Synthesis of Disubstituted γ-Butyrolactones and Spirocyclopropanes via Multicomponent Reaction of Aldehydes, Meldrum’s Acid and Sulfoxonium Ylides

2021 ◽  
Author(s):  
Shan-Shan Li ◽  
Qi Qin ◽  
Zhuang Qi ◽  
Li-Miao Yang ◽  
Yun Kang ◽  
...  
Keyword(s):  
Multicomponent Reaction ◽  
Aromatic Aldehydes ◽  
Efficient Synthesis ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
Mild Conditions

An efficient synthesis of disubstituted γ-butyrolactones and spirocyclopropanes via multicomponent reaction of aldehydes, Meldrum’s acid and sulfoxonium ylides has been developed. Under mild conditions, electron-rich aromatic aldehydes reacted with Meldrum’s...

A Novel Route for the Diastereoselective Synthesis of Dispiro[tetrahydroquinoline-bis(2,2-dimethyl[1,3]dioxane-4,6-dione)] Derivatives via a One-Pot Domino Multicomponent Reaction of Arylamines, Aromatic Aldehydes, and Meldrum's Acid

2014 ◽  
Vol 52 (3) ◽  
pp. 873-879 ◽  
Author(s):  
Mojtaba Lashkari ◽  
Malek Taher Maghsoodlou ◽  
Nourallah Hazeri ◽  
Sayyed Mostafa Habibi-Khorassani ◽  
Niloufar Akbarzadeh Torbati ◽  
...  
Keyword(s):  
Multicomponent Reaction ◽  
Aromatic Aldehydes ◽  
Diastereoselective Synthesis ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot

Ir(iii)-Catalyzed [4 + 2] cyclization of azobenzene and diazotized Meldrum's acid for the synthesis of cinnolin-3(2H)-one

2019 ◽  
Vol 17 (9) ◽  
pp. 2554-2563 ◽  
Author(s):  
Gongutri Borah ◽  
Pitambar Patel
Keyword(s):  
Carboxylic Acid ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
First Report ◽  
Mild Conditions ◽  
Ester Derivative

The first report on Ir(iii)-catalyzed C–H alkylation/cyclization of azobenzene with diazotized Meldrum's acid was developed for the synthesis of cinnoline-3(2H)-one-4-carboxylic acid and its ester derivative under mild conditions.

Synthesis of coumarin-3-carboxylic esters via FeCl3-catalyzed multicomponent reaction of salicylaldehydes, Meldrum's acid and alcohols

Tetrahedron ◽  
2015 ◽  
Vol 71 (5) ◽  
pp. 863-868 ◽  
Author(s):  
Xinwei He ◽  
Yongjia Shang ◽  
Yao Zhou ◽  
Zhiyu Yu ◽  
Guang Han ◽  
...  
Keyword(s):  
Multicomponent Reaction ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
Carboxylic Esters

Efficient Synthesis of 5-Trifluoromethylthio-1,2,3-Triazoles: One-Pot Multicomponent Reaction from Elemental Sulfur and TMSCF3

Synthesis ◽  
2019 ◽  
Vol 52 (02) ◽  
pp. 304-310 ◽  
Author(s):  
Lin-Lin Zhang ◽  
Meng-Tian Li ◽  
Liang-Liang Shen ◽  
Qin-Pei Wu
Keyword(s):  
Multicomponent Reaction ◽  
Elemental Sulfur ◽  
Efficient Synthesis ◽  
One Pot ◽  
Mild Conditions ◽  
Multistep Reaction ◽  
Easy Operation

A sequential multistep reaction toward 5-trifluoromethyl­thio-1,2,3-triazoles has been established, starting from alkynes, organo­azides, S8, and (trifluoromethyl)trimethylsilane (TMSCF3). This reaction features mild conditions, easy operation, and readily available substrates.

Multicomponent and Regioselective Synthesis of Dihydropyrazolo[1,5-a]pyrimidines from Aromatic Aldehydes, Meldrum’s Acid, and Aminopyrazole CAN508

Heterocycles ◽  
2014 ◽  
Vol 89 (8) ◽  
pp. 1892 ◽  
Author(s):  
Petr Cankař ◽  
Lukáš Jedinák ◽  
Vladimír Kryštof ◽  
Zdeněk Trávníček
Keyword(s):  
Aromatic Aldehydes ◽  
Regioselective Synthesis ◽  
Meldrum's Acid ◽  
Meldrum’S Acid

One-Pot Three-Component Reaction between 2-Aminopyridines, Aldehydes and Meldrum’s Acid in Water: An Efficient Synthesis of β-Amino Acids

Synlett ◽  
2008 ◽  
Vol 2008 (20) ◽  
pp. 3177-3179 ◽  
Author(s):  
Mehdi Adib ◽  
Solmaz Fatemi ◽  
Meisam Nosrati ◽  
Hamid Bijanzadeh
Keyword(s):  
Amino Acids ◽  
Efficient Synthesis ◽  
Meldrum's Acid ◽  
Meldrum’S Acid ◽  
One Pot ◽  
Three Component Reaction
Sign in / Sign up

Export Citation Format

Share Document