scholarly journals Impact of in vitro gastrointestinal digestion on the chemical composition, bioactive properties, and cytotoxicity of Vitis vinifera L. cv. Syrah grape pomace extract

2019 ◽  
Vol 10 (4) ◽  
pp. 1856-1869 ◽  
Author(s):  
Joana R. Costa ◽  
Manuela Amorim ◽  
Ana Vilas-Boas ◽  
Renata V. Tonon ◽  
Lourdes M. C. Cabral ◽  
...  

Grape pomace (GP) is a major byproduct worldwide, and it is well known for its bioactive compounds, such as fibers and phenolic compounds, that are popular for their impact upon human health, including in gastrointestinal health.

2016 ◽  
Vol 20 ◽  
pp. 291-302 ◽  
Author(s):  
Daniele Fraternale ◽  
Alexander Rudov ◽  
Francesco Prattichizzo ◽  
Fabiola Olivieri ◽  
Donata Ricci ◽  
...  

2014 ◽  
Vol 13 (2) ◽  
pp. 162-171 ◽  
Author(s):  
Martin Sák ◽  
Ivana Dokupilová ◽  
Daniel Mihálik ◽  
Jana Lakatošová ◽  
Marcela Gubišová ◽  
...  

Abstract The in vitro cell cultures of Vitis vinifera L. cv. St. Laurent were treated with two elicitors - synthetic methyl jasmonate and natural, prepared from grapevine plant infected with the Phaeomoniella chlamydospora, the agent causing the Esca disease of grapevine. Efficiency of phenolic compounds production after elicitation of cell culture was analysed immediately after treatment (15 min, 30 min, 60 min) and later (after 24, 48, and 72 hours). The cell growth and content of phenolic compounds (+)-catechin, (-)-epicatechin, p-coumaric acid, syringaldehyde, rutin, vanillic acid, and trans-resveratrol were analysed in cultivated cells as well as in cultivation medium. Pch-treatment increased production of total polyphenols the most significantly 15 min after the elicitation and in optimal time was 2.86 times higher than in nonelicited culture and 1.44 times higher than in MeJa induced cell culture.


2015 ◽  
Vol 6 (8) ◽  
pp. 2453-2463 ◽  
Author(s):  
E. Sangiovanni ◽  
C. Di Lorenzo ◽  
E. Colombo ◽  
F. Colombo ◽  
M. Fumagalli ◽  
...  

Vitis viniferaL. water extract from dried leaves maintains its anti-inflammatory activity afterin vitrogastric digestion.


Pharmaceutics ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 1148
Author(s):  
Alexandra A. Hübner ◽  
Fernanda D. Sarruf ◽  
Camila A. Oliveira ◽  
Alberto V. Neto ◽  
Dominique C. H. Fischer ◽  
...  

In winemaking, a large amount of grape pomace is produced that is rich in polyphenolics and highly beneficial for human health, as phenols are useful for skin ultraviolet (UV) protection. In this investigation, we evaluated the safety and clinical efficacy of a sunscreen system containing a grape pomace extract from Vitis vinifera L. as a bioactive ingredient. The recovery of phenolics in the waste was performed by percolation. Nine emulsions were developed using a factorial design and two were evaluated clinically: Formulation E, containing only UV filters (butylmethoxydibenzoyl methane, ethylhexyl methoxycinnamate and ethylhexyl dimethyl PABA), and F, with the extract at 10.0% w/w + UV filters. The antioxidant activity was determined by the DPPH assay and the in vitro efficacy was established by sun protection factor (SPF) measurements (Labsphere UV-2000S). Clinical tests were performed to determine safety (human repeated insult patch test) and to confirm efficacy (photoprotective effectiveness in participants). The results showed a synergistic effect between the sunscreen system and the extract on UVB protection and antioxidant activity. Both samples were considered safe. Formulation F was 20.59% more efficient in protecting skin against UVB radiation, taking approximately 21% more time to induce erythema compared to the extract-free sample.


2014 ◽  
Vol 34 (1) ◽  
pp. 135-142 ◽  
Author(s):  
Eldina Castro Sousa ◽  
Ana Maria Athayde Uchôa-Thomaz ◽  
José Osvaldo Beserra Carioca ◽  
Selene Maia de Morais ◽  
Alessandro de Lima ◽  
...  

LWT ◽  
2021 ◽  
pp. 112066
Author(s):  
Karine Inês Bolson Moro ◽  
Ana Betine Beutinger Bender ◽  
Daniele de Freitas Ferreira ◽  
Caroline Sefrin Speroni ◽  
Juliano Smanioto Barin ◽  
...  

Plants ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 490
Author(s):  
Martin Sák ◽  
Ivana Dokupilová ◽  
Šarlota Kaňuková ◽  
Michaela Mrkvová ◽  
Daniel Mihálik ◽  
...  

The in vitro cell cultures derived from the grapevine (Vitis vinifera L.) have been used for the production of stilbenes treated with different biotic and abiotic elicitors. The red-grape cultivar Váh has been elicited by natural cellulose from Trichoderma viride, the cell wall homogenate from Fusarium oxysporum and synthetic jasmonates. The sodium-orthovanadate, known as an inhibitor of hypersensitive necrotic response in treated plant cells able to enhance production and release of secondary metabolite into the cultivation medium, was used as an abiotic elicitor. Growth of cells and the content of phenolic compounds trans-resveratrol, trans-piceid, δ-viniferin, and ɛ-viniferin, were analyzed in grapevine cells treated by individual elicitors. The highest accumulation of analyzed individual stilbenes, except of trans-piceid has been observed after treatment with the cell wall homogenate from F. oxysporum. Maximum production of trans-resveratrol, δ- and ɛ-viniferins was triggered by treatment with cellulase from T. viride. The accumulation of trans-piceid in cell cultures elicited by this cellulase revealed exactly the opposite effect, with almost three times higher production of trans-resveratrol than that of trans-piceid. This study suggested that both used fungal elicitors can enhance production more effectively than commonly used jasmonates.


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