An intracellular protein delivery platform based on glutathione-responsive protein nanocapsules

2016 ◽  
Vol 52 (93) ◽  
pp. 13608-13611 ◽  
Author(s):  
Jie Li ◽  
Linlin Zhang ◽  
Yang Liu ◽  
Jing Wen ◽  
Di Wu ◽  
...  
Keyword(s):  
Protein Delivery ◽  
Intracellular Delivery ◽  
Intracellular Protein ◽  
Disulfide Crosslinking ◽  
Efficient Strategy ◽  
Protein Polymer ◽  
Delivery Platform ◽  
The Stability ◽  
Intracellular Protein Delivery ◽  
Polymer Assembly

We reported an efficient strategy for the intracellular delivery of proteins based on assembling proteins with a self-crosslinkable polymer. The disulfide-crosslinking structure enhances the stability of the protein–polymer assembly, and also allows effective dissociation of the assembly in response to glutathione.

A versatile pH-responsive platform for intracellular protein delivery using calcium phosphate nanoparticles

2015 ◽  
Vol 3 (47) ◽  
pp. 9115-9121 ◽  
Author(s):  
Bingru Zeng ◽  
Hongdong Shi ◽  
Yangzhong Liu
Keyword(s):  
Calcium Phosphate ◽  
Protein Delivery ◽  
Intracellular Delivery ◽  
Endosomal Escape ◽  
Ph Responsive ◽  
Intracellular Protein ◽  
Calcium Phosphate Nanoparticles ◽  
Intracellular Protein Delivery

A highly biocompatible nanoplatform for the intracellular delivery of different proteins, exhibiting pH-responsive release and efficient endosomal escape.

A novel intracellular protein delivery platform based on single-protein nanocapsules

2009 ◽  
Vol 5 (1) ◽  
pp. 48-53 ◽  
Author(s):  
Ming Yan ◽  
Juanjuan Du ◽  
Zhen Gu ◽  
Min Liang ◽  
Yufang Hu ◽  
...  
Keyword(s):  
Protein Delivery ◽  
Intracellular Protein ◽  
Single Protein ◽  
Delivery Platform ◽  
Intracellular Protein Delivery

Combinatorial synthesis of redox-responsive cationic polypeptoids for intracellular protein delivery application

2020 ◽  
Vol 63 (11) ◽  
pp. 1619-1625
Author(s):  
Zhicheng Le ◽  
Tong Xiao ◽  
Zhijia Liu ◽  
Xingliang Liu ◽  
Hong Liu ◽  
...  
Keyword(s):  
Protein Delivery ◽  
Combinatorial Synthesis ◽  
Intracellular Protein ◽  
Redox Responsive ◽  
Intracellular Protein Delivery
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