This book describes Interpersonal Psychotherapy–Adolescent Skills Training (IPT-AST), an interpersonally oriented depression prevention program for adolescents. The program developed from an interest in developing and studying a depression prevention program for youth who are experiencing depressive symptoms but do not yet qualify for a diagnosis of depression. The IPT-AST program is a predominantly group-based intervention that teaches communication and interpersonal problem-solving skills to improve relationships and prevent the development of depression. The book provides a detailed description of the IPT-AST program so readers can implement groups in different settings. In addition, there are chapters that outline key issues related to implementation of IPT-AST, including selecting adolescents to participate in group, conducting IPT-AST in schools and other diverse settings, working with adolescents at varying levels of risk for depression, and dealing with common clinical issues. Finally, the book outlines the research that has been conducted on this depression prevention program.