scholarly journals Binding of amphiphilic and triphilic block copolymers to lipid model membranes: the role of perfluorinated moieties

Soft Matter ◽  
2014 ◽  
Vol 10 (33) ◽  
pp. 6147-6160 ◽  
Author(s):  
Christian Schwieger ◽  
Anja Achilles ◽  
Sven Scholz ◽  
Jan Rüger ◽  
Kirsten Bacia ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Lipid Membranes ◽  
Model Membranes ◽  
Amphiphilic Block Copolymers ◽  
End Caps

Attachment of fluorophilic end caps to amphiphilic block copolymers increases their interaction with lipid membranes and enables the polymer's translocation.

An isotopic effect in self-assembly of amphiphilic block copolymers: the role of hydrogen bonds

Soft Matter ◽  
2009 ◽  
Vol 5 (24) ◽  
pp. 5003 ◽  
Author(s):  
Rina Shvartzman-Cohen ◽  
Chun-lai Ren ◽  
Igal Szleifer ◽  
Rachel Yerushalmi-Rozen
Keyword(s):  
Block Copolymers ◽  
Hydrogen Bonds ◽  
Self Assembly ◽  
Isotopic Effect ◽  
Amphiphilic Block Copolymers

Amphiphilic block copolymers as efficiency boosters in microemulsions: a SANS investigation of the role of polymers

2002 ◽  
Vol 74 (0) ◽  
pp. s392-s395 ◽  
Author(s):  
H. Endo ◽  
J. Allgaier ◽  
M. Mihailescu ◽  
M. Monkenbusch ◽  
G. Gompper ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Amphiphilic Block Copolymers

Interaction of poloxamine block copolymers with lipid membranes: Role of copolymer structure and membrane cholesterol content

2015 ◽  
Vol 133 ◽  
pp. 270-277 ◽  
Author(s):  
Isabel Sandez-Macho ◽  
Matilde Casas ◽  
Emilio V. Lage ◽  
M. Isabel Rial-Hermida ◽  
Angel Concheiro ◽  
...  
Keyword(s):  
Block Copolymers ◽  
Lipid Membranes ◽  
Cholesterol Content ◽  
Membrane Cholesterol ◽  
Copolymer Structure

Role of Hydrophobic and Hydrophilic Interactions of Organotin and Organolead Compounds with Model Lipid Membranes

1997 ◽  
Vol 52 (3-4) ◽  
pp. 209-216 ◽  
Author(s):  
Janina Gabrielska ◽  
Janusz Sarapuk ◽  
Stanisław Przestalski
Keyword(s):  
Lipid Bilayer ◽  
Organic Compounds ◽  
Lipid Membranes ◽  
Model Membranes ◽  
Model Lipid Membranes ◽  
Cationic Detergents ◽  
Mechanism Of Interaction ◽  
Organolead Compounds ◽  
Planar Membranes

AbstractThe present study was conducted to clarify the mechanism of toxicity of organic compounds using lipid model membranes (liposomes and planar lipid membranes).The compounds studied were trialkyltin and trialkyllead chlorides, dialkyltin dichlorides and some inorganic forms of those metals. Two different (anionic and cationic) detergents were also used in the experiments to change the surface properties of liposomes. As a measure of interaction between the compounds studied and model membranes were the release of liposome bound praseodymium and the change in stability of planar membranes under the influence of those compounds.On the basis of the results obtained it was postulated that the mechanism of interaction between tin-and leadorganics and model lipid membranes is a combination of different factors featuring interacting sides. The most important properties determining the behaviour of organic compounds in the interaction were lipophilicity and polarity of different parts of the organics and the steric arrangement they can take in the medium. On the other hand, the surface potential of the lipid bilayer and the environment of the lipid molecules, that play a significant role in the availability of the lipid bilayer to the organics, were important factors in the interaction.

scholarly journals Polymerisation-induced self-assembly (PISA) as a straightforward formulation strategy for stimuli-responsive drug delivery systems and biomaterials: recent advances

2021 ◽  
Vol 9 (1) ◽  
pp. 38-50
Author(s):  
Hien Phan ◽  
Vincenzo Taresco ◽  
Jacques Penelle ◽  
Benoit Couturaud
Keyword(s):  
Drug Delivery ◽  
Block Copolymers ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Delivery Systems ◽  
Amphiphilic Block Copolymers ◽  
Stimuli Responsive ◽  
Site Specific ◽  
On Demand ◽  
Redox Agents

Stimuli-responsive amphiphilic block copolymers obtained by PISA have emerged as promising nanocarriers for enhancing site-specific and on-demand drug release in response to a range of stimuli such as pH, redox agents, light or temperature.

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