Zn capped Al2O3 and TiO2 nanoporous arrays as pH sensitive drug delivery systems: a combined experimental and simulation study

2020 ◽  
Vol 44 (38) ◽  
pp. 16602-16612
Author(s):  
Rokhsareh Khodabandeh ◽  
Fatemeh Mohammadpour ◽  
Amin Reza Zolghadr ◽  
Axel Klein

pH sensitive nanotube arrays based on Zn capped Al2O3 and TiO2 were reported for the release of vitamin C in an experimental/theoretical study using MD simulations.

2020 ◽  
Vol 44 (41) ◽  
pp. 18102-18102
Author(s):  
Rokhsareh Khodabandeh ◽  
Fatemeh Mohammadpour ◽  
Amin Reza Zolghadr ◽  
Axel Klein

Correction for ‘Zn capped Al2O3 and TiO2 nanoporous arrays as pH sensitive drug delivery systems: a combined experimental and simulation study’ by Rokhsareh Khodabandeh et al., New J. Chem., 2020, 44, 16602–16612, DOI: 10.1039/D0NJ02840A.


2021 ◽  
Vol 22 ◽  
Author(s):  
Vaidevi Sethuraman ◽  
Kumar Janakiraman ◽  
Venkateshwaran Krishnaswami ◽  
Ruckmani Kandasamy

Abstract: Stimuli responsive nanocarriers are gaining much attention due to its versatile multifunctional activities including disease diagnosis and treatment. Recently, clinical applications of nano drug delivery systems for cancer treatment make a considerable challenge due to its limited cellular uptake, low bioavailability, poor targetability, stability issues, and unfavourable pharmacokinetics. To overcome these issues researchers are focussing on stimuli responsive systems. Nano carriers elicit its role through endogenous (pH, temperature, enzyme and redox) or exogenous (temperature, light, magnetic field, ultrasound) stimulus. These systems were designed to overcome the shortcomings such as non-specificity and toxicity associated with the conventional drug delivery systems. The pH variation between healthy cells and tumor microenvironment creates a platform towards the generation of pH sensitive nano delivery systems. Herein, we propose to present an overview of various internal and external stimuli responsive behavior based drug delivery systems. Herein the present review will focus specifically on the significance of various pH- responsive nanomaterials such as polymeric nanoparticles, nano micelles, inorganic based pH sensitive drug delivery carriers such as calcium phosphate nanoparticles, and carbon dots in cancer treatment. Moreover, this review elaborates the recent findings on pH based stimuli responsive drug delivery system with special emphasis towards our reported stimuli responsive systems for cancer treatment.


2012 ◽  
Vol 125 (4) ◽  
pp. 3006-3013 ◽  
Author(s):  
I. Altimari ◽  
U. G. Spizzirri ◽  
F. Iemma ◽  
M. Curcio ◽  
F. Puoci ◽  
...  

2009 ◽  
Vol 68 (2) ◽  
pp. 245-249 ◽  
Author(s):  
Cui-Yun Yu ◽  
Bo-Cheng Yin ◽  
Wei Zhang ◽  
Si-Xue Cheng ◽  
Xian-Zheng Zhang ◽  
...  

2016 ◽  
Vol 196 ◽  
pp. 81-88 ◽  
Author(s):  
Tianjing Zhao ◽  
Devid Maniglio ◽  
Jie Chen ◽  
Bin Chen ◽  
Claudio Migliaresi

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