scholarly journals Overestimation of the classification accuracy of a biomarker for assessing heavy alcohol use

2017 ◽  
Vol 23 (11) ◽  
pp. 2114-2115 ◽  
Author(s):  
M W Hattab ◽  
S L Clark ◽  
E J C G van den Oord
Keyword(s):  
Alcohol Use ◽  
Classification Accuracy ◽  
Heavy Alcohol ◽  
Heavy Alcohol Use

Predictors of Sexual Intimate Partner Violence Perpetration Among Men: A Prospective Analysis

2021 ◽  
pp. 088626052198973
Author(s):  
Hailee K. Dunn ◽  
Deborah N. Pearlman ◽  
Madeline C. Montgomery ◽  
Lindsay M. Orchowski
Keyword(s):  
Intimate Partner Violence ◽  
Alcohol Use ◽  
Young Adulthood ◽  
Partner Violence ◽  
Teen Dating Violence ◽  
Intimate Partner ◽  
Heavy Alcohol ◽  
Peer Approval ◽  
Sexual Intimate Partner Violence ◽  
Heavy Alcohol Use

Research demonstrates that both peer socialization and underage drinking play a significant role in teen dating violence. However, less is known about the lasting effects of these risk factors on boys’ ability to form healthy romantic relationships as they get older. The present study examined whether boys who perceived their peers would respect them more for having sex and those who engaged in past year heavy alcohol use would be more likely to perpetrate sexual intimate partner violence (IPV) in young adulthood compared to boys who did not endorse perceived peer approval for sex or report past year heavy drinking. Analyses were conducted using a sample of boys ( n = 1,189) from Waves I and III of the National Longitudinal Study of Adolescent to Adult Health (Add Health). A logistic regression was conducted to assess the relationship between perceived peer approval to have sex and heavy alcohol use at Wave I and sexual IPV at Wave III, after adjusting for demographic factors and other correlates of sexual IPV at Wave I, including age, race/ethnicity, sexual initiation in adolescence, parental attachment, annual family income, and neighborhood poverty. Boys who believed they would gain peer respect by having sex and boys who reported getting drunk in the last 12 months, regardless of how often, were significantly more likely to report sexual IPV in young adulthood compared to boys who did not endorse either of these factors. Targeting boys’ perceived peer norms regarding sexual activity and heavy alcohol use may therefore be especially important for preventing sexual IPV later in life.

scholarly journals Heavy alcohol consumption in individuals with HIV infection: Effects on neuropsychological performance

2005 ◽  
Vol 11 (1) ◽  
pp. 70-83 ◽  
Author(s):  
JOHANNES C. ROTHLIND ◽  
TANYA M. GREENFIELD ◽  
ANNE V. BRUCE ◽  
DIETER J. MEYERHOFF ◽  
DEREK L. FLENNIKEN ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Executive Functioning ◽  
Hiv Infection ◽  
Synergistic Effects ◽  
Heavy Drinking ◽  
Heavy Alcohol ◽  
Heavy Drinkers ◽  
Heavy Alcohol Use ◽  
Active Alcohol

Higher rates of alcohol use have been reported in HIV+ individuals compared to the general population. Both heavy alcohol use and HIV infection are associated with increased risk of neuropsychological (NP) impairment. We examined effects of heavy active alcohol use and HIV on NP functioning in a large sample of community-residing HIV+ individuals and HIV− controls. The four main study groups included 72 HIV− light/non-drinkers, 70 HIV− heavy drinkers (>100 drinks per month), 70 HIV+ light/non-drinkers, and 56 HIV+ heavy drinkers. The heavy drinking group was further subdivided to assess effects of the heaviest levels of active alcohol use (>6 drinks per day) on NP functioning. A comprehensive NP battery was administered. Multivariate analysis of covariance was employed to examine the effect of HIV and alcohol on NP functioning after adjusting for group differences in age and estimated premorbid verbal intellectual functioning. The analyses identified main effects of heavy drinking and HIV on NP function, with greatest effects involving the contrast of HIV+ heavy drinkers and the HIV− light drinkers. Synergistic effects of heaviest current drinking and HIV infection were identified in analyses of motor and visuomotor speed. Supplementary analyses also revealed better NP function in the HIV+ group with antiretroviral treatment (ART) and lower level of viral burden, a finding that was consistent across levels of alcohol consumption. Finally, heavy alcohol use and executive functioning difficulties were associated with lower levels of self-reported medication adherence in the HIV+ group. The findings suggest that active heavy alcohol use and HIV infection have additive adverse effects on NP function, that they may show synergistic effects in circumstances of very heavy active alcohol use, and that heavy drinking and executive functioning may mediate health-related behaviors in HIV disease. (JINS, 2005, 11, 70–83.)

scholarly journals Preoperative C-Reactive Protein to Albumin Ratio and Oral Health in Oral Squamous Cell Carcinoma Patients

2020 ◽  
Author(s):  
Arvi Keinänen ◽  
Johanna Uittamo ◽  
Magdalena Marinescu-Gava ◽  
Satu Kainulainen ◽  
Johanna Snäll
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Health ◽  
Alcohol Use ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Early Mortality ◽  
C Reactive Protein ◽  
Heavy Alcohol ◽  
Reactive Protein ◽  
Heavy Alcohol Use

Abstract Background The C-reactive protein to albumin (CRP/alb) ratio can predict early mortality of a hospitalized patient. We evaluated factors that influence the preoperative CRP/alb ratio in oral squamous cell carcinoma (OSCC) patients and in particular clarified the role of oral health to this ratio. Materials and Methods Data from surgically treated OSCC patients were collected retrospectively. Patient 3-month mortality was recorded. The outcome variables were preoperative CRP/alb ratio, CRP level, and alb level. The studied predictors were total number of teeth, periodontal stability, marginal bone loss, tumour stage, T-class, lymph node status, and site. The statistical significance of age, sex, comorbidity combination of age and disease history (Charlson Comorbidity Index [CCI]), smoking, and alcohol history for outcome variables were evaluated.Results A total of 159 patients were included in the study. The early mortality was 3.8%. CRP/alb was higher in these patients than in those who survived. The only independent variables for CRP/alb changes were CCI and heavy alcohol use. The CRP/alb ratio was significantly lower in non-heavy alcohol users (odds ratio [OR] 0.114, 95% confidence interval [CI] 0.024-0.541; adjusted p=0.006) than in other patients. Patients with CCI 0-1 were more likely to have a lower CRP/alb ratio than patients with CCI ≥5 (OR 0.033, 95% CI 0.004-0.284; adjusted p=0.002). Conclusions The CRP/alb ratio was high in OSCC patients with combined comorbities of age and disease history and in patients with heavy alcohol use. Oral health or tumour-related variables did not independently affect the CRP/alb ratio. The CRP/alb ratio appears suitable for prediction of OSCC patient early survival.

scholarly journals Post-traumatic stress disorder among persons with HIV who engage in heavy alcohol consumption in southwestern Uganda

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Allen Kekibiina ◽  
Julian Adong ◽  
Robin Fatch ◽  
Nneka I. Emenyonu ◽  
Kara Marson ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Traumatic Stress ◽  
Ptsd Symptoms ◽  
Post Traumatic Stress ◽  
Heavy Alcohol ◽  
Symptoms Of Depression ◽  
Heavy Alcohol Consumption ◽  
Heavy Alcohol Use ◽  
Post Traumatic ◽  
Living With Hiv

Abstract Background We aimed to describe the prevalence of PTSD symptoms and its associated factors in persons living with HIV (PLWH) in Uganda who engage in heavy alcohol use. Methods We analyzed baseline data from the Drinkers Intervention to Prevent Tuberculosis study which enrolls PLWH with latent tuberculosis who engage in heavy alcohol consumption. Using the primary care Post Traumatic Stress Disorder (PTSD) screening scale from the DSM-5 (PC-PTSD-5), probable PTSD was defined as reporting ≥3 of 5 assessed symptoms. We conducted the Alcohol Use Disorders Identification Test-Consumption and assessed demographics, smoking, symptoms of depression, and spirituality/religiosity. Results Of 421 participants enrolled from 2018 through 2020, the majority (68.2%) were male, median age was 40 years (interquartile range [IQR]: 32–47), and median AUDIT-C score was 6 [IQR: 4–8]. Half (50.1%) of the participants reported ever experiencing a traumatic event, and 20.7% reported ≥3 symptoms of PTSD. The most commonly reported PTSD symptoms in the past 1 month in the entire sample were avoidance (28.3%), nightmares (27.3%), and being constantly on guard (21.6%). In multivariable logistic regression analyses, level of alcohol use was not associated with probable PTSD (adjusted odds ratio [AOR] for each AUDIT-C point: (1.02; 95% CI: 0.92–1.14; p = 0.69); however, lifetime smoking (AOR 1.89; 95% CI: 1.10–3.24) and reporting symptoms of depression (AOR 1.89; 95% CI: 1.04–3.44) were independently associated with probable PTSD. Conclusions and recommendations A history of traumatic events and probable PTSD were frequently reported among persons who engage in heavy drinking, living with HIV in Uganda. Level of alcohol use was not associated with probable PTSD in this sample of PLWH with heavy alcohol use, however other behavioral and mental health factors were associated with probable PTSD. These data highlight the high prevalence of PTSD in this group, and the need for screening and interventions for PTSD and mental health problems.

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