and second-line drugs include pentamidine and amphotericin B, but these therapies have side effects and require parenteral administration. The aim of this work was to evaluate the topical formulations containing pentamidine isethionate (PI) in the experimental treatment of cutaneous leishmaniasis (CL). Golden hamsters (Mesocricetus auratus) were infected in the nose with Leishmania (Leishmania) amazonensis. Six treatment groups received different topical treatments of anhydrous or hydrating emulsions, for a maximum of 10 days, with an application of 50 mg day-1. After treatment tissue samples of lesions were evaluated by histology, transmission electron microscopy and biopsy cultivation. Compared with untreated group, topical treatment with hydrating emulsion with 10% PI and usnic acid (ACE5AU) showed significantly decrease in volume lesion (P= 0.028) on 20th day after the end of the treatment with reduction of 27.37%. Topical treatment with anhydrous emulsion with 10% PI and usnic acid (ACPU) reduces parasite burden in Golden hamsters. This study demonstrated the potential of topical treatment to reduce the number of parasites that could be combined with others drugs and to have a faster and more effective treatment of cutaneous leishmaniasis.


1984 ◽  
Vol 77 (4) ◽  
pp. 759-762 ◽  
Author(s):  
Jiří Vaněček ◽  
Ladislav Janský ◽  
Helena Illnerová ◽  
Klaus Hoffmann

1986 ◽  
Vol 96 (3) ◽  
pp. 467-473 ◽  
Author(s):  
A. P. Buckle

SUMMARYThe anticoagulant rodenticide flocoumafen was tested against warfarin-resistant Norway rats (Rattus norvegicus Berk.) infesting farm buildings. Complete control was obtained in 10–21 days (mean 14·2 days) in six treatments in which baits poisoned with 0·005% flocoumafen were maintained, in surplus, until rats ceased to feed from them. A further six treatments, in which the application of poisoned bait was restricted to periodic placements of 50 g, were also completely successful in 15–30 days (mean 21·0 days). Less poisoned bait was used in the restricted flocoumafen treatments than in the unrestricted treatments but the time taken to control the rat infestations was significantly longer.


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