One pot, microwave-assisted copper(I)-catalyzed dithiocarbamation: A facile introduction of dithiocarbamate on imidazopyridines

2021 ◽  
Author(s):  
Kritika Laxmikeshav ◽  
Akash P Sakla ◽  
Stephy Elza John ◽  
Shankaraiah Nagula
Keyword(s):  
Molecular Oxygen ◽  
Water Soluble ◽  
One Pot ◽  
Microwave Assisted

A facile and proficient dithiocarbamation of imidazo[1,2-a]pyridines and other imidazoheterocycles with in situ generated dithiocarbamates is established using a water-soluble, stable copper(I) catalyst and molecular oxygen under microwave conditions. The...

scholarly journals One-Pot Microwave-Assisted Synthesis of Water-Soluble Pyran-2,4,5-triol Glucose Amine Schiff Base Derivative: XRD/HSA Interactions, Crystal Structure, Spectral, Thermal and a DFT/TD-DFT

Crystals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 117
Author(s):  
Yousef Hijji ◽  
Rajeesha Rajan ◽  
Hamdi Ben Yahia ◽  
Said Mansour ◽  
Abdelkader Zarrouk ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Orbital ◽  
Density Functional ◽  
Condensation Reaction ◽  
3D Structure ◽  
Water Soluble ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Microwave Assisted ◽  
Td Dft

The(3R,4R,6R)-3-(((E)-2-hydroxybenzylidene)amino)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol water-soluble Glucose amine Schiff base (GASB-1) product was made available by condensation of 2-hydroxybenzaldehyde with (3R,6R)-3-amino-6-(hydroxymethyl)-tetra-hydro-2H-pyran-2,4,5-triol under mono-mode microwave heating. A one-pot 5-minute microwave-assisted reaction was required to complete the condensation reaction with 90% yield and without having byproducts. The 3D structure of GASB-1 was solved from single crystal X-ray diffraction data and computed by DFT/6-311G(d,p). The Hirshfeld surface analysis (HSA), molecular electronic potential (MEP), Mulliken atomic charge (MAC), and natural population analysis (NPA) were performed. The IR and UV-Vis spectra were matched to their density functional theory (DFT) relatives and the thermal behavior was resolved in an open-room condition via thermogravimetry/Derivative thermogravimetry (TG/DTG) and differential scanning calorimetry (DSC). The highest occupied molecular orbital/lowest unoccupied molecular orbital (HOMO/LUMO), density of state (DOS), and time-dependence TD-DFT computations were correlated to the experimental electron transfer in water and acrylonitrile solvents.

scholarly journals Ligand-Free (Z)-Selective Transfer Semihydrogenation of Alkynes Catalyzed by in situ Generated Oxidizable Copper Nanoparticles

2021 ◽  
Author(s):  
Rafał Kusy ◽  
Karol Grela
Keyword(s):  
Suzuki Reaction ◽  
Ammonia Borane ◽  
Water Soluble ◽  
Selective Transfer ◽  
One Pot ◽  
Ammonia Complex ◽  
Ligand Free ◽  
Simple Phase ◽  
Operational Simplicity

Herein, we present (<i>Z</i>)-selective transfer semihydrogenation of alkynes based on in situ generated CuNPs in the presence of hydrogen donors, such as ammonia-borane and a protic solvent. This environmentally-friendly method is characterized by operational simplicity combined with high stereo- and chemoselectivity and functional group compatibility. Auto-oxidation of CuNPs after the semihydrogenation reaction is completed results in the formation of water-soluble ammonia complex, so that the catalyst may be reused several times by simple phase-separation with no need of any special regeneration process. Formed NH<sub>4</sub>B(OR)<sub>4</sub> can be easily transformed back to ammonia-borane or to boric acid. In addition, one-pot tandem sequence involving Suzuki reaction followed by semihydrogenation was presented.<br>

scholarly journals Microwave assisted one-pot green synthesis of cinnoline derivatives inside natural sporopollenin microcapsules

RSC Advances ◽  
2018 ◽  
Vol 8 (41) ◽  
pp. 23241-23251 ◽  
Author(s):  
Amro K. F. Dyab ◽  
Kamal Usef Sadek
Keyword(s):  
Green Synthesis ◽  
One Pot ◽  
Microwave Assisted

We have achievedin situmicrowave assisted green syntheses of a novel cinnoline derivative inside natural sporopollenin microreactors.

scholarly journals Microwave-assisted one-pot synthesis of water-soluble rare-earth doped fluoride luminescent nanoparticles with tunable colors

2012 ◽  
Vol 525 ◽  
pp. 154-158 ◽  
Author(s):  
Cong-Cong Mi ◽  
Zhen-huang Tian ◽  
Bao-fu Han ◽  
Chuan-bin Mao ◽  
Shu-kun Xu
Keyword(s):  
Rare Earth ◽  
Water Soluble ◽  
One Pot ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
Luminescent Nanoparticles ◽  
Rare Earth Doped

scholarly journals Asymmetric one-pot synthesis of cyclopropanes

2016 ◽  
Vol 35 (1) ◽  
pp. 45
Author(s):  
Naoufel Ben Hamadi ◽  
Ahlem Guesmi ◽  
Wided Nouira
Keyword(s):  
Escherichia Coli ◽  
Water Soluble ◽  
Gram Negative Bacteria ◽  
Protecting Group ◽  
Gram Positive ◽  
One Pot ◽  
Gram Negative ◽  
Activity Screening ◽  
High Yields

Cycloaddition of the diazoalkanes to electron-deficient olefins (in situ) affords polysubstituted cyclopropanes in high yields (up to 85%). Deprotection of the ketal protecting group provided water-soluble cyclopropane-bearing carbohydrate in good yields. Antimicrobial activity screening of the synthesized compounds 8 and 9, utilizing a variety of Gram-positive (Staphylococcus aureus and Enterococcus fecalis), Gram-negative bacteria (Escherichia coli and Klebsiella pneumoniae) and yeast (Candida albicans), exhibited that all the prepared analogues acquire promising activities against both Gram-positive and Gram-negative bacteria especially compounds 9b and 9c (antimicrobial active agents against Gram-negative bacteria).

scholarly journals A Novel One-Pot and One-Step Microwave-Assisted Cyclization-Methylation Reaction of Amino Alcohols and Acetylated Derivatives with Dimethyl Carbonate and TBAC

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Adrián Ochoa-Terán ◽  
Leticia Guerrero ◽  
Ignacio A. Rivero
Keyword(s):  
Ionic Liquid ◽  
Dimethyl Carbonate ◽  
Amino Alcohols ◽  
Diethyl Carbonate ◽  
One Pot ◽  
Microwave Assisted ◽  
Methylation Reaction ◽  
One Step ◽  
Better Than

A simple and efficient microwave-assisted methodology for the synthesis of 4-substituted-3-methyl-1,3-oxazolidin-2-ones from amino alcohols catalyzed by a ionic liquid was developed. This novel one-pot and one-step cyclization-methylation reaction represents an easier and faster method than any other reported protocols that can be used to obtain the desired products in good yields and high purity. Applying microwave irradiation at 130°C in the presence of TBAC, dimethyl carbonate acts simultaneously as carbonylating and methylating agent and surprisingly promotes anin situbasic trans esterification when aN-acetylated amino alcohol is used as starting material. Furthermore, dimethyl carbonate worked better than diethyl carbonate in performing this reaction.

scholarly journals Novel phthiocol-based organometallics with tridentate coordination motif and their unexpected cytotoxic behaviour

2020 ◽  
Vol 49 (5) ◽  
pp. 1393-1397 ◽  
Author(s):  
Heiko Geisler ◽  
Debora Wernitznig ◽  
Michaela Hejl ◽  
Natalie Gajic ◽  
Michael A. Jakupec ◽  
...  
Keyword(s):  
One Pot ◽  
Microwave Assisted

Novel phthiocol-based organometallics with in situ formed tridentate N,O,O-coordination motif were established via three-component microwave assisted one-pot reaction.

LiTi2(PO4)3/reduced graphene oxide nanocomposite with enhanced electrochemical performance for lithium-ion batteries

RSC Advances ◽  
2014 ◽  
Vol 4 (60) ◽  
pp. 31672-31677 ◽  
Author(s):  
Ha-Kyung Roh ◽  
Hyun-Kyung Kim ◽  
Kwang Chul Roh ◽  
Kwang-Bum Kim
Keyword(s):  
Heat Treatment ◽  
Graphene Oxide ◽  
Rate Capability ◽  
Lithium Ion ◽  
Cycling Performance ◽  
One Pot ◽  
Microwave Assisted ◽  
Reduced Graphene ◽  
Enhanced Electrochemical Performance

NASICON-structured LiTi2(PO4)3/rGO nanocomposite was successfully fabricated by in situ synthesis of a Li–Ti–P–O/rGO precursor by microwave-assisted one-pot method followed by calcination heat treatment. Electrodes prepared from the nanocomposites provide excellent cycling performance and rate capability, indicating great potential for their use in LIBs.

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