Isolation of an actin-binding fragment of fibronectin
Keyword(s):
We have identified a specific actin-binding site in the adhesive glycoprotein fibronectin, isolated from chicken fibroblasts. Affinity chromatography of fragments, released from fibronectin by limited proteolysis with trypsin, chymotrypsin and subtilisin, on actin-Sepharose and other protein-Sepharose columns was used to locate the binding site. A 27 000-mol.wt. subtilisin-digest fragment bound efficiently to actin. The results suggest that the actin-binding site is close to, but not identical with, the reported collagen-binding site.
1991 ◽
Vol 266
(20)
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pp. 12989-12993
1992 ◽
Vol 267
(20)
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pp. 13993-13997
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1992 ◽
Vol 267
(11)
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pp. 7240-7244
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1991 ◽
Vol 266
(16)
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pp. 10485-10489
1998 ◽
Vol 273
(6)
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pp. 3661-3668
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2018 ◽
Vol 505
(3)
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pp. 879-884
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1992 ◽
Vol 11
(13)
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pp. 4739-4746
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