A highly sensitive and selective fluorescent probe for hypochlorite in pure water with aggregation induced emission characteristics

2017 ◽  
Vol 196 ◽  
pp. 427-438 ◽  
Author(s):  
Can Wang ◽  
Hongyu Ji ◽  
Mengshu Li ◽  
Likun Cai ◽  
Zhipeng Wang ◽  
...  
Keyword(s):  
Water Solubility ◽  
Pure Water ◽  
Response Speed ◽  
Aqueous Samples ◽  
Strong Emission ◽  
Aggregation Induced Emission ◽  
Highly Sensitive ◽  
Wide Range ◽  
Distinct Increase

As a reactive oxygen species (ROS), hypochlorite (OCl−) plays a crucial role in oxidative stress and signal transduction, controlling a wide range of physiological functions. In addition, the wide use of OCl− in the treatment of food and water might possibly threaten human health if the residual quantity was out of limits. Currently, sensitive methods employed to selectively monitor OCl− in aqueous samples in situ are still scarce and badly needed. Boron esters or acids are considered to be suitable functional groups for the detection of hydrogen peroxide due to their reliable reactivity. In this work, we try to develop a highly sensitive and selective OCl− probe (TPE2B) based on the mechanism of aggregation induced emission (AIE). Due to the distinct increase in water solubility of TPE2OH, which is generated from the reaction between TPE2B and OCl−, the strong emission of TPE2B is quenched dramatically. The response speed was as fast as 30 seconds with a detection limit as low as 28 nM. Additionally, test papers were also fabricated and exhibited a highly sensitive response to 0.1 mM OCl−.

scholarly journals Highly sensitive and multiplexed in situ protein profiling with cleavable fluorescent streptavidin

2019 ◽  
Author(s):  
Renjie Liao ◽  
Diego Mastroeni ◽  
Paul D. Coleman ◽  
Jia Guo
Keyword(s):  
Signal Amplification ◽  
Individual Cell ◽  
Protein Detection ◽  
Protein Profiling ◽  
Detection Sensitivity ◽  
Layer By Layer ◽  
Protein Targets ◽  
Highly Sensitive ◽  
Wide Range

AbstractThe ability to perform highly sensitive and multiplexed in situ protein analysis is crucial to advance our understanding of normal physiology and disease pathogenesis. To achieve this goal, here we develop an approach using cleavable biotin conjugated antibodies and cleavable fluorescent streptavidin (CFS). In this approach, protein targets are first recognized by the cleavable biotin labeled antibodies. Subsequently, CFS is applied to stain the protein targets. Though layer-by-layer signal amplification using cleavable biotin conjugated orthogonal antibodies and CSF, the protein detection sensitivity can be enhanced by at least 10 fold, compared with the existing methods. After imaging, the fluorophores and the biotins unbound to streptavidin are removed by chemical cleavage. The leftover streptavidin is blocked by biotin. Upon reiterative analysis cycles, a large number of different proteins with a wide range of expression levels can be unambiguously detected in individual cell in situ.

scholarly journals Highly Sensitive Formaldehyde Detection Using Well-Aligned Zinc Oxide Nanosheets Synthesized by Chemical Bath Deposition Technique

2018 ◽  
Author(s):  
Eun-Bi Kim ◽  
Hyung Kee Seo
Keyword(s):  
Chemical Sensor ◽  
In Situ Deposition ◽  
Highly Sensitive ◽  
Wide Range ◽  
Zno Nanosheets ◽  
Effect Transistor ◽  
Serious Injury ◽  
Synthesized Materials ◽  
Zinc Oxide Nanosheets

Detection of formaldehyde is very important in terms of life protection, as it can cause serious injury to eyes, skin, mouth and gastrointestinal function if indirectly inhaled and hence researchers are putting effort in developing novel and sensitive device. In this work, we have fabricated an electro-chemical sensor in the form of a field effect transistor (FET) to detect formaldehyde over wide range (10 nM to 1 mM). For this, ZnO nanosheets (NS) were first synthesized by hydrothermal method with in-situ deposition on cleaned SiO2 coated Si (100) substrate. The synthesized materials were characterized for morphology and purity and surface area (31.718 m2/g). The developed device was tested for formaldehyde detection at room temperature that resulted in a linear response with concentration (96%), sensitivity value of 0.27 mA/M/cm2 and a low detection limit of 210 nM, and a high 0.93194 return.

scholarly journals A Perspective on Recent Advances in Piezoelectric Chemical Sensors for Environmental Monitoring and Foodstuffs Analysis

Chemosensors ◽  
2019 ◽  
Vol 7 (3) ◽  
pp. 39 ◽  
Author(s):  
Kuchmenko ◽  
Lvova
Keyword(s):  
Chemical Sensors ◽  
Metal Ion ◽  
Sample Pretreatment ◽  
Cost Effective ◽  
Bulk Acoustic Wave ◽  
Multisensor Systems ◽  
Highly Sensitive ◽  
Wide Range ◽  
Wastewater Samples

This paper provides a selection of the last two decades publications on the development and application of chemical sensors based on piezoelectric quartz resonators for a wide range of analytical tasks. Most of the attention is devoted to an analysis of gas and liquid media and to industrial processes controls utilizing single quartz crystal microbalance (QCM) sensors, bulk acoustic wave (BAW) sensors, and their arrays in e-nose systems. The unique opportunity to estimate several heavy metals in natural and wastewater samples from the output of a QCM sensor array highly sensitive to changes in metal ion activity in water vapor is shown. The high potential of QCM multisensor systems for fast and cost-effective water contamination assessments “in situ” without sample pretreatment is demonstrated.

scholarly journals Highly Sensitive Formaldehyde Detection Using Well-Aligned Zinc Oxide Nanosheets Synthesized by Chemical Bath Deposition Technique

Materials ◽  
2019 ◽  
Vol 12 (2) ◽  
pp. 250 ◽  
Author(s):  
Eun-Bi Kim ◽  
Hyung-Kee Seo
Keyword(s):  
Chemical Sensor ◽  
Limit Of Detection ◽  
In Situ Deposition ◽  
Highly Sensitive ◽  
Wide Range ◽  
Zno Nanosheets ◽  
Concentration Sensitivity ◽  
Serious Injury ◽  
Synthesized Materials

Detection of formaldehyde is very important in terms of life protection, as it can cause serious injury to eyes, skin, mouth and gastrointestinal function if indirectly inhaled. Researchers are therefore putting effort into developing novel and sensitive devices. In this work, we have fabricated an electro-chemical sensor in the form of a field effect transistor (FET) to detect formaldehyde over a wide range (10 nM to 1 mM). For this, ZnO nanosheets (NS) were first synthesized by hydrothermal method with in-situ deposition on cleaned SiO2/Si (100) substrate. The synthesized materials were characterized for morphology and purity and surface area (31.718 m2/g). The developed device was tested for formaldehyde detection at room temperature that resulted in a linear (96%) and reproducible response with concentration, sensitivity value of 0.27 mA/M/cm2 with an error of ±2% and limit of detection (LOD) as 210 nM.

scholarly journals Sampling methane in basalt on Earth and Mars

2013 ◽  
Vol 12 (2) ◽  
pp. 113-122 ◽  
Author(s):  
Sean McMahon ◽  
John Parnell ◽  
Nigel J.F. Blamey
Keyword(s):  
Mass Spectrometry ◽  
Martian Surface ◽  
Low Concentrations ◽  
Geothermal Activity ◽  
Mass Spectrometry Technique ◽  
Highly Sensitive ◽  
Wide Range ◽  
Spectrometry Technique ◽  
Hydrothermal Mineral

AbstractIf confirmed, the extremely low concentrations of methane (CH4) detected in the Martian atmosphere may represent reservoirs and emission processes that would normally be considered negligible on Earth. One such process is the release of ancient volatiles from fluid inclusions and interstitial sites in rocks and minerals during erosion or geothermal activity. Using a highly sensitive rock-crushing and mass-spectrometry technique previously shown to detect CH4 in serpentinites and hydrothermal mineral deposits, we have demonstrated that CH4 and other ancient volatiles can be recovered from basalt, the dominant rock type on the Martian surface. Basalt samples from a wide range of ages and geological systems were tested, all of which released CH4 when crushed. Oxidative weathering was associated with lower quantities of CH4. Otherwise, CH4 recoverability showed no relationship with age or geological context. Mineral veins, cross-cutting one locality were found to share the volatile composition of the basalt. In general, the results suggest that CH4-release from ancient basalts could be a significant process on Mars, which could be further investigated by Martian rovers using a similar rock-crushing and mass spectrometry technique in situ.

scholarly journals Highly Sensitive Formaldehyde Detection Using Well-Aligned Zinc Oxide Nanosheets Synthesized by Chemical Bath Deposition Technique

2018 ◽  
Author(s):  
Eun-Bi Kim ◽  
Hyung-Kee Seo
Keyword(s):  
Chemical Sensor ◽  
In Situ Deposition ◽  
Highly Sensitive ◽  
Wide Range ◽  
Zno Nanosheets ◽  
Effect Transistor ◽  
Serious Injury ◽  
Synthesized Materials ◽  
Zinc Oxide Nanosheets

Detection of formaldehyde is very important in terms of life protection, as it can cause serious injury to eyes, skin, mouth and gastrointestinal function if indirectly inhaled and hence researchers are putting effort in developing novel and sensitive device. In this work, we have fabricated an electro-chemical sensor in the form of a field effect transistor (FET) to detect formaldehyde over wide range (10 nM to 1 mM). For this, ZnO nanosheets (NS) were first synthesized by hydrothermal method with in-situ deposition on cleaned SiO2 coated Si (100) substrate. The synthesized materials were characterized for morphology and purity and surface area (31.718 m2/g). The developed device was tested for formaldehyde detection at room temperature that resulted in a linear response with concentration (96%), sensitivity value of 0.27 mA/M/cm2 and a low detection limit of 210 nM, and a high 0.93194 return.

scholarly journals Towards <i>in-situ</i> U–Pb dating of dolomites

2020 ◽  
Author(s):  
Bar Elisha ◽  
Perach Nuriel ◽  
Andrew Kylander-Clark ◽  
Ram Weinberger
Keyword(s):  
High Resolution ◽  
Imaging Techniques ◽  
Dolomitic Rock ◽  
Icp Ms ◽  
Highly Sensitive ◽  
Wide Range ◽  
Absolute Dating ◽  
Crater Morphology ◽  
Epigenetic Processes

Abstract. Recent U–Pb dating by laser ablation ICP-MS has demonstrated that reasonable precision (3–10 % 2σ) can be achieved for high-resolution dating of texturally distinct calcite phases. Absolute dating of dolomite, for which biostratigraphy and traditional dating techniques are very limited, remains challenging but may resolve many fundamental questions related to the timing of mineral-rock formation by syngenetic, diagenesis, hydrothermal, and epigenetic processes. In this study we explore the possibility of dating dolomitic rocks via recent LA-ICP-MS dating techniques developed for calcite. The in-situ U–Pb dating was tested on a wide range of dolomite rocks of various origins (i.e., syngenetic, early diagenetic and epigenetic) from the Cambrian to Pliocene age – all of which from well-constrained stratigraphic sections in Israel. We present in-situ U–Pb results of dolomitic rock samples, together with imaging techniques and chemical characterizations. We show that dolomite dating is highly sensitive to textural differences and highlight parameters such as crater morphology and roughness, calcite zoning and impurities that may affect the interpretation of the resulted ages. Textural examination indicates zonation and mixing of different phases at the sub-millimeter scale (

scholarly journals Highly Sensitive and Multiplexed In-Situ Protein Profiling with Cleavable Fluorescent Streptavidin

Cells ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 852 ◽  
Author(s):  
Renjie Liao ◽  
Thai Pham ◽  
Diego Mastroeni ◽  
Paul D. Coleman ◽  
Joshua Labaer ◽  
...  
Keyword(s):  
Optical Resolution ◽  
Protein Detection ◽  
Protein Analysis ◽  
Protein Profiling ◽  
Detection Sensitivity ◽  
Layer By Layer ◽  
Protein Targets ◽  
Highly Sensitive ◽  
Wide Range

The ability to perform highly sensitive and multiplexed in-situ protein analysis is crucial to advance our understanding of normal physiology and disease pathogenesis. To achieve this goal, we here develop an approach using cleavable biotin-conjugated antibodies and cleavable fluorescent streptavidin (CFS). In this approach, protein targets are first recognized by the cleavable biotin-labeled antibodies. Subsequently, CFS is applied to stain the protein targets. Though layer-by-layer signal amplification using cleavable biotin-conjugated orthogonal antibodies and CSF, the protein detection sensitivity can be enhanced at least 10-fold, compared with the current in-situ proteomics methods. After imaging, the fluorophore and the biotin unbound to streptavidin are removed by chemical cleavage. The leftover streptavidin is blocked by biotin. Upon reiterative analysis cycles, a large number of different proteins with a wide range of expression levels can be profiled in individual cells at the optical resolution. Applying this approach, we have demonstrated that multiple proteins are unambiguously detected in the same set of cells, regardless of the protein analysis order. We have also shown that this method can be successfully applied to quantify proteins in formalin-fixed paraffin-embedded (FFPE) tissues.

A Highly Sensitive Fluorescent Sensor for Amitrole Determination in Aqueous Samples

NANO ◽  
2017 ◽  
Vol 12 (07) ◽  
pp. 1750071
Author(s):  
Yue Wang ◽  
Danqun Huo ◽  
Jingzhou Hou ◽  
Junjie Li ◽  
Mei Yang ◽  
...  
Keyword(s):  
Fluorescent Sensor ◽  
Low Cost ◽  
High Sensitivity ◽  
Inner Filter Effect ◽  
Aqueous Samples ◽  
Cdte Qds ◽  
Sensor Platform ◽  
Highly Sensitive ◽  
Wide Range ◽  
Optimized Conditions

A simple yet sensitive fluorescent sensor was reported for amitrole analysis based on integration of gold nanoparticles (AuNPs) and CdTe quantum dots (CdTe QDs) via inner filter effect (IFE). The fluorescence of GSH-coated CdTe QDs can be significantly quenched by AuNPs, and gradually restored in the presence of amitrole. Addition of amitrole induced AuNPs aggregation and decreased their characteristic surface plasmon absorption, which diminished the IFE between them. The sensor platform realized high sensitivity and good reproducibility in low concentration amitrole ranging from 9.5[Formula: see text]nM to 1000[Formula: see text]nM with a detection limit down to 4.75[Formula: see text]nM under the optimized conditions. It also resisted a wide range of interfering counterparts and showed analytical performance comparable to the majority of analytical methods reported in prior studies. We envisioned the first fluorescent amitrole sensor would be potentially useful for low cost on-site amitrole monitoring in real application.

Energetics of water in the Solar System

2021 ◽  
Author(s):  
Akshay Rao ◽  
Abhimanyu Das ◽  
Owen Li ◽  
David Warsinger
Keyword(s):  
Solar System ◽  
Pure Water ◽  
Resource Extraction ◽  
Water Harvesting ◽  
Highly Sensitive ◽  
Fuel Reformation ◽  
Vapor Mixtures ◽  
System 1 ◽  
Physical Mixtures

Abstract Water is vital for space exploration, from drinking to fuel reformation, and is naturally abundant in the Solar System [1–16]. While in-situ resource utilization (ISRU) requires vastly less energy than transporting resources, the energetics has scarcely been explored besides on Earth and limited analysis on Mars’ vapor. Here, we develop a thermodynamic framework to quantify the energy requirements for resource extraction from 18 water sources on 11 planetary bodies. We find that desalinating saline liquid brines, where available, could be the most energetically favorable option and the energy required to access water vapor can be four to ten times higher than accessing ice deposits. While desalination energetics are highly sensitive to salt concentration, we show that desalination energetics only vary by a factor of 2 with respect to the type of salt present. Additionally, unlike chemical mixtures, the minimum energetics are insensitive to composition in physical mixtures (e.g., ice-regolith and inert vapor mixtures). Additionally, by deriving and computing the equation-of-state for pure water, we extend the least work estimates of atmospheric water harvesting by 94°C lower than previous studies that depend on predetermined databases. The presented approach and data may inform decisions regarding water harvesting, habitation, and resource reformation.

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