scholarly journals Phase I and pharmacological study of the new topoisomerase I inhibitor GI147211, using a daily x 5 intravenous administration

1996 ◽  
Vol 73 (6) ◽  
pp. 744-750 ◽  
Author(s):  
CJH Gerrits ◽  
GJ Creemers ◽  
JHM Schellens ◽  
P Wissel ◽  
AS Planting ◽  
...  
Keyword(s):  
Phase I ◽  
Intravenous Administration ◽  
Topoisomerase I ◽  
Pharmacological Study ◽  
Topoisomerase I Inhibitor

A phase I clinical and pharmacological study of oral 9-nitrocamptothecin, a novel water-insoluble topoisomerase I inhibitor

1998 ◽  
Vol 9 (1) ◽  
pp. 36-44 ◽  
Author(s):  
Claire F Verschraegen ◽  
Ethan A Natelson ◽  
Beppino C Giovanella ◽  
John J Kavanagh ◽  
Andrzej P Kudelka ◽  
...  
Keyword(s):  
Phase I ◽  
Topoisomerase I ◽  
Pharmacological Study ◽  
Topoisomerase I Inhibitor

scholarly journals Phase I and pharmacokinetics study of topotecan, a new topoisomerase I inhibitor

1993 ◽  
Vol 4 (8) ◽  
pp. 673-678 ◽  
Author(s):  
J. Verweij ◽  
B. Lund ◽  
J. Beijnen ◽  
A. Planting ◽  
M. de Boer-Dennert ◽  
...  
Keyword(s):  
Phase I ◽  
Topoisomerase I ◽  
Topoisomerase I Inhibitor ◽  
Pharmacokinetics Study

A phase I clinical and pharmacokinetic study of the topoisomerase I inhibitor topotecan (SK&F 104864) given as an intravenous bolus every 21 days

1992 ◽  
Vol 3 (4) ◽  
pp. 337-346 ◽  
Author(s):  
James G Wall ◽  
Howard A Burris ◽  
Daniel D Von Hoff ◽  
Gladys Rodriguez ◽  
Rayna Kneuper-Hall ◽  
...  
Keyword(s):  
Phase I ◽  
Pharmacokinetic Study ◽  
Topoisomerase I ◽  
Intravenous Bolus ◽  
Topoisomerase I Inhibitor

Abstract 4517: Plasma and tumor pharmacokinetics of IV LMP744, a novel indenoisoquinoline topoisomerase I inhibitor, in a canine phase I study

2015 ◽  
Author(s):  
Julie L. Eiseman ◽  
Julianne Holleran ◽  
David L. McCormick ◽  
Miguel Muzzio ◽  
Joseph M. Covey ◽  
...  
Keyword(s):  
Phase I ◽  
Phase I Study ◽  
Topoisomerase I ◽  
Topoisomerase I Inhibitor ◽  
Tumor Pharmacokinetics

Phase I and pharmacokinetic study of edotecarin, a novel topoisomerase I inhibitor, administered once every 3 weeks in patients with solid tumors

2005 ◽  
Vol 58 (2) ◽  
pp. 173-182 ◽  
Author(s):  
Yasuhide Yamada ◽  
Tomohide Tamura ◽  
Noboru Yamamoto ◽  
Tatsu Shimoyama ◽  
Yutaka Ueda ◽  
...  
Keyword(s):  
Phase I ◽  
Solid Tumors ◽  
Pharmacokinetic Study ◽  
Topoisomerase I ◽  
Topoisomerase I Inhibitor

scholarly journals Phase I/pharmacokinetic study of the topoisomerase I inhibitor GG211 administered as a 21-day continuous infusion

1999 ◽  
Vol 10 (3) ◽  
pp. 339-344 ◽  
Author(s):  
J.P. Stevenson ◽  
D. DeMaria ◽  
J. Sludden ◽  
S.B. Kaye ◽  
L. Paz-Ares ◽  
...  
Keyword(s):  
Phase I ◽  
Continuous Infusion ◽  
Pharmacokinetic Study ◽  
Topoisomerase I ◽  
Topoisomerase I Inhibitor
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