scholarly journals Reflections on dynamic consent in biomedical research: the story so far

Author(s):  
Harriet J. A. Teare ◽  
Megan Prictor ◽  
Jane Kaye

AbstractDynamic consent (DC) was originally developed in response to challenges to the informed consent process presented by participants agreeing to ‘future research’ in biobanking. In the past 12 years, it has been trialled in a number of different projects, and examined as a new approach for consent and to support patient engagement over time. There have been significant societal shifts during this time, namely in our reliance on digital tools and the use of social media, as well as a greater appreciation of the integral role of patients in biomedical research. This paper reflects on the development of DC to understand its importance in an age where digital health is becoming the norm and patients require greater oversight and control of how their data may be used in a range of settings. As well as looking back, it looks forwards to consider how DC could be further utilised to enhance the patient experience and address some of the inequalities caused by the digital divide in society.

2020 ◽  
pp. 193229682097640
Author(s):  
Michelle Dugas ◽  
Weiguang Wang ◽  
Kenyon Crowley ◽  
Anand K. Iyer ◽  
Malinda Peeples ◽  
...  

Background: Digital health solutions targeting diabetes self-care are popular and promising, but important questions remain about how these tools can most effectively help patients. Consistent with evidence of the salutary effects of note-taking in education, features that enable annotation of structured data entry might enhance the meaningfulness of the interaction, thereby promoting persistent use and benefits of a digital health solution. Method: To examine the potential benefits of note-taking, we explored how patients with type 2 diabetes used annotation features of a digital health solution and assessed the relationship between annotation and persistence in engagement as well as improvements in glycated hemoglobin (A1C). Secondary data from 3142 users of the BlueStar digital health solution collected between December 2013 and June 2017 were analyzed, with a subgroup of 372 reporting A1C lab values. Results: About a third of patients recorded annotations while using the platform. Annotation themes largely reflected self-management behaviors (diet, physical activity, medication adherence) and well-being (mood, health status). Early use of contextual annotations was associated with greater engagement over time and with greater improvements in A1C. Conclusions: Our research provides preliminary evidence of the benefits of annotation features in a digital health solution. Future research is needed to assess the causal impact of note-taking and the moderating role of thematic content reflected in notes.


2021 ◽  
Author(s):  
Keng Yang ◽  
Yekang Hu ◽  
Hanying Qi

BACKGROUND Digital health is growing at a rapid pace, and digital health literacy has tremendous potential to promote health outcomes, bridge the digital divide, and improve health inequalities. OBJECTIVE The purposes of this study are to conduct a systematic bibliometric analysis on the field of dig-ital health literacy and to understand the research context and trends in this field. METHODS A total of 1,955 scientific publications were collected from the Web of Science (WoS) core col-lection. Institutional cooperation, journal co-citation, theme bursting, keyword co-occurrence, author cooperation, author co-citation, literature co-citation and references in the field of digi-tal health literacy were analyzed using the VOSviewer and CiteSpace knowledge mapping tools. RESULTS The results demonstrated that the United States was the leader in number of publications and citations in this field. The University of California System was first in terms of institutional contributions. The Journal of Medical Internet Research led in number of publications, cita-tions and co-citations. Research areas in the field of digital health literacy mainly include the definition and scale of health literacy, health literacy and health outcomes, health literacy and the digital divide, and the influencing factors of health literacy. CONCLUSIONS We summarize research progress in the field of digital health literacy and reveal the context, trends, and trending topics of digital health literacy research through statistical analysis and network visualization. Our work can serve as a fundamental reference and directional guide for future research in this field.


2019 ◽  
Vol 72 (3) ◽  
pp. 473-504 ◽  
Author(s):  
William M Foster ◽  
John S Hassard ◽  
Jonathan Morris ◽  
Julie Wolfram Cox

This article analyses contemporary issues relevant to understanding the changing nature of management and managerial work. The argument is developed in four parts. First, to provide context, we offer an overview of the literature on the organization and control of managerial work, tracing contributions mainly from the early 1950s onwards. Second, we discuss the first of two related concerns relevant to understanding the contemporary nature of managerial work – strategies of organizational restructuring: an analysis highlighting the role of downsizing and delayering within corporate campaigns promoting ‘post-bureaucratic’ systems. Third, we extend this discussion by addressing how such corporate restructuring affects managers in their everyday work – notably in relation to the perceptions and realities of growing job insecurity and career uncertainty: an analysis that frequently draws upon our own investigations to establish an agenda for future research. The article concludes by summarizing the content of four research articles whose arguments relate to issues discussed in this analysis of managerial work.


1976 ◽  
Vol 62 (6) ◽  
pp. 609-614 ◽  
Author(s):  
Giulio Tarro ◽  
Giovan Giacomo Giordano ◽  
Armando Tripodi ◽  
Romolo Cerra ◽  
Mario Di Gioia ◽  
...  

The finding of a nuclear antigen by anticomplement immunofluorescence in cells treated with cytosine-arabinoside after infection of Herpes Simplex Virus (HSV), opens a new approach to the problem of the role of this virus in certain human cancers. Complement-fixing tests of HSV markers with cancer and control human sera as well as with hyperimmune guinea pig antisera are discussed, suggesting another parameter for studies of squamous cell carcinomas. The finding of HSV antigens in selected tumors as the expression of repressed viral genome proves a continuing release of virus specific message and supports the important role of the virus in the development of the tumor.


1983 ◽  
Vol 4 (2) ◽  
pp. 405-424 ◽  
Author(s):  
IRENE F. GOODMAN

The purpose of this article is to argue that exploring the role of television in family life is not solely a matter of studying its effects on family members; it also involves looking at TV as a phenomenon that serves a whole range of social purposes the study of which can shed light on general family functioning. In this review, existing theoretical models and research are discussed in order to show why a new model—family systems—is being proposed. The application of the family systems model to the arena of television use in the family is one that has not been previously explored. Emphasis will be placed on two family systems principles that are important in the study of the family's use of and interaction around television. Current measurement techniques will be examined to illustrate that a new approach, reflecting interaction and process, is needed. Components of a family systems model—structure, development, and adaptation—are adapted in order to discuss TV's function in the family. Suggestions for future research and implications for therapy are offered.


Author(s):  
Tannis Y. Arbuckle ◽  
Dolores Pushkar ◽  
June Chaikelson ◽  
David Andres

ABSTRACTThis paper reviews the literature on the relation of coping and control processes to health outcomes in late adulthood and presents new data on relations between coping and control processes and health for 295 World War II veterans. The results for the veterans showed that health was positively associated with cognitive coping, and negatively associated with behavioural coping and avoidance. No association was found between perceived locus of control and health. These findings, together with those in the literature, were discussed in terms of their implications for future research on the role of coping and control in health maintenance and their significance for people working with older persons.


Author(s):  
Amrut.S. Salunke ◽  
Adarsh Ramkalap Sharma ◽  
Sonali Sunil Tadasarkar

Corona virus disease is caused by severe acute respiratory syndrome Corona virus 2[SARS-CoV-2] infections attacking multisystem of the human body at a time, of which respiratory system, immune system and circulatory system are most affected. The complications of the disease arise or it becomes more pronounced, after the cytokinine storm phase becomes established leading to hypercoagulative state affecting the circulatory and respiratory system. In Ayurveda, there is a holistic approach in treating the disease and the body as a whole. Drugs such as Haridra, Tulasi, Guduchi, Yashtimadhu, Twak, Triphala, Lavang, Maricha, Pippali etc and few Visha Dravyas like Langali, Dravanti etc can be used a single drug or a group of drugs with their phytochemical properties and active principles leading to delay and prevention of hyper coagulable states thereby preventing the cascade of complications caused by COVID, additionally having anti-inflammatory and immune-modulatory effect. Scientific research on these drugs may reveal a new approach for management and prevention of COVID related complications and can be a subject of future research interest.


2020 ◽  
pp. 026666692091389 ◽  
Author(s):  
Najeeb Gambo Abdulhamid ◽  
Daniel Azerikatoa Ayoung ◽  
Armin Kashefi ◽  
Boyce Sigweni

This study reviews literature on the use of Social Media (SM) in emergency response operations while identifying gaps in this research stream that need attention from Information Systems (IS) researchers. The research is grounded in past works and attempts to build on research on the application of SM in emergencies. It focuses on understanding the role of SM in the prevention, management and response to emergencies. The review contains a detailed literature exposition of IS and disasters journals. The appraisal of such research stream led the review to focus on the concept of digital volunteerism as an offshoot of crowdsourcing initiatives. Findings from the review reveal that previous studies overlooked the interfacing challenges between formal and traditional aid agencies on one hand and digital humanitarians on the other. Consequently, we identify gaps in the extant literature and propose areas of interest for future research.


2016 ◽  
Vol 28 (5) ◽  
pp. 774-785 ◽  
Author(s):  
Vesna Spasojevic Brkic ◽  
Branislav Tomic

Purpose – Lean management and Six Sigma concepts are derived from two different points of view, but it is evident that the role of employees is crucial in both concepts. The purpose of this paper is to survey which employees’ behaviour dimensions can lead organization to better concepts integration and how Lean Six Sigma activity contributes to employees’ performance. Design/methodology/approach – Research methodology is designed to empirically check, on large sample of companies in multinational company supply chain, if employees’ factors are both predictor and response variables of Lean Six Sigma concept. To check stated hypothesis factor, reliability and multiple regression analysis are used. Findings – The first finding of this study is that reward system and training are significant predictors of Lean Six Sigma activities. The second part of findings shows that Lean Six Sigma dimensions, such as Define, Measure, Analyze, Improve, and Control/Define, Measure, Analyze, Design, and Validate, 5S and Kanban positively influences employees’ performance, described by employee satisfaction, absenteeism, salaries and benefits, employees’ commitment and employee turnover rate. Research limitations/implications – Poka-Yoke application is not found as a significant predictor of employees’ performance. Accordingly, to explore that interesting finding, possible future research topic is more detailed analysis of Poka-Yoke application in similar supply chains. A longitudinal analysis using structural equation is possible direction of future work, too. Practical implications – This survey answers the need for Lean and Six Sigma unified methodology achievement in soft factors area and gives applicable results for companies in supply chain that produces low-volume, high-complexity products. Originality/value – Original and valuable conclusion is that employees’ factors are both predictor and response variables of Lean Six Sigma concept application.


2015 ◽  
Vol 21 (7) ◽  
pp. 845-853 ◽  
Author(s):  
Xianhai Meng

The importance of inter-organizational trust to project success has been increasingly highlighted in the construction industry. This study aims to explore the role of trust between project parties. It adopts a combination of quantitative and qualitative methodologies. Based on the analysis of the responses of a questionnaire survey, trust is demonstrated to have a significant contribution to the development of cooperative or collaborative relationships; fostering trust proves to have a major influence on the improvement of project performance; and some relationship and performance indicators are found to have closer associations with trust than others so that trust is more important to the development of relationship and the improvement of performance in these aspects. The analysis of questionnaire responses also provides significant evidence for the reduction in monitoring and control following the increase of mutual trust. The questionnaire survey is followed by a series of expert interviews, both of which contribute to the establishment of a model that links trust with relationship and performance and distinguishes the new approach that is based on trust from the traditional mechanism that relies on monitoring and control.


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