scholarly journals Biofilm formation of the black yeast-like fungus Exophiala dermatitidis and its susceptibility to antiinfective agents

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Lisa Kirchhoff ◽  
Maike Olsowski ◽  
Katrin Zilmans ◽  
Silke Dittmer ◽  
Gerhard Haase ◽  
...  
2017 ◽  
Vol 183 (1) ◽  
pp. 201-212 ◽  
Author(s):  
Monika Novak Babič ◽  
Jerneja Zupančič ◽  
Nina Gunde-Cimerman ◽  
Sybren de Hoog ◽  
Polona Zalar

2020 ◽  
Vol 8 (2) ◽  
pp. 67-69
Author(s):  
Dilia Martinez-Mendez ◽  
Maria Andrea Castillo ◽  
Primavera Alvarado ◽  
Alexis Fernandez ◽  
Kendy Eduardo Urdaneta ◽  
...  

2008 ◽  
Vol 61 ◽  
pp. 145-155 ◽  
Author(s):  
M. Sudhadham ◽  
S. Prakitsin ◽  
S. Sivichai ◽  
R. Chaiyarat ◽  
G.M Dorrestein ◽  
...  

Cells ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 963 ◽  
Author(s):  
Teja Lavrin ◽  
Tilen Konte ◽  
Rok Kostanjšek ◽  
Simona Sitar ◽  
Kristina Sepčič ◽  
...  

The neurotropic and extremophilic black yeast Exophiala dermatitidis (Herpotrichellaceae) inhabits diverse indoor environments, in particular bathrooms, steam baths, and dishwashers. Here, we show that the selected strain, EXF-10123, is polymorphic, can grow at 37 °C, is able to assimilate aromatic hydrocarbons (toluene, mineral oil, n-hexadecane), and shows abundant growth with selected neurotransmitters (acetylcholine, gamma-aminobutyric acid, glycine, glutamate, and dopamine) as sole carbon sources. We have for the first time demonstrated the effect of E. dermatitidis on neuroblastoma cell model SH-SY5Y. Aqueous and organic extracts of E. dermatitidis biomass reduced SH-SY5Y viability by 51% and 37%, respectively. Melanized extracellular vesicles (EVs) prepared from this strain reduced viability of the SH-SY5Y to 21%, while non-melanized EVs were considerably less neurotoxic (79% viability). We also demonstrated direct interactions of E. dermatitidis with SH-SY5Y by scanning electron and confocal fluorescence microscopy. The observed invasion and penetration of neuroblastoma cells by E. dermatitidis hyphae presumably causes the degradation of most neuroblastoma cells in only three days. This may represent a so far unknown indirect or direct cause for the development of some neurodegenerative diseases such as Alzheimer’s.


2015 ◽  
Vol 128 ◽  
pp. 39-57 ◽  
Author(s):  
Donatella Tesei ◽  
Gorji Marzban ◽  
Martina Marchetti-Deschmann ◽  
Hakim Tafer ◽  
Elsa Arcalis ◽  
...  

PLoS ONE ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e0148166 ◽  
Author(s):  
Jerneja Zupančič ◽  
Monika Novak Babič ◽  
Polona Zalar ◽  
Nina Gunde-Cimerman

2010 ◽  
Vol 80 (2) ◽  
pp. 138-142 ◽  
Author(s):  
M. Sudhadham ◽  
G.S. de Hoog ◽  
S.B.J. Menken ◽  
A.H.G. Gerrits van den Ende ◽  
P. Sihanonth

Data in Brief ◽  
2015 ◽  
Vol 5 ◽  
pp. 372-375 ◽  
Author(s):  
Donatella Tesei ◽  
Gorji Marzban ◽  
Martina Marchetti-Deschmann ◽  
Hakim Tafer ◽  
Elsa Arcalis ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document