scholarly journals Continuous flow chemistry: a discovery tool for new chemical reactivity patterns

2014 ◽  
Vol 12 (22) ◽  
pp. 3611-3615 ◽  
Author(s):  
Jan Hartwig ◽  
Jan B. Metternich ◽  
Nikzad Nikbin ◽  
Andreas Kirschning ◽  
Steven V. Ley
Keyword(s):  
Continuous Flow ◽  
Chemical Reactivity ◽  
Flow Chemistry ◽  
Reactivity Pattern ◽  
Batch Mode ◽  
Continuous Flow Chemistry

A new reactivity pattern and extended reaction scope has been obtained by transferring a reaction from batch mode to flow.

ChemInform Abstract: Continuous Flow Chemistry: A Discovery Tool for New Chemical Reactivity Patterns.

ChemInform ◽  
2014 ◽  
Vol 45 (44) ◽  
pp. no-no
Author(s):  
Jan Hartwig ◽  
Jan B. Metternich ◽  
Nikzad Nikbin ◽  
Andreas Kirschning ◽  
Steven V. Ley
Keyword(s):  
Continuous Flow ◽  
Chemical Reactivity ◽  
Flow Chemistry ◽  
Continuous Flow Chemistry

scholarly journals A practical experiment to teach students continuous flow and physico-chemical methods: acetylation of ethylene diamine in liquid bi-phase

2020 ◽  
Author(s):  
Mary Bayana ◽  
A. John Blacker ◽  
Adam D. Clayton ◽  
Katherine E. Jolley ◽  
Ricardo Labes ◽  
...  
Keyword(s):  
Continuous Flow ◽  
Flow Chemistry ◽  
Batch Mode ◽  
Flow Reactors ◽  
Multiple Parameters ◽  
Continuous Flow Chemistry ◽  
Physico Chemical ◽  
Different Types ◽  
Synthetic Reactions ◽  
Continuous Flow Reactors

Abstract Despite growing applications being reported both in academia and industry, continuous flow chemistry remains a relatively untaught field across most chemistry undergraduate courses. This is particularly true in laboratory practical classes, where it is often deemed simpler to carry out synthetic reactions in traditional batch mode using round-bottomed flasks. Herein, we report the development of an undergraduate project that utilises cheap and readily available materials to construct continuous flow reactors. The students compare the performance of different types of reactors and conditions in a biphasic selective acetylation of a symmetrical diamine. Throughout the investigation, the students can vary multiple parameters as they optimise the reaction, thus actively learning and readjusting them based on their improved understanding. The experiments give the students an appreciation of continuous flow techniques in comparison to batch.

scholarly journals Application of Reactor Engineering Concepts in Continuous Flow Chemistry: A Review

2021 ◽  
Author(s):  
Nicole Candice Neyt ◽  
Darren Lyall Riley
Keyword(s):  
Rapid Growth ◽  
Continuous Flow ◽  
Flow Chemistry ◽  
The Past ◽  
Continuous Flow Chemistry

The adoption of flow technology for the manufacture of chemical entities, and in particular pharmaceuticals, has seen rapid growth over the past two decades with the technology now blurring the...

scholarly journals Continuous-flow chemistry in chemical education

2017 ◽  
Vol 7 (3–4) ◽  
pp. 157-158 ◽  
Author(s):  
Daniel Blanco-Ania ◽  
Floris P. J. T. Rutjes
Keyword(s):  
Continuous Flow ◽  
Chemical Education ◽  
Flow Chemistry ◽  
Continuous Flow Chemistry

Towards 4th industrial revolution efficient and sustainable continuous flow manufacturing of active pharmaceutical ingredients

2022 ◽  
Author(s):  
Cloudius Sagandira ◽  
Sinazo Nqeketo ◽  
Kanysile Mhlana ◽  
Thembela Sonti ◽  
Paul Watts ◽  
...  
Keyword(s):  
Pharmaceutical Industry ◽  
Continuous Flow ◽  
Industrial Revolution ◽  
Flow Chemistry ◽  
Active Pharmaceutical Ingredients ◽  
New Paradigm ◽  
Pharmaceutical Ingredients ◽  
Continuous Flow Chemistry

Continuous flow chemistry has opened a new paradigm in both the laboratory and pharmaceutical industry. This review details the recently reported literature on continuous multistep telescoped synthesis of active pharmaceutical...

scholarly journals Scalable Synthesis of Norbornadienes via in situ Cracking of Dicyclopentadiene Using Continuous Flow Chemistry

2021 ◽  
Author(s):  
Jessica Orrego‐Hernández ◽  
Helen Hölzel ◽  
Maria Quant ◽  
Zhihang Wang ◽  
Kasper Moth‐Poulsen
Keyword(s):  
Continuous Flow ◽  
Flow Chemistry ◽  
Continuous Flow Chemistry ◽  
Scalable Synthesis

4 Practical aspects of performing continuous flow chemistry

2021 ◽  
pp. 145-178
Author(s):  
Kian Donnelly ◽  
Mara Di Filippo ◽  
Cormac Bracken ◽  
Marcus Baumann
Keyword(s):  
Continuous Flow ◽  
Flow Chemistry ◽  
Continuous Flow Chemistry

scholarly journals Catalytic Methods in Flow Chemistry

Catalysts ◽  
2019 ◽  
Vol 9 (8) ◽  
pp. 663
Author(s):  
Christophe Len ◽  
Renzo Luisi
Keyword(s):  
Chemical Synthesis ◽  
Continuous Flow ◽  
Flow Chemistry ◽  
Pharmaceutical Companies ◽  
Enabling Technology ◽  
Continuous Flow Chemistry ◽  
The Way

Continuous flow chemistry is radically changing the way of performing chemical synthesis, and several chemical and pharmaceutical companies are now investing in this enabling technology [...]

A Vilsmeier Chloroformylation by Continuous Flow Chemistry

2020 ◽  
Vol 24 (10) ◽  
pp. 2260-2265
Author(s):  
Manuel Carrera ◽  
Laurens De Coen ◽  
Michelle Coppens ◽  
Wim Dermaut ◽  
Christian V. Stevens
Keyword(s):  
Continuous Flow ◽  
Flow Chemistry ◽  
Continuous Flow Chemistry
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