Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells

Oncogene ◽

10.1038/sj.onc.1207351 ◽

2003 ◽

Vol 23 (14) ◽

pp. 2554-2558 ◽

Author(s):

Qin He ◽

Ying Huang ◽

M Saeed Sheikh

Keyword(s):

Proteasome Inhibitor ◽

Death Receptor ◽

Death Receptor 5 ◽

Proteasome Inhibitor Mg132

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432: Proteasome Inhibitor MG132 Induces Death Receptor 5 (DR5) Through CCAAT/Enhancer-Binding Protein Homologous Protein (CHOP) and Enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL/AP02L)-Induced Apoptosis in DU145, Human Hormone-Independent Prostate Cancer Cells

The Journal of Urology ◽

10.1016/s0022-5347(18)32688-0 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 140-140

Author(s):

Takumi Shiraishi ◽

Tatsushi Yoshida ◽

Yoichi Mizutani ◽

Takashi Yasuda ◽

Terukazu Nakamura ◽

...

Keyword(s):

Proteasome Inhibitor ◽

Tumor Necrosis ◽

Death Receptor ◽

Death Receptor 5 ◽

Proteasome Inhibitor Mg132 ◽

Prostate Cancer Cells ◽

Homologous Protein ◽

Enhancer Binding Protein ◽

Induced Apoptosis ◽

Necrosis Factor

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Proteasome Inhibitor MG132 Induces Death Receptor 5 through CCAAT/Enhancer-Binding Protein Homologous Protein

Cancer Research ◽

10.1158/0008-5472.can-05-0693 ◽

2005 ◽

Vol 65 (13) ◽

pp. 5662-5667 ◽

Author(s):

Tatsushi Yoshida ◽

Takumi Shiraishi ◽

Susumu Nakata ◽

Mano Horinaka ◽

Miki Wakada ◽

...

Keyword(s):

Proteasome Inhibitor ◽

Binding Protein ◽

Death Receptor ◽

Death Receptor 5 ◽

Proteasome Inhibitor Mg132 ◽

Homologous Protein ◽

Enhancer Binding Protein ◽

Ccaat Enhancer Binding Protein

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The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5

10.18632/oncotarget.3947 ◽

2015 ◽

Vol 6 (19) ◽

pp. 17532-17542 ◽

Author(s):

Bo Han ◽

Weilong Yao ◽

You-Take Oh ◽

Jing-Shan Tong ◽

Shaohua Li ◽

...

Keyword(s):

Proteasome Inhibitor ◽

Death Receptor ◽

Death Receptor 5 ◽

The Novel ◽

Extrinsic Apoptosis

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A Novel Fully Human Agonistic Single Chain Fragment Variable Antibody Targeting Death Receptor 5 with Potent Antitumor Activity In Vitro and In Vivo

International Journal of Molecular Sciences ◽

10.3390/ijms18102064 ◽

2017 ◽

Vol 18 (10) ◽

pp. 2064 ◽

Author(s):

Gaoxin Lei ◽

Menglong Xu ◽

Zhipan Xu ◽

Lili Gu ◽

Chenchen Lu ◽

...

Keyword(s):

Antitumor Activity ◽

Death Receptor ◽

Death Receptor 5 ◽

Single Chain ◽

Chain Fragment ◽

Single Chain Fragment Variable ◽

Antibody Targeting ◽

Single Chain Fragment

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Quercetin enhances apoptotic effect of tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer‐binding protein homologous protein (CHOP)‐death receptor 5 pathway

Cancer Science ◽

10.1111/cas.12395 ◽

2014 ◽

Vol 105 (5) ◽

pp. 520-527 ◽

Author(s):

Liu Yi ◽

Yang Zongyuan ◽

Gong Cheng ◽

Zhang Lingyun ◽

Yu GuiLian ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Tumor Necrosis ◽

Death Receptor ◽

Ovarian Cancer Cells ◽

Oxygen Species ◽

Death Receptor 5 ◽

Homologous Protein ◽

Enhancer Binding Protein ◽

Apoptotic Effect ◽

Necrosis Factor

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Endoplasmic reticulum calcium pool depletion-induced apoptosis is coupled with activation of the death receptor 5 pathway

Oncogene ◽

10.1038/sj.onc.1205345 ◽

2002 ◽

Vol 21 (17) ◽

pp. 2623-2633 ◽

Author(s):

Qin He ◽

Dong Ik Lee ◽

Rong Rong ◽

Myounghee Yu ◽

Xiuquan Luo ◽

...

Keyword(s):

Endoplasmic Reticulum ◽

Death Receptor ◽

Death Receptor 5 ◽

Endoplasmic Reticulum Calcium ◽

Induced Apoptosis ◽

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Structural basis of LaDR5, a novel agonistic anti-death receptor 5 (DR5) monoclonal antibody, to inhibit DR5/TRAIL complex formation

BMC Immunology ◽

10.1186/1471-2172-13-40 ◽

2012 ◽

Vol 13 (1) ◽

pp. 40

Author(s):

Chunxia Qiao ◽

Meiyun Hu ◽

Leiming Guo ◽

Ming Lv ◽

Zhou Lin ◽

...

Keyword(s):

Monoclonal Antibody ◽

Complex Formation ◽

Death Receptor ◽

Structural Basis ◽

Death Receptor 5

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Dyclonine and alverine citrate enhance the cytotoxic effects of proteasome inhibitor MG132 on breast cancer cells

International Journal of Molecular Medicine ◽

10.3892/ijmm_00000118 ◽

1998 ◽

Author(s):

Xie

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Proteasome Inhibitor ◽

Breast Cancer Cells ◽

Proteasome Inhibitor Mg132 ◽

Cytotoxic Effects

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Ionizing radiation enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulations of death receptor 4 (DR4) and death receptor 5 (DR5) in human osteosarcoma cells

Journal of Orthopaedic Research® ◽

10.1002/jor.21056 ◽

2009 ◽

Vol 28 (6) ◽

pp. 739-745 ◽

Author(s):

Takeshi Hori ◽

Takashi Kondo ◽

Masahiko Kanamori ◽

Yoshiaki Tabuchi ◽

Ryohei Ogawa ◽

...

Keyword(s):

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Death Receptor ◽

Death Receptor 5 ◽

Osteosarcoma Cells ◽

Human Osteosarcoma ◽

Human Osteosarcoma Cells ◽

Induced Apoptosis ◽

Death Receptor 4 ◽

Necrosis Factor

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CSC ‐3436 sensitizes triple negative breast cancer cells to TRAIL ‐induced apoptosis through ROS ‐mediated p38/ CHOP /death receptor 5 signaling pathways

Environmental Toxicology ◽

10.1002/tox.23372 ◽

2021 ◽

Author(s):

Chun‐Chen Huang ◽

Yi‐Ching Cheng ◽

Ying‐Chao Lin ◽

Chun‐Hung Chou ◽

Chi‐Tang Ho ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Cells ◽

Signaling Pathways ◽

Triple Negative Breast Cancer ◽

Breast Cancer Cells ◽

Triple Negative ◽

Death Receptor ◽

Death Receptor 5 ◽

Induced Apoptosis

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