Failure to detect human herpesvirus type 8-DNA sequences in systemic plasmacytosis from HIV-uninfected Japanese patients

1999 ◽  
Vol 141 (2) ◽  
pp. 360-361 ◽  
Author(s):  
Watanabe ◽  
Tada ◽  
Nakamura ◽  
Tsuchida ◽  
Tamaki
Keyword(s):  
Dna Sequences ◽  
Human Herpesvirus ◽  
Japanese Patients ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type

scholarly journals Human Herpesvirus Type 8 DNA Sequences in Cell-Free Plasma and Mononuclear Cells of Kaposi's Sarcoma Patients

1996 ◽  
Vol 174 (5) ◽  
pp. 1101-1104 ◽  
Author(s):  
W. J. Harrington ◽  
O. Bagasra ◽  
C. E. Sosa ◽  
L. E. Bobroski ◽  
M. Baum ◽  
...  
Keyword(s):  
Dna Sequences ◽  
Kaposi's Sarcoma ◽  
Mononuclear Cells ◽  
Human Herpesvirus ◽  
Kaposi’S Sarcoma ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type ◽  
Free Plasma

Human herpesvirus type 8 DNA sequences in biological samples of HIV-positive and negative individuals in Sicily

AIDS ◽  
1997 ◽  
Vol 11 (5) ◽  
pp. 607-612 ◽  
Author(s):  
Enza Viviano ◽  
Francesco Vitale ◽  
Francesca Ajello ◽  
Anna Maria Perna ◽  
Maria Rosaria Villafrate ◽  
...  
Keyword(s):  
Dna Sequences ◽  
Biological Samples ◽  
Human Herpesvirus ◽  
Hiv Positive ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type

scholarly journals Serological and virological evidence of non-sexual transmission of human herpesvirus type 8 (HHV8)

2000 ◽  
Vol 125 (3) ◽  
pp. 671-675 ◽  
Author(s):  
F. VITALE ◽  
E. VIVIANO ◽  
A. M. PERNA ◽  
F. BONURA ◽  
G. MAZZOLA ◽  
...  
Keyword(s):  
General Population ◽  
Dna Sequences ◽  
Mononuclear Cells ◽  
Sexual Transmission ◽  
Human Herpesvirus ◽  
Seroprevalence Rate ◽  
Nested Polymerase Chain Reaction ◽  
Peripheral Blood Mononuclear ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type

To evaluate whether or not human herpesvirus 8 (HHV8) can be transmitted through a non-sexual route a serological survey was carried out in a group of 51 catholic nuns. The seroprevalence rate and the geometrical mean antibody titre to anti-latent HHV8 antigen were similar in nuns and in a group of 60 women, matched by age, in the general population (27 vs. 24%; 1028 vs. 1575, respectively). Moreover, by using nested polymerase chain reaction (PCR), HHV8 DNA sequences were detected in 7 of 16 (43·8%) saliva and peripheral blood mononuclear cells (PBMC) from patients with classical Kaposi's sarcoma (KS) and in 3 out of 7 (42%) AIDS-KS patients. None of 5 HIV positive persons who did not have KS tested positive for HHV8 DNA. HHV8 DNA sequences were also detected in 2 of 12 (17%) saliva and 1 PBMC sample out of 12 healthy HHV8 positive individuals (age range: 30–80 years old). This paper suggests that non-sexual transmission of HHV8 is operating in our geographical setting and saliva may be a potential source of HHV8 spreading in the general population.

Increased prevalence of human herpesvirus type 8 (HHV-8) genome among blood donors from North-Western Argentina

2016 ◽  
Vol 89 (3) ◽  
pp. 518-527 ◽  
Author(s):  
María Laura Hulaniuk ◽  
Oscar Torres ◽  
Sonia Bartoli ◽  
Lisandro Fortuny ◽  
Leandro Burgos Pratx ◽  
...  
Keyword(s):  
Blood Donors ◽  
Human Herpesvirus ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type ◽  
North Western

scholarly journals Immunohistochemical detection of the latent nuclear antigen-1 of the human herpesvirus type 8 to differentiate cutaneous epidemic Kaposi sarcoma and its histological simulators

2013 ◽  
Vol 88 (2) ◽  
pp. 243-246 ◽  
Author(s):  
Patricia Fonseca Pereira ◽  
Tullia Cuzzi ◽  
Maria Clara Gutierrez Galhardo
Keyword(s):  
Kaposi's Sarcoma ◽  
Human Herpesvirus ◽  
Kaposi Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Nuclear Antigen ◽  
Immunohistochemical Detection ◽  
Herpesvirus Type ◽  
Human Herpesvirus Type ◽  
Skin Biopsies ◽  
Latent Nuclear Antigen

Kaposi's sarcoma is the most common neoplasia diagnosed in AIDS patients and the expression of the human herpesvirus-8 (HHV-8) latent nuclear antigen-1 has been useful for its histological diagnosis. The aim of this study is to confirm that immunohistochemistry is a valuable tool for differentiating KS from its simulators in skin biopsies of HIV patients. Immunohistochemical and histological analyses were performed in 49 Kaposi's sarcoma skin biopsies and 60 of its histological simulators. Positivity was present in the 49 Kaposi's sarcoma skin biopsies and no staining was observed in the 60 simulators analyzed, resulting in sensibility and specificity of 100%. HHV-8 immunohistochemical detection is an effective tool for diagnosing Kaposi's sarcoma, especially in early lesions in which neoplastic features are not evident. It also contributes to its histological differential diagnosis.

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