scholarly journals Author Correction: MicroRNA-302a promotes neointimal formation following carotid artery injury in mice by targeting PHLPP2 thus increasing Akt signaling

2021 ◽  
Author(s):  
Ying-ying Liu ◽  
Xiu Liu ◽  
Jia-guo Zhou ◽  
Si-jia Liang
Keyword(s):  
Carotid Artery ◽  
Akt Signaling ◽  
Neointimal Formation ◽  
Carotid Artery Injury ◽  
Artery Injury

scholarly journals Peroxisome Proliferator-Activated ReceptorαPlays an Important Role in the Expression of Monocyte Chemoattractant Protein-1 and Neointimal Hyperplasia after Vascular Injury

PPAR Research ◽  
2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Yu Peng ◽  
Qiang Li ◽  
Lu Zhang ◽  
Ming Bai ◽  
Zheng Zhang
Keyword(s):  
Carotid Artery ◽  
Neointimal Hyperplasia ◽  
Peroxisome Proliferator ◽  
Neointimal Formation ◽  
Carotid Artery Injury ◽  
Monocyte Chemoattractant Protein 1 ◽  
Monocyte Chemoattractant ◽  
Monocyte Chemoattractant Protein ◽  
Artery Injury

Peroxisome proliferator-activated receptorαis a member of the nuclear receptor superfamily. It modulates smooth muscle cell proliferation and inflammatory cytokines in vitro. In this study, we tested the hypothesis that PPARαwould decrease the expression of monocyte chemoattractant protein-1 and tissue factor, and inhibit neointimal formation in a murine double carotid artery injury model. Carotid artery injury was performed in the PPARαknockout and wild type (WT) mice, treated and untreated with Wy14643, a PPARαactivator. Up-regulated MCP-1 and TF expression and more neointimal formation were observed in the PPARα−/−mice compared with WT mice. The activation of PPARαresulted in further decreased neointimal formation. Our data further suggest that the decrease in neointimal formation is due to down-regulation of MCP-1 by PPARαresulting in decreased leukocyte infiltration and TF expression.

Local delivery of green tea catechins inhibits neointimal formation in the rat carotid artery injury model

2004 ◽  
Vol 19 (5) ◽  
Author(s):  
Dong-Woon Kim ◽  
Young-Sun Park ◽  
Young-Gyu Kim ◽  
Hainan Piao ◽  
Jin-Sook Kwon ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Green Tea ◽  
Local Delivery ◽  
Neointimal Formation ◽  
Carotid Artery Injury ◽  
Tea Catechins ◽  
Artery Injury ◽  
Green Tea Catechins ◽  
Injury Model
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