Mapping of truncated O-glycans in cancers of epithelial and non-epithelial origin

2021 ◽  
Author(s):  
Troels Boldt Rømer ◽  
Mikkel Koed Møller Aasted ◽  
Sally Dabelsteen ◽  
Aaron Groen ◽  
Julia Schnabel ◽  
...  
Keyword(s):  
Epithelial Origin

Adenomatoid Tumor of the Testis, A Mesonephric Hamartoma

1971 ◽  
Vol 29 ◽  
pp. 318-319
Author(s):  
Raoul Fresco ◽  
Mary Chang-Lo
Keyword(s):  
Electron Microscopy ◽  
Epithelial Cells ◽  
Fibrous Tissue ◽  
Salient Feature ◽  
Luminal Surface ◽  
Adenomatoid Tumor ◽  
Ultrastructural Studies ◽  
Epithelial Origin ◽  
Brush Borders ◽  
Cell Processes

Confusion surrounds the nature of the “adenomatoid tumor” of the testis, as evidenced by the large number of synonyms which have been ascribed to it. Various authors have considered the tumor to be of endothelial, mesothelial or epithelial origin. There appears to be no controversy as to the stromal elements of the tumor, which consists mainly of smooth muscle and fibrous tissue. It is the irregular gland-like spaces which have given rise to the numerous theories as to its histogenesis, and even recent ultrastructural studies fail to agree on the origin of these structures.Electron microscopy of a typical intrascrotal adenomatoid tumor showed the gland-like spaces to be lined by epithelial cells (Fig. 1), rich in cytoplasmic tonofibrils and united to each other by numerous desmosomes (Fig. 2). The most salient feature of these epithelial cells was the presence on their luminal surface of numerous long and repeatedly branching microvillous structures of the type known as stereocilia (Fig. 3). These are extremely long slender cell processes which are as much as three to four times the length of those in brush borders.

First results of using of autofluorescence in diagnosis of boundaries of malignant eyelid tumors of epithelial origin

2020 ◽  
pp. 243-247
Author(s):  
A.N. Bochkareva ◽  
◽  
V.V. Egorov ◽  
G.P. Smoliakova ◽  
P.A. Banshchikov ◽  
...  
Keyword(s):  
Eyelid Tumors ◽  
Epithelial Origin ◽  
First Results

The epithelial origin of lymphocytes in the palatine tonsil of rabbits

1970 ◽  
Vol 2 (1) ◽  
pp. 33-45 ◽  
Author(s):  
Bettina H. Harrison ◽  
Conald I. Patt ◽  
John T. Albright
Keyword(s):  
Palatine Tonsil ◽  
Epithelial Origin

Survay on the infiltration of NK cell in various types of cutaneous tumors of epithelial origin

1990 ◽  
Vol 1 (2) ◽  
pp. 137 ◽  
Author(s):  
Y. Miyagoe ◽  
J. Nakayama ◽  
D. Xu ◽  
T. Miyaoka ◽  
Y. Hori
Keyword(s):  
Nk Cell ◽  
Epithelial Origin

scholarly journals Mural ameloblastoma- A case report

2021 ◽  
Vol 7 (4) ◽  
pp. 302-305
Author(s):  
Sruthi Chandra V ◽  
V Ramesh ◽  
P D Balamurali ◽  
Nirima Oza
Keyword(s):  
Case Report ◽  
Benign Neoplasm ◽  
Risk Of Recurrence ◽  
Epithelial Origin

Ameloblastoma is a benign neoplasm of odontogenic epithelial origin which comprises of several clinical, radiological and histological varieties. Among these, unicystic variant is the least explored and its mural subtype shows a high aggressiveness and risk of recurrence and comparable with that of conventional ameloblastoma. Herein, we present a case of mural ameloblastoma of maxilla in a 32-year old female.

scholarly journals Tc-99m direct radiolabeling of monoclonal antibody ior egf/r3: quality control and image studies in mice

2005 ◽  
Vol 48 (spe2) ◽  
pp. 29-35 ◽  
Author(s):  
Carla Roberta Dias ◽  
Barbara Marczewski ◽  
Vanessa Moraes ◽  
Marycel Figols de Barboza ◽  
João Alberto Osso Junior
Keyword(s):  
Monoclonal Antibody ◽  
Nuclear Medicine ◽  
Growth Factor Receptor ◽  
Lyophilized Formulation ◽  
Epithelial Origin ◽  
Epidermal Growth ◽  
High Yields ◽  
Efficiency Effects

Monoclonal antibodies (Mabs) have been useful for immunoscintigraphic applications in clinical diagnosis since they were introduced in the practice of nuclear medicine. The ior egf/r3 (Centis, Cuba) is a murine monoclonal antibody against epidermal growth factor receptor (EGF-R) and has been widely used in the radioimmunodiagnosis of tumors of epithelial origin. Labeled with 99mTc, its main application in Nuclear Medicine is the follow up, detection and evaluation of tumor recurrences. The objective of this work is to describe the preparation of a lyophilized formulation (kit) for radiolabeling the Mab ior egf/r3 with 99mTc for immunoscintigraphic applications. Radiolabeling efficiency, effects on immunoreactivity, image studies and stability of the formulation are reported. The study demonstrated that the kit formulation can be labeled with 99mTc at high yields and can be used to visualize in vivo human tumors of epithelial origin by immunoscintigraphy studies.

scholarly journals 2114

2017 ◽  
Vol 1 (S1) ◽  
pp. 57-57
Author(s):  
Jennifer Knudtson ◽  
Ya-Guang Liu ◽  
Marlen Tellez Santos ◽  
Rajeshwar Tekmal ◽  
Ratna Vadlamudi ◽  
...  
Keyword(s):  
Positive Staining ◽  
Test Results ◽  
Endometriotic Lesion ◽  
Vitro Assay ◽  
Epithelial Origin ◽  
Immortalized Cells ◽  
Study Population ◽  
Chromosomal Profile

OBJECTIVES/SPECIFIC AIMS: To further elucidate the role of estrogen receptor β (ER-β) in the early endometriotic lesion attachment. METHODS/STUDY POPULATION: EECs were immortalized using a telomerase vector. Immortalized cells and parental cells were characterized by genotyping, and expression of ER-β as well as other epithelial cell markers. ER-β was knocked-down in immortalized EECs using lentivirus-mediated shRNA transduction. ER-β knockdown was confirmed by RT-qPCR and Western analysis. EEC cells with or without ER-β knockdown were used to assess their attachment to PMCs in an established in vitro assay (Lucidi, 2005). Results were analyzed with Student t-test. RESULTS/ANTICIPATED RESULTS: Genotyping using karyotype assay confirmed a normal chromosomal profile. Also positive staining for cytokeratin and lack of any staining with vimentin confirms the epithelial origin of these cells. ER-β knockdown has a significant decrease in attachment compared to control (p=0.02). DISCUSSION/SIGNIFICANCE OF IMPACT: Primary and immortalized cells were 46XX, cytokeratin positive, and vimentin negative confirming their epithelial origin. ER-β knockdown has a significant decrease in attachment compared with control.

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